Mouse Anti-FBXO38 Polyclonal Antibody – Cat# MBS643940

Western Blot analysis of FBXO38 expression in transfected 293T cell line by FBXO38 polyclonal antibody. Lane 1: FBXO38 transfected lysate (46.86kD). Lane 2: Non-transfected lysate.

FBXO38 Antibody – Mouse Polyclonal

Name: FBXO38 Antibody; Polyclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS643940
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643940

Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. May coactivate KLF7, but does not seem to promote KLF7 ubiquitination. More details

$880 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FBXO38, Polyclonal Antibody

Full Product Name

FBXO38 (F-box Only Protein 38, Modulator of KLF7 Activity Homolog, MoKA, SP329)

Product Gene Name

anti-FBXO38 antibody

Product Synonym Names

Anti -FBXO38 (F-box Only Protein 38, Modulator of KLF7 Activity Homolog, MoKA, SP329)

Immunogen Sequence

MEEGDAESSV CPRCCCHRPQ ESQRRTSRCS DEERPSTSRA CVVNGPDGTR SAFSFRTLPQ GGSSGPAHDE RTNGSGSGAT GEDRRGSSQP ESCDVQSNED YPRRPLTRAR SRLSHVLLVS ESEVAKTKPR HAMKRKRTAD KSTSTSDPVI EDDHVQVLVL KSKNLVGVTM TNCGITDLVL KDCPKMMFIH ATRCRVLKHL KVENAPIVNR FDYAQCKKLN MDQVLDQILR MPPERNRIIY LRPMQQVDTL TLEQKLFSGP YPYHICIIHE FSNPPNVRNK VRIRSWMDTI ANINQELIKY EFFPEATRSE EDLKKYPKYP WGREIYTLEG VVDGAPYSMI SDFPWLRSLR AAEPNSFARY DFEDDEESTI YAPRRKGQLS ADICMETIGE EISEMRQMKK GVFQRVVAIF IHYCDVNGEP VEDDYI

Clonality

Polyclonal

Isotype

IgG

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human FBXO38.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

133,944 Da

Chromosome Location

Chromosome: 5; NC_000005.9 (147763498..147822399). Location: 5q32

OMIM

608533

3D Structure

ModBase 3D Structure for Q6PIJ6

Immunogen

Full length human FBXO38, aa1-426 (AAH56147.1).

Product Categories/Family for anti-FBXO38 antibody

Antibodies; Abs to Ubiquitin Ligases

Applications Tested/Suitable for anti-FBXO38 antibody

Western Blot (WB)

Application Notes for anti-FBXO38 antibody

Suitable for use in Western Blot.

Other Notes

Small volumes of anti-FBXO38 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FBXO38 purchase

MBS643940 is an antibody targeting FBXO38. Also known as FBXO38 (F-box Only Protein 38, Modulator of KLF7 Activity Homolog, MoKA, SP329). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for FBXO38. It may not necessarily be applicable to this product.

NCBI GI #

50603739

NCBI GeneID

81545

NCBI Accession #

AAH78159.1

UniProt Primary Accession #

Q6PIJ6

UniProt Secondary Accession #

Q6PK72; Q7Z2U0; Q86VN3; Q9BXY6; Q9H837; Q9HC40

UniProt Related Accession #

Q6PIJ6

NCBI Official Full Name

FBXO38 protein, partial

NCBI Official Synonym Full Names

F-box protein 38

NCBI Official Symbol

FBXO38

NCBI Official Synonym Symbols

MOKA; Fbx38; SP329

UniProt Protein Name

F-box only protein 38

UniProt Synonym Protein Names

Modulator of KLF7 activity homolog

Protein Family

F-box only protein

UniProt Gene Name

FBXO38

UniProt Synonym Gene Names

MoKA

UniProt Entry Name

FBX38_HUMAN

NCBI Protein Information

F-box only protein 38; modulator of KLF7 activity homolog

NCBI Summary for FBXO38

This gene encodes a large protein that contains an F-box domain and may participate in protein ubiquitination. The encoded protein is a transcriptional co-activator of Krueppel-like factor 7 (Klf7). A heterozygous mutation in this gene was found in individuals with autosomal dominant distal hereditary motor neuronopathy type IID. There is a pseudogene for this gene on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

UniProt Comments for FBXO38

FBX38: Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. May coactivate KLF7, but does not seem to promote KLF7 ubiquitination. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 5q32

Cellular Component: cytoplasm; nucleus

Disease: Neuronopathy, Distal Hereditary Motor, Type Iid

Research Articles on FBXO38

1. This publication identifies the F-box protein 38 mouse ortholog and characterizes its interaction with KLF7 during regulation of cell cycle progression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-FBXO38 antibody

Organ/Tissue Name	Pubmed Publications
Mouth Antibodies	>1 publications with FBXO38 and Mouth