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CENPB Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644002

This gene product is a highly conserved protein associated with the centromere. It is a DNA-binding protein containing a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CENPB, Polyclonal Antibody
Full Product Name
CENPB (Major Centromere Autoantigen B, Centromere Protein B, CENP-B)
Product Gene Name
Product Synonym Names
Anti -CENPB (Major Centromere Autoantigen B, Centromere Protein B, CENP-B)
Immunogen Sequence
MGPKRRQLTF REKSRIIQEV EENPDLRKGE IARRFNIPPS TLSTILKNKR AILASERKYG VASTCRKTNK LSPYDKLEGL LIAWFQQIRA AGLPVKGIIL KEKALRIAEE LGMDDFTASN GWLDRFRRRH GVVSCSGVAR ARARNAAPRT PAAPASPAAV PSEGSGGSTT GWRAREEQPP SVAEGYASQD VFSATETSLW YDFLPDQAAG LCGGDGRPRQ ATQRLSVLLC ANADGSEKLP PLVAGKSAKP RAGQAGLPCD YTANSKGGVT TQALAKYLKA LDTRMAAESR RVLLLAGRLA AQSLDTSGLR HVQLAFFPPG TVHPLERGVV QQVKGHYRQA MLLKAMAALE GQDPSGLQLG LTEALHFVAA AWQAVEPSDI AACFREAGFG GGPNATITTS LKSEGEEEEE EEEEEEEEEG EGEEEEEEGE EEEEEGGEGE ELGEEEEVEE EGDVDSDEEE EEDEESSSEG LEAEDWAQGV VEAGGSFGAY GAQEEAQCPT LHFLEGGEDS DSDSEEEDDE EEDDEDEDDD DDEEDGDEVP VPSFGEAMAY FAMVKRYLTS FPIDDRVQSH ILHLEHDLVH VTRKNHARQA GVRGLGHQS
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid.
Purity/Purification
Serum
Serum
Specificity
Recognizes human CENPB.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
65,381 Da
Chromosome Location
Chromosome: 2; NC_000068.7 (131177289..131180012, complement). Location: 2 F1; 2 63.29 cM
3D Structure
ModBase 3D Structure for P27790
Immunogen
Full length human CENPB, aa1-599 (AAH53847.1).

Product Categories/Family for anti-Cenpb antibody

Applications Tested/Suitable for anti-Cenpb antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-Cenpb antibody
Suitable for use in Western Blot and Immunoprecipitation.

Western Blot (WB) of anti-Cenpb antibody

Western Blot analysis of CENPB expression in transfected 293T cell line by CENPB polyclonal antibody. Lane 1: CENPB transfected lysate (65.2kD). Lane 2: Non-transfected lysate.
Rabbit Anti-CENPB Polyclonal Antibody – Cat# MBS644002

Immunoprecipitation (IP) of anti-Cenpb antibody

Immunoprecipitation of CENPB transfected lysate using CENPB rabbit polyclonal antibody and Protein A Magnetic Bead and immunoblotted with CENPB purified mouse polyclonal antibody.
Rabbit Anti-CENPB Polyclonal Antibody, Immunoprecipitation (IP) – Cat# MBS644002

Other Notes

Small volumes of anti-Cenpb antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cenpb purchase

MBS644002 is an antibody targeting Cenpb. Also known as CENPB (Major Centromere Autoantigen B, Centromere Protein B, CENP-B). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Cenpb. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Cenpb protein
NCBI Official Synonym Full Names
centromere protein B
NCBI Official Symbol
Cenpb
UniProt Protein Name
Major centromere autoantigen B
UniProt Synonym Protein Names
Centromere protein B
UniProt Gene Name
Cenpb
UniProt Synonym Gene Names
Cenp-b; CENP-B
UniProt Entry Name
CENPB_MOUSE
NCBI Protein Information
major centromere autoantigen B; CENP-B

UniProt Comments for Cenpb

CENPB: Interacts with centromeric heterochromatin in chromosomes and binds to a specific subset of alphoid satellite DNA, called the CENP-B box. May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes.

Protein type: DNA-binding

Cellular Component: chromosome; nucleus; chromosome, pericentric region

Molecular Function: DNA binding; nucleic acid binding; chromatin binding

Biological Process: regulation of transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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