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NRGN Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644368

Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons… More details

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Product Overview

Online Datasheet in PDF
Product Name
NRGN, Polyclonal Antibody
Full Product Name
NRGN, ID (Neurogranin, Ng, RC3)
Product Gene Name
Product Synonym Names
Anti -NRGN, ID (Neurogranin, Ng, RC3)
Clonality
Polyclonal
Host
Goat
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human NRGN. Species sequence homology: mouse, bovine and canine.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
7,618 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (124609829..124617102). Location: 11q24
OMIM
602350
3D Structure
ModBase 3D Structure for Q92686
Immunogen
Synthetic peptide C-KIKSGERGRKG from an internal region of human Neurogranin.
Applications Tested/Suitable for anti-NRGN antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-NRGN antibody
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: ELISA: 1:8000
Western Blot: 0.1-0.3ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 3.75ug/ml

Immunohistochemistry (IHC) of anti-NRGN antibody

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Goat Anti-NRGN Polyclonal Antibody – Cat# MBS644368

Chemiluminescence of anti-NRGN antibody

NRGN antibody (0.1ug/ml) staining of Mouse Brain lysate (35ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-NRGN Polyclonal Antibody, Chemiluminescence – Cat# MBS644368

Other Notes

Small volumes of anti-NRGN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NRGN purchase

MBS644368 is an antibody targeting NRGN. Also known as NRGN, ID (Neurogranin, Ng, RC3). Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for NRGN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neurogranin
NCBI Official Synonym Full Names
neurogranin (protein kinase C substrate, RC3)
NCBI Official Symbol
NRGN
NCBI Official Synonym Symbols
RC3; hng
UniProt Protein Name
Neurogranin
UniProt Synonym Protein Names
RC3
Protein Family
UniProt Gene Name
NRGN
UniProt Synonym Gene Names
Ng
UniProt Entry Name
NEUG_HUMAN
NCBI Protein Information
neurogranin; ng; calmodulin-binding protein; protein kinase C substrate

UniProt Comments for NRGN

neurogranin: Acts as a third messenger substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium. Belongs to the neurogranin family.

Protein type: Cell development/differentiation

Chromosomal Location of Human Ortholog: 11q24

Cellular Component: intracellular

Molecular Function: calmodulin binding

Biological Process: nervous system development; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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