• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ESM1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644396

MBS644396 is an antibody targeting ESM1. Also known as ESM1 (Endothelial Cell-specific Molecule 1, ESM-1). Reactive in Human. Host: Mouse. May have potent implications in lung endothelial cell-leukocyte interactions. More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ESM1, Monoclonal Antibody
Full Product Name
ESM1 (Endothelial Cell-specific Molecule 1, ESM-1)
Product Gene Name
Product Synonym Names
Anti -ESM1 (Endothelial Cell-specific Molecule 1, ESM-1)
Immunogen Sequence
PSNGEDPFGE EFGICKDCPY GTFGMDCRET CNCQSGICDR GTGKCLKFPF FQYSVTKSSN RFVSLTEHDM ASGDGNIVRE EVVKENAAGS PVMRKWLNPR
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
6D4
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.4.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Concentration
0.5 mg/ml (lot specific)
Specificity
Recognizes human ESM1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Chromosome Location
Chromosome: 5; NC_000005.9 (54273695..54281414, complement). Location: 5q11.2
OMIM
601521
3D Structure
ModBase 3D Structure for Q9NQ30
Immunogen
Partial recombinant corresponding to aa85-185 from human ESM1 (NP_008967) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-ESM1 antibody

Applications Tested/Suitable for anti-ESM1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ESM1 antibody
Immunohistochemistry (Formalin fixed paraffin embedded):
3 ug/ml

Optimal dilutions should be determined by the researcher

Western Blot (WB) of anti-ESM1 antibody

Western Blot detection against Immunogen (37.11kD).
Mouse Anti-ESM1 Monoclonal Antibody – Cat# MBS644396

Western Blot (WB) of anti-ESM1 antibody

Western Blot analysis of ESM1 expression in transfected 293T cell line by ESM1 monoclonal antibody.|Lane 1: ESM1 transfected lysate (20.1kD).|Lane 2: Non-transfected lysate.
Mouse Anti-ESM1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS644396

Immunohistochemistry (IHC) of anti-ESM1 antibody

Immunoperoxidase of monoclonal antibody to ESM1 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3ug/ml].
Mouse Anti-ESM1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS644396

Testing Data of anti-ESM1 antibody

Detection limit for recombinant GST tagged ESM1 is ~0.03ng/ml as a capture antibody.
Mouse Anti-ESM1 Monoclonal Antibody, Testing Data – Cat# MBS644396

Other Notes

Small volumes of anti-ESM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ESM1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
endothelial cell-specific molecule 1 isoform b
NCBI Official Synonym Full Names
endothelial cell-specific molecule 1
NCBI Official Symbol
ESM1
NCBI Official Synonym Symbols
endocan
UniProt Protein Name
Endothelial cell-specific molecule 1
UniProt Gene Name
ESM1
UniProt Synonym Gene Names
ESM-1
UniProt Entry Name
ESM1_HUMAN
NCBI Protein Information
endothelial cell-specific molecule 1; ESM-1

NCBI Summary for ESM1

This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Show more

UniProt Comments for ESM1

ESM1: May have potent implications in lung endothelial cell- leukocyte interactions. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q11.2

Cellular Component: extracellular region

Molecular Function: integrin binding; insulin-like growth factor binding; hepatocyte growth factor receptor binding

Biological Process: positive regulation of cell proliferation; angiogenesis; sprouting angiogenesis; regulation of cell growth
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ESM1 antibody

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000