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Hcg_1645727 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644365

The gene belongs to a family of genes encoding proteins containing a BTB domain and several kelch repeats. The BTB domain functions as a protein-protein interaction module, which includes an ability to self-associate or to interact with non-BTB… More details

$895 / 0.2 mL +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
hCG_1645727, Polyclonal Antibody
Full Product Name
hCG_1645727, CT (KBTBD13, Kelch repeat and BTB domain-containing protein 13)
Product Synonym Names
Anti -hCG_1645727, CT (KBTBD13, Kelch repeat and BTB domain-containing protein 13)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
hCG_1645727 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 416-446 amino acids from the C-terminal region of human hCG_1645727.
Applications Tested/Suitable for anti-hCG_1645727 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-hCG_1645727 antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Immunohistochemistry (IHC) of anti-hCG_1645727 antibody

hCG_1645727 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of hCG_1645727 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-Hcg_1645727 Polyclonal Antibody – Cat# MBS644365

Western Blot (WB) of anti-hCG_1645727 antibody

hCG_1645727 Antibody (C-term) western blot analysis in MDA-MB453,ZR-75-1,MCF-7 cell line lysates (35ug/lane).This demonstrates the hCG_1645727 antibody detected the hCG_1645727 protein (arrow).
Rabbit Anti-Hcg_1645727 Polyclonal Antibody, Western Blot (WB) – Cat# MBS644365

Other Notes

Small volumes of anti-hCG_1645727 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for hCG_1645727 purchase

MBS644365 is an antibody targeting hCG_1645727. Also known as hCG_1645727, CT (KBTBD13, Kelch repeat and BTB domain-containing protein 13). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for hCG_1645727. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
NCBI Official Full Name
hCG1645727

UniProt Comments for hCG_1645727

KBTBD13: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. Defects in KBTBD13 are the cause of nemaline myopathy type 6 (NEM6). A form of nemaline myopathy characterized by childhood onset of slowly progressive proximal muscle weakness, exercise intolerance, and slow movements with stiff muscles. Patients are unable to run or correct themselves from falling over.

Chromosomal Location of Human Ortholog: 15q22.31

Cellular Component: cytoplasm

Biological Process: protein ubiquitination

Disease: Nemaline Myopathy 6
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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