• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

DAPP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644266

DAPP1 may act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K. More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DAPP1, Polyclonal Antibody
Full Product Name
DAPP1, CT (DAPP1, BAM32, Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide, B lymphocyte adapter protein Bam32, B-cell adapter molecule of 32kD)
Product Gene Name
anti-DAPP1 antibody
Product Synonym Names
Anti -DAPP1, CT (DAPP1, BAM32, Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide, B lymphocyte adapter protein Bam32, B-cell adapter molecule of 32kD)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
32,194 Da
Chromosome Location
Chromosome: 4; NC_000004.11 (100737957..100791347). Location: 4q25-q27
OMIM
605768
3D Structure
ModBase 3D Structure for Q9UN19
Immunogen
DAPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-275 amino acids from the C-terminal region of human DAPP1.

Product Categories/Family for anti-DAPP1 antibody

Antibodies; Abs to Adapter Proteins
Applications Tested/Suitable for anti-DAPP1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-DAPP1 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-DAPP1 antibody

DAPP1 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the DAPP1 antibody detected the DAPP1 protein (arrow).
Rabbit Anti-DAPP1 Polyclonal Antibody – Cat# MBS644266

Western Blot (WB) of anti-DAPP1 antibody

Western blot analysis of DAPP1 (arrow) using rabbit polyclonal DAPP1 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DAPP1 gene.
Rabbit Anti-DAPP1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS644266

Other Notes

Small volumes of anti-DAPP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DAPP1 purchase

MBS644266 is an antibody targeting DAPP1. Also known as DAPP1, CT (DAPP1, BAM32, Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide, B lymphocyte adapter protein Bam32, B-cell adapter molecule of 32kD). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DAPP1. It may not necessarily be applicable to this product.

NCBI GI #
15277836
NCBI GeneID
27071
NCBI Accession #
AAH12924.1
UniProt Primary Accession #
Q9UN19
UniProt Secondary Accession #
Q8TCK5; Q9UHF2
UniProt Related Accession #
Q9UN19
NCBI Official Full Name
DAPP1 protein
NCBI Official Synonym Full Names
dual adaptor of phosphotyrosine and 3-phosphoinositides
NCBI Official Symbol
DAPP1
NCBI Official Synonym Symbols
BAM32
UniProt Protein Name
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
UniProt Synonym Protein Names
B lymphocyte adapter protein Bam32; B-cell adapter molecule of 32 kDa
Protein Family
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
UniProt Gene Name
DAPP1
UniProt Synonym Gene Names
BAM32; hDAPP1
UniProt Entry Name
DAPP1_HUMAN
NCBI Protein Information
dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; hDAPP1; B-cell adapter molecule of 32 kDa; b lymphocyte adapter protein Bam32

UniProt Comments for DAPP1

DAPP1: an adaptor protein. Regulates antigen receptor signaling downstream of phosphatidylinositol 3-kinase.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 4q25-q27

Cellular Component: plasma membrane; cytosol

Molecular Function: phosphatidylinositol-3,4,5-triphosphate binding; phospholipid binding; phosphatidylinositol-3,4-bisphosphate binding

Biological Process: signal transduction; protein amino acid dephosphorylation
Show more

Research Articles on DAPP1

1. we propose a role for Bam32 in the signaling of MHC class I molecules in professional Ag-presenting DC for the regulation of CD8(+) T cell activation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DAPP1 antibody

 Reference Product  PubMed Publications
 SRC antibody  >16 publications with DAPP1 and SRC
 LYN antibody  >6 publications with DAPP1 and LYN
 BTK antibody  >5 publications with DAPP1 and BTK
 BLNK antibody  >1 publications with DAPP1 and BLNK
 LCK antibody  >1 publications with DAPP1 and LCK

Pathways associated with anti-DAPP1 antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Activates B Cell Receptor Leading To Generation Of Second Messengers Pathway antibodies  Antigen Activates B Cell Receptor Leading To Generation Of Second Messengers Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 BCR Signaling Pathway antibodies  BCR Signaling Pathway Diagram
 Class I PI3K Signaling Events Pathway antibodies  Class I PI3K Signaling Events Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Signaling By The B Cell Receptor (BCR) Pathway antibodies  Signaling By The B Cell Receptor (BCR) Pathway Diagram

Diseases associated with anti-DAPP1 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with DAPP1 and Neoplasms
 Carcinoma Antibodies  >1 publications with DAPP1 and Carcinoma
 Neoplasms, Experimental Antibodies  >1 publications with DAPP1 and Neoplasms, Experimental
 Hypertrophy Antibodies  >1 publications with DAPP1 and Hypertrophy
 Carcinoma, Hepatocellular Antibodies  >1 publications with DAPP1 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with DAPP1 and Liver Neoplasms
 Necrosis Antibodies  >1 publications with DAPP1 and Necrosis

Organs/Tissues associated with anti-DAPP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >3 publications with DAPP1 and Lymph Node
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000