Goat Anti-SLC47A2 Polyclonal Antibody – Cat# MBS644055

(0.1ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

SLC47A2 Antibody – Goat Polyclonal

Name: SLC47A2 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS644055
Price: 835 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644055

Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of… More details

$835 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SLC47A2, Polyclonal Antibody

Full Product Name

SLC47A2, ID (Multidrug and Toxin Extrusion Protein 2, MATE-2, hMATE-2, Kidney-specific H(+)/Organic Cation Antiporter, Solute Carrier Family 47 Member 2, MATE2)

Product Gene Name

anti-SLC47A2 antibody

Product Synonym Names

Anti -SLC47A2, ID (Multidrug and Toxin Extrusion Protein 2, MATE-2, hMATE-2, Kidney-specific H(+)/Organic Cation Antiporter, Solute Carrier Family 47 Member 2, MATE2)

Clonality

Polyclonal

Host

Goat

Species Reactivity

Human

Form/Format

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes human SLC47A2.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

65,085 Da

Chromosome Location

Chromosome: 17; NC_000017.10 (19581626..19622990, complement). Location: 17p11.2

OMIM

609833

3D Structure

ModBase 3D Structure for Q86VL8

Immunogen

Synthetic peptide corresponding to C-QRAESTATRPGPEK, from SLC47A2, at the internal region of the protein (NP_690872.2; NP_001093116.1).

Product Categories/Family for anti-SLC47A2 antibody

Antibodies; Abs to Ion Channel

Applications Tested/Suitable for anti-SLC47A2 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-SLC47A2 antibody

Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:32,000
Western Blot: 0.1-0.3ug/ml, human testis lysates observed on ~61kD bands

Other Notes

Small volumes of anti-SLC47A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC47A2 purchase

MBS644055 is an antibody targeting SLC47A2. Also known as SLC47A2, ID (Multidrug and Toxin Extrusion Protein 2, MATE-2, hMATE-2, Kidney-specific H(+)/Organic Cation Antiporter, Solute Carrier Family 47 Member 2, MATE2). Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC47A2. It may not necessarily be applicable to this product.

NCBI GI #

23271536

NCBI GeneID

146802

NCBI Accession #

AAH35288.1

UniProt Primary Accession #

Q86VL8

UniProt Secondary Accession #

Q63HJ9; Q8IV44; Q96NA1; A0JBX9; A0P8Z7

UniProt Related Accession #

Q86VL8

NCBI Official Full Name

SLC47A2 protein

NCBI Official Synonym Full Names

solute carrier family 47 (multidrug and toxin extrusion), member 2

NCBI Official Symbol

SLC47A2

NCBI Official Synonym Symbols

MATE2; MATE2K; MATE2-B; MATE2-K

UniProt Protein Name

Multidrug and toxin extrusion protein 2

UniProt Synonym Protein Names

Kidney-specific H(+)/organic cation antiporter; Solute carrier family 47 member 2

Protein Family

Multidrug and toxin extrusion protein

UniProt Gene Name

SLC47A2

UniProt Synonym Gene Names

MATE2; MATE-2; hMATE-2

UniProt Entry Name

S47A2_HUMAN

NCBI Protein Information

multidrug and toxin extrusion protein 2; MATE-2; hMATE-2; H+/organic cation antiporter; multidrug and toxin extrusion 2; solute carrier family 47, member 2; kidney-specific H(+)/organic cation antiporter

NCBI Summary for SLC47A2

This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for SLC47A2

SLC47A2: Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes. Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, SLC family; Transporter

Chromosomal Location of Human Ortholog: 17p11.2

Cellular Component: plasma membrane; integral to membrane

Molecular Function: drug transporter activity; antiporter activity

Biological Process: multidrug transport; transmembrane transport

Research Articles on SLC47A2

1. The effect of novel promoter variants in ... MATE2 on the pharmacokinetics and pharmacodynamics of metformin

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC47A2 antibody

Reference Product	PubMed Publications
SLC22A2 antibody	>4 publications with SLC47A2 and SLC22A2

Pathways associated with anti-SLC47A2 antibody

Products by Pathway	Pathway Diagram
SLC-mediated Transmembrane Transport Pathway antibodies	SLC-mediated Transmembrane Transport Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram
Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies	Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram

Diseases associated with anti-SLC47A2 antibody

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>1 publications with SLC47A2 and Kidney Diseases
Nervous System Diseases Antibodies	>1 publications with SLC47A2 and Nervous System Diseases

Organs/Tissues associated with anti-SLC47A2 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>7 publications with SLC47A2 and Kidney
Brain Antibodies	>1 publications with SLC47A2 and Brain