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ALDOC Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643955

ALDOC is a member of the fructose-biphosphate aldolase protein family. Expressed specifically in the hippocampus and Purkinje cells of the brain, this protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and… More details

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Product Overview

Online Datasheet in PDF
Product Name
ALDOC, Polyclonal Antibody
Full Product Name
ALDOC, CT (Fructose-bisphosphate Aldolase C, Brain-type Aldolase, ALDO, ALDC)
Product Gene Name
anti-ALDOC antibody
Product Synonym Names
Anti -ALDOC, CT (Fructose-bisphosphate Aldolase C, Brain-type Aldolase, ALDO, ALDC)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human ALDOC. Species sequence homology: Mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
39,456 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (26900133..26904282, complement). Location: 17cen-q12
OMIM
103870
3D Structure
ModBase 3D Structure for P09972
Immunogen
Synthetic peptide corresponding to human ALDOC at C-terminal (KLH).

Product Categories/Family for anti-ALDOC antibody

Antibodies; Abs to Enzymes
Applications Tested/Suitable for anti-ALDOC antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ALDOC antibody
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: ELISA: 1:1000
Western Blot: 1:50-1:100
Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml

Immunohistochemistry (IHC) of anti-ALDOC antibody

Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with ALDOC antibody followed by biotinylated goat rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.
Rabbit Anti-ALDOC Polyclonal Antibody – Cat# MBS643955

Western Blot (WB) of anti-ALDOC antibody

Western blot analysis of CEM cell line lysates (35ug/lane).
Rabbit Anti-ALDOC Polyclonal Antibody, Western Blot (WB) – Cat# MBS643955

Other Notes

Small volumes of anti-ALDOC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ALDOC purchase

MBS643955 is an antibody targeting ALDOC. Also known as ALDOC, CT (Fructose-bisphosphate Aldolase C, Brain-type Aldolase, ALDO, ALDC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ALDOC. It may not necessarily be applicable to this product.

NCBI GI #
49456717
NCBI GeneID
230
NCBI Accession #
CAG46679.1
UniProt Primary Accession #
P09972
UniProt Secondary Accession #
Q3SYL3; Q6FH94; Q6P0L5; B2R5R3
UniProt Related Accession #
P09972
NCBI Official Full Name
ALDOC
NCBI Official Synonym Full Names
aldolase C, fructose-bisphosphate
NCBI Official Symbol
ALDOC
NCBI Official Synonym Symbols
ALDC
UniProt Protein Name
Fructose-bisphosphate aldolase C
UniProt Synonym Protein Names
Brain-type aldolase
Protein Family
Fructose-bisphosphate aldolase
UniProt Gene Name
ALDOC
UniProt Synonym Gene Names
ALDC
UniProt Entry Name
ALDOC_HUMAN
NCBI Protein Information
fructose-bisphosphate aldolase C; aldolase 3; fructoaldolase C; brain-type aldolase; fructose-1,6-biphosphate triosephosphate lyase

NCBI Summary for ALDOC

This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]
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UniProt Comments for ALDOC

ALDOC: a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]

Protein type: Lyase; Carbohydrate Metabolism - fructose and mannose; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pentose phosphate pathway; EC 4.1.2.13

Chromosomal Location of Human Ortholog: 17cen-q12

Cellular Component: cytoskeleton; mitochondrion; axon; cytosol

Molecular Function: protein binding; cytoskeletal protein binding; fructose-bisphosphate aldolase activity

Biological Process: organ regeneration; glycolysis; apoptosis; glucose metabolic process; pathogenesis; response to organic nitrogen; response to organic cyclic substance; gluconeogenesis; protein homotetramerization; fructose 1,6-bisphosphate metabolic process; epithelial cell differentiation; carbohydrate metabolic process; response to hypoxia; protein heterotetramerization; aging; fructose metabolic process
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Research Articles on ALDOC

1. This protein has been found differentially expressed in the anterior cingulate cortex in men patients with schizophrenia.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ALDOC antibody

 Reference Product  PubMed Publications
 GAPDH antibody  >3 publications with ALDOC and GAPDH
 TPI1 antibody  >2 publications with ALDOC and TPI1
 FBP1 antibody  >1 publications with ALDOC and FBP1
 PFKM antibody  >1 publications with ALDOC and PFKM

Pathways associated with anti-ALDOC antibody

 Products by Pathway  Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Conversion Of Glucose To Acetyl CoA And Entry Into The TCA Cycle Pathway antibodies  Conversion Of Glucose To Acetyl CoA And Entry Into The TCA Cycle Pathway Diagram
 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
 Gluconeogenesis Pathway antibodies  Gluconeogenesis Pathway Diagram
 Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway antibodies  Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway Diagram
 Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway antibodies  Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway Diagram

Diseases associated with anti-ALDOC antibody

 Disease Name  Pubmed Publications
 Weight Loss Antibodies  >2 publications with ALDOC and Weight Loss
 Abnormalities, Drug-Induced Antibodies  >1 publications with ALDOC and Abnormalities, Drug-Induced
 Neoplasms Antibodies  >1 publications with ALDOC and Neoplasms
 Nerve Degeneration Antibodies  >1 publications with ALDOC and Nerve Degeneration
 Nervous System Diseases Antibodies  >1 publications with ALDOC and Nervous System Diseases
 Inflammation Antibodies  >1 publications with ALDOC and Inflammation

Organs/Tissues associated with anti-ALDOC antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with ALDOC and Brain
 Blood Antibodies  >5 publications with ALDOC and Blood
 Muscle Antibodies  >3 publications with ALDOC and Muscle
 Eye Antibodies  >3 publications with ALDOC and Eye
 Adipose Tissue Antibodies  >2 publications with ALDOC and Adipose Tissue
 Nerve Antibodies  >1 publications with ALDOC and Nerve
 Vascular Antibodies  >1 publications with ALDOC and Vascular
 Heart Antibodies  >1 publications with ALDOC and Heart
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