Mouse Anti-TWF2 Monoclonal Antibody – Cat# MBS644407

PTK9L monoclonal antibody Western Blot analysis of TWF2 expression in human liver.

PTK9L (TWF2) Antibody – Mouse Monoclonal

Name: TWF2 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS644407
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644407

The protein encoded by this gene was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin (PTK9), a conserved… More details

$880 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PTK9L (TWF2), Monoclonal Antibody

Full Product Name

PTK9L (TWF2, PTK9L, Twinfilin-2, A6-related Protein, Protein Tyrosine Kinase 9-like, Twinfilin-1-like Protein)

Product Gene Name

anti-TWF2 antibody

Product Synonym Names

Anti -PTK9L (TWF2, PTK9L, Twinfilin-2, A6-related Protein, Protein Tyrosine Kinase 9-like, Twinfilin-1-like Protein)

Immunogen Sequence

FAGYQKHLSS CAAPAPLTSA ERELQQIRIN EVKTEISVES KHQTLQGLAF PLQPEAQRAL QQLKQKMVNY IQMKLDLERE TIELVHTEPT DVAQLPSRVP

Clonality

Monoclonal

Isotype

IgG1,k

Clone Number

2B5

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human PTK9L.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

39,548 Da

Chromosome Location

Chromosome: 3; NC_000003.11 (52262626..52273183, complement). Location: 3p21.1

OMIM

607433

3D Structure

ModBase 3D Structure for Q6IBS0

Immunogen

Partial recombinant corresponding to aa131-230 from PTK9L (AAH00327) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-TWF2 antibody

Antibodies; Abs to Protein Kinases

Applications Tested/Suitable for anti-TWF2 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-TWF2 antibody

Suitable for use in ELISA and Western Blot.

Other Notes

Small volumes of anti-TWF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TWF2 purchase

MBS644407 is an antibody targeting TWF2. Also known as PTK9L (TWF2, PTK9L, Twinfilin-2, A6-related Protein, Protein Tyrosine Kinase 9-like, Twinfilin-1-like Protein). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for TWF2. It may not necessarily be applicable to this product.

NCBI GI #

49065466

NCBI GeneID

11344

NCBI Accession #

CAG38551.1

UniProt Primary Accession #

Q6IBS0

UniProt Secondary Accession #

Q9Y3F5

UniProt Related Accession #

Q6IBS0

NCBI Official Full Name

PTK9L

NCBI Official Synonym Full Names

twinfilin actin-binding protein 2

NCBI Official Symbol

TWF2

NCBI Official Synonym Symbols

A6r; A6RP; PTK9L; MSTP011

UniProt Protein Name

Twinfilin-2

UniProt Synonym Protein Names

A6-related protein; hA6RP; Protein tyrosine kinase 9-like; Twinfilin-1-like protein

Protein Family

Twinfilin

UniProt Gene Name

TWF2

UniProt Synonym Gene Names

PTK9L; hA6RP

UniProt Entry Name

TWF2_HUMAN

NCBI Protein Information

twinfilin-2; A6-related protein; twinfilin-1-like protein; twinfilin, actin-binding protein, homolog 2; protein tyrosine kinase 9-like (A6-related protein); PTK9L protein tyrosine kinase 9-like (A6-related protein)

UniProt Comments for TWF2

A6r: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia. Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 3p21.1

Cellular Component: stereocilium; cytoskeleton; growth cone; myofibril; perinuclear region of cytoplasm; lamellipodium; cytoplasm; filopodium

Molecular Function: actin monomer binding; phosphatidylinositol-4,5-bisphosphate binding; protein kinase C binding; ATP binding

Biological Process: cell projection organization and biogenesis; negative regulation of actin filament polymerization; sequestering of actin monomers; regulation of actin cytoskeleton organization and biogenesis; positive regulation of axon extension; regulation of microvillus length; barbed-end actin filament capping

Research Articles on TWF2

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-TWF2 antibody

Products by Pathway	Pathway Diagram
IGF1R Signaling Cascade Pathway antibodies	IGF1R Signaling Cascade Pathway Diagram
IRS-mediated Signalling Pathway antibodies	IRS-mediated Signalling Pathway Diagram
IRS-related Events Pathway antibodies	IRS-related Events Pathway Diagram
IRS-related Events Triggered By IGF1R Pathway antibodies	IRS-related Events Triggered By IGF1R Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Insulin Receptor Signalling Cascade Pathway antibodies	Insulin Receptor Signalling Cascade Pathway Diagram
MyD88 Dependent Cascade Initiated On Endosome Pathway antibodies	MyD88 Dependent Cascade Initiated On Endosome Pathway Diagram
PI3K Cascade Pathway antibodies	PI3K Cascade Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram

Organs/Tissues associated with anti-TWF2 antibody

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>2 publications with TWF2 and Muscle
Heart Antibodies	>2 publications with TWF2 and Heart