• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

RLBP1L2 (CLVS2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644072

Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RLBP1L2 (CLVS2), Polyclonal Antibody
Full Product Name
RLBP1L2, CT (CLVS2, C6orf212, C6orf213, RLBP1L2, Clavesin-2, Retinaldehyde-binding protein 1-like 2)
Product Gene Name
anti-CLVS2 antibody
Product Synonym Names
Anti -RLBP1L2, CT (CLVS2, C6orf212, C6orf213, RLBP1L2, Clavesin-2, Retinaldehyde-binding protein 1-like 2)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
38,000 Da
Chromosome Location
Chromosome: 6; NC_000006.11 (123317582..123385063). Location: 6q22.31
3D Structure
ModBase 3D Structure for Q5SYC1
Immunogen
RLBP1L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-287 amino acids from the C-terminal region of human RLBP1L2.

Product Categories/Family for anti-CLVS2 antibody

Antibodies; Abs to Binding Proteins
Applications Tested/Suitable for anti-CLVS2 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CLVS2 antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Western Blot (WB) of anti-CLVS2 antibody

RLBP1L2 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the RLBP1L2 antibody detected the RLBP1L2 protein (arrow).
Rabbit Anti-CLVS2 Polyclonal Antibody – Cat# MBS644072

Immunohistochemistry (IHC) of anti-CLVS2 antibody

RLBP1L2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RLBP1L2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-CLVS2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS644072

Other Notes

Small volumes of anti-CLVS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CLVS2 purchase

MBS644072 is an antibody targeting CLVS2. Also known as RLBP1L2, CT (CLVS2, C6orf212, C6orf213, RLBP1L2, Clavesin-2, Retinaldehyde-binding protein 1-like 2). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CLVS2. It may not necessarily be applicable to this product.

NCBI GI #
115527291
NCBI GeneID
134829
NCBI Accession #
AAI01378.1
UniProt Primary Accession #
Q5SYC1
UniProt Secondary Accession #
Q5SYC0; B3KTG5; B4DHL0; C8UZT4
UniProt Related Accession #
Q5SYC1
NCBI Official Full Name
Retinaldehyde binding protein 1-like 2
NCBI Official Synonym Full Names
clavesin 2
NCBI Official Symbol
CLVS2
NCBI Official Synonym Symbols
RLBP1L2; C6orf212; C6orf213; bA160A10.4
UniProt Protein Name
Clavesin-2
UniProt Synonym Protein Names
Retinaldehyde-binding protein 1-like 2
Protein Family
Clavesin
UniProt Gene Name
CLVS2
UniProt Synonym Gene Names
C6orf212; C6orf213; RLBP1L2
UniProt Entry Name
CLVS2_HUMAN
NCBI Protein Information
clavesin-2; retinaldehyde binding protein 1-like 2

NCBI Summary for CLVS2

This gene encodes a protein that belongs to the SEC14/CRAL-TRIO family of proteins. A similar protein in rat is thought to function in the endosomal pathway between early endosomes and mature lysosomes. [provided by RefSeq, Aug 2013]

UniProt Comments for CLVS2

RLBP1L2: Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 6q22.31

Cellular Component: clathrin-coated vesicle; early endosome membrane; trans-Golgi network; endosome

Molecular Function: transporter activity

Biological Process: transport; lysosome organization and biogenesis
Show more

Research Articles on CLVS2

1. Clavesin protein family appears to provide a unique neuron-specific regulation of late endosome/lysosome morphology.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000