Rabbit Anti-VDAC3 Polyclonal Antibody – Cat# MBS644104

VDAC3 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the VDAC3 antibody detected the VDAC3 protein (arrow).

VDAC3 Antibody – Rabbit Polyclonal

Name: VDAC3 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS644104
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644104

VDAC3 belongs to a group of mitochondrial membrane channels involved in translocation of adenine nucleotides through the outer membrane. These channels may also function as a mitochondrial binding site for hexokinase (see HK1; MIM 142600) and glycerol kinase… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

VDAC3, Polyclonal Antibody

Full Product Name

VDAC3, ID (VDAC3, Voltage-dependent anion-selective channel protein 3, Outer mitochondrial membrane protein porin 3)

Product Gene Name

anti-VDAC3 antibody

Product Synonym Names

Anti -VDAC3, ID (VDAC3, Voltage-dependent anion-selective channel protein 3, Outer mitochondrial membrane protein porin 3)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

30,659 Da

Chromosome Location

Chromosome: 8; NC_000008.10 (42249279..42263455). Location: 8p11.2

OMIM

610029

3D Structure

ModBase 3D Structure for Q9Y277

Immunogen

VDAC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-183 amino acids from the Central region of human VDAC3.

Product Categories/Family for anti-VDAC3 antibody

Antibodies; Abs to Mitochondrial Proteins

Applications Tested/Suitable for anti-VDAC3 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-VDAC3 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-VDAC3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VDAC3 purchase

MBS644104 is an antibody targeting VDAC3. Also known as VDAC3, ID (VDAC3, Voltage-dependent anion-selective channel protein 3, Outer mitochondrial membrane protein porin 3). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for VDAC3. It may not necessarily be applicable to this product.

NCBI GI #

208879465

NCBI GeneID

7419

NCBI Accession #

NP_001129166.1

UniProt Primary Accession #

Q9Y277

UniProt Secondary Accession #

Q9UIS0

UniProt Related Accession #

Q9Y277

GenBank Nucleotide #

NM_001135694.2

NCBI Official Full Name

voltage-dependent anion-selective channel protein 3 isoform 2

NCBI Official Synonym Full Names

voltage-dependent anion channel 3

NCBI Official Symbol

VDAC3

NCBI Official Synonym Symbols

VDAC-3; HD-VDAC3

UniProt Protein Name

Voltage-dependent anion-selective channel protein 3

UniProt Synonym Protein Names

Outer mitochondrial membrane protein porin 3

Protein Family

Mitochondrial outer membrane protein porin

UniProt Gene Name

VDAC3

UniProt Synonym Gene Names

VDAC-3; hVDAC3

UniProt Entry Name

VDAC3_HUMAN

NCBI Protein Information

voltage-dependent anion-selective channel protein 3; outer mitochondrial membrane protein porin 3

NCBI Summary for VDAC3

This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

UniProt Comments for VDAC3

VDAC3: a protein of the eukaryotic mitochondrial porin family. Forms a voltage-dependent anion channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. Two splice-variant isoforms have been described.

Protein type: Membrane protein, integral; Channel, misc.; Mitochondrial

Chromosomal Location of Human Ortholog: 8p11.2

Cellular Component: pore complex; mitochondrial outer membrane; mitochondrion; nucleus

Molecular Function: nucleotide binding; voltage-gated anion channel activity; porin activity

Biological Process: adenine transport; transmembrane transport; anion transport

Research Articles on VDAC3

1. a VDAC3-Mps1 module at the centrosome promotes ciliary disassembly during cell cycle entry.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-VDAC3 antibody

Reference Product	PubMed Publications
SLC25A5 antibody	>1 publications with VDAC3 and SLC25A5

Pathways associated with anti-VDAC3 antibody

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Hepatitis B Pathway antibodies	Hepatitis B Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
Parkinson's Disease Pathway antibodies	Parkinson's Disease Pathway Diagram
Viral Carcinogenesis Pathway antibodies	Viral Carcinogenesis Pathway Diagram
Viral Carcinogenesis Pathway antibodies	Viral Carcinogenesis Pathway Diagram

Diseases associated with anti-VDAC3 antibody

Disease Name	Pubmed Publications
Death Antibodies	>12 publications with VDAC3 and Death
Neoplasms Antibodies	>6 publications with VDAC3 and Neoplasms
Carcinoma, Hepatocellular Antibodies	>4 publications with VDAC3 and Carcinoma, Hepatocellular
Liver Diseases Antibodies	>3 publications with VDAC3 and Liver Diseases
Liver Neoplasms Antibodies	>3 publications with VDAC3 and Liver Neoplasms
Hypertension Antibodies	>1 publications with VDAC3 and Hypertension
Necrosis Antibodies	>1 publications with VDAC3 and Necrosis
Edema Antibodies	>1 publications with VDAC3 and Edema
Liver Neoplasms, Experimental Antibodies	>1 publications with VDAC3 and Liver Neoplasms, Experimental

Organs/Tissues associated with anti-VDAC3 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>8 publications with VDAC3 and Brain
Muscle Antibodies	>7 publications with VDAC3 and Muscle
Liver Antibodies	>5 publications with VDAC3 and Liver
Heart Antibodies	>4 publications with VDAC3 and Heart
Eye Antibodies	>4 publications with VDAC3 and Eye
Embryonic Tissue Antibodies	>4 publications with VDAC3 and Embryonic Tissue
Nerve Antibodies	>3 publications with VDAC3 and Nerve
Testis Antibodies	>2 publications with VDAC3 and Testis
Placenta Antibodies	>1 publications with VDAC3 and Placenta
Uterus Antibodies	>1 publications with VDAC3 and Uterus