Rabbit Anti-TNFRSF10D Polyclonal Antibody – Cat# MBS643987

TNFRSF10D Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TNFRSF10D antibody detected the TNFRSF10D protein (arrow).

TNFRSF10D Antibody – Rabbit Polyclonal

Name: TNFRSF10D Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS643987
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643987

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TNFRSF10D, Polyclonal Antibody

Full Product Name

TNFRSF10D, CT (TNFRSF10D, DCR2, TRAILR4, TRUNDD, Tumor necrosis factor receptor superfamily member 10D, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TRAIL receptor with a truncated death domain, CD264)

Product Gene Name

anti-TNFRSF10D antibody

Product Synonym Names

Anti -TNFRSF10D, CT (TNFRSF10D, DCR2, TRAILR4, TRUNDD, Tumor necrosis factor receptor superfamily member 10D, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TRAIL receptor with a truncated death domain, CD264)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

41,823 Da

Chromosome Location

Chromosome: 8; NC_000008.10 (22993101..23021543, complement). Location: 8p21

OMIM

603614

3D Structure

ModBase 3D Structure for Q9UBN6

Immunogen

TNFRSF10D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-283 amino acids from the C-terminal region of human TNFRSF10D.

Product Categories/Family for anti-TNFRSF10D antibody

Antibodies; Abs to Apoptosis

Applications Tested/Suitable for anti-TNFRSF10D antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-TNFRSF10D antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-TNFRSF10D antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TNFRSF10D purchase

MBS643987 is an antibody targeting TNFRSF10D. Also known as TNFRSF10D, CT (TNFRSF10D, DCR2, TRAILR4, TRUNDD, Tumor necrosis factor receptor superfamily member 10D, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TRAIL receptor with a truncated death domain, CD264). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TNFRSF10D. It may not necessarily be applicable to this product.

NCBI GI #

22547108

NCBI GeneID

8793

NCBI Accession #

NP_003831.2

UniProt Primary Accession #

Q9UBN6

UniProt Secondary Accession #

Q9Y6Q4; B2R8W0

UniProt Related Accession #

Q9UBN6

GenBank Nucleotide #

NM_003840.4

NCBI Official Full Name

tumor necrosis factor receptor superfamily member 10D

NCBI Official Synonym Full Names

tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain

NCBI Official Symbol

TNFRSF10D

NCBI Official Synonym Symbols

DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4

UniProt Protein Name

Tumor necrosis factor receptor superfamily member 10D

UniProt Synonym Protein Names

Decoy receptor 2; DcR2; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4; TRAIL-R4; TRAIL receptor with a truncated death domain

Protein Family

Tumor necrosis factor receptor superfamily

UniProt Gene Name

TNFRSF10D

UniProt Synonym Gene Names

DCR2; TRAILR4; TRUNDD; DcR2; TRAIL receptor 4; TRAIL-R4

UniProt Entry Name

TR10D_HUMAN

NCBI Protein Information

tumor necrosis factor receptor superfamily member 10D; TRAIL receptor 4; decoy receptor 2; TNF receptor-related receptor for TRAIL; TRAIL receptor with a truncated death domain; TNF-related apoptosis-inducing ligand receptor 4

UniProt Comments for TNFRSF10D

TRAIL-R4: Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF- kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway. Widely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 8p21

Cellular Component: integral to membrane

Molecular Function: transmembrane receptor activity; TRAIL binding

Biological Process: apoptosis; signal transduction; negative regulation of apoptosis

Research Articles on TNFRSF10D

1. transcript levels of UCHL1, COL1A2, THBS1 and TNFRSF10D were inversely correlated with promoter methylation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TNFRSF10D antibody

Reference Product	PubMed Publications
TNFSF10 antibody	>49 publications with TNFRSF10D and TNFSF10
TNFRSF10B antibody	>48 publications with TNFRSF10D and TNFRSF10B
TNFRSF10A antibody	>20 publications with TNFRSF10D and TNFRSF10A
FADD antibody	>6 publications with TNFRSF10D and FADD
TP53 antibody	>2 publications with TNFRSF10D and TP53

Pathways associated with anti-TNFRSF10D antibody

Products by Pathway	Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Modulation And Signaling Pathway antibodies	Apoptosis Modulation And Signaling Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Direct P53 Effectors Pathway antibodies	Direct P53 Effectors Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram
Measles Pathway antibodies	Measles Pathway Diagram
Measles Pathway antibodies	Measles Pathway Diagram

Diseases associated with anti-TNFRSF10D antibody

Disease Name	Pubmed Publications
Necrosis Antibodies	>65 publications with TNFRSF10D and Necrosis
Neoplasms Antibodies	>50 publications with TNFRSF10D and Neoplasms
Prostatic Neoplasms Antibodies	>7 publications with TNFRSF10D and Prostatic Neoplasms
Neoplasms, Experimental Antibodies	>6 publications with TNFRSF10D and Neoplasms, Experimental
Breast Neoplasms Antibodies	>5 publications with TNFRSF10D and Breast Neoplasms
Adenocarcinoma Antibodies	>5 publications with TNFRSF10D and Adenocarcinoma
Inflammation Antibodies	>5 publications with TNFRSF10D and Inflammation
Ovarian Neoplasms Antibodies	>4 publications with TNFRSF10D and Ovarian Neoplasms
Colonic Neoplasms Antibodies	>4 publications with TNFRSF10D and Colonic Neoplasms
Cardiovascular Diseases Antibodies	>3 publications with TNFRSF10D and Cardiovascular Diseases

Organs/Tissues associated with anti-TNFRSF10D antibody

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>8 publications with TNFRSF10D and Prostate
Lung Antibodies	>4 publications with TNFRSF10D and Lung
Skin Antibodies	>2 publications with TNFRSF10D and Skin
Vascular Antibodies	>2 publications with TNFRSF10D and Vascular
Brain Antibodies	>2 publications with TNFRSF10D and Brain
Pancreas Antibodies	>2 publications with TNFRSF10D and Pancreas
Stomach Antibodies	>2 publications with TNFRSF10D and Stomach
Placenta Antibodies	>1 publications with TNFRSF10D and Placenta
Testis Antibodies	>1 publications with TNFRSF10D and Testis
Mammary Gland Antibodies	>1 publications with TNFRSF10D and Mammary Gland