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RABGAP1 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644454

RABGAP1 may act as a GTPase-activating protein of RAB6A and play a role in microtubule nucleation by centrosome. It may participate in a RAB6A-mediated pathway involved in the metaphase-anaphase transition. More details

$880 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
RABGAP1, Polyclonal Antibody
Full Product Name
RABGAP1 (Rab GTPase-activating Protein 1, GAP and Centrosome-associated Protein, Rab6 GTPase-activating Protein GAPCenA)
Product Gene Name
anti-RABGAP1 antibody
Product Synonym Names
Anti -RABGAP1 (Rab GTPase-activating Protein 1, GAP and Centrosome-associated Protein, Rab6 GTPase-activating Protein GAPCenA)
Immunogen Sequence
MDDQPGEKEL VKRSQLDGEG DGPLSNQLSA SSTINPVPLV GLQKPEMSLP VKPGQGDSEA SSPFTPVADE DSVVFSKLTY LGCASVNAPR SEVEALRMMS ILRSQCQISL DVTLSVPNVS EGIVRLLDPQ TNTEIANYPI YKILFCVRGH DGTPESDCFA FTESHYNAEL FRIHVFRCEI QEAVSRILYS FATAFRRSAK QTPLSATAAP QTPDSDIFTF SVSLEIKEDD GKGYFSAVPK DKDRQCFKLR QGIDKKIVIY VQQTTNKELA IERCFGLLLS PGKDVRNSDM HLLDLESMGK SSDGKSYVIT GSWNPKSPHF QVVNEETPKD KVLFMTTAVD LVITEVQEPV RFLLETKVRV CSPNERLFWP FSKRSTTENF FLKLKQIKQR ERKNNTDTLY EVVCLESESE RERRKTTASP SVRLPQSGSQ SSVIPSPPED DEEEDNDEPL LSGSGDVSKE CAEKILETWG ELLSKWHLNL NVRPKQLSSL VRNGVPEALR GEVWQLLAGC HNNDHLVEKY RILITKESPQ DSAITRDINR TFPAHDYFKD TGGDGQDSLY KICKAYSVYD EEIGYCQGQS FLAAVLLLHM PEEQAFSVLV KIMFDYGLRE LFKQNFEDLH CKFYQLERLM QEYIPDLYNH FLDISLEAHM YASQWFLTLF TAKFPLYMVF HIIDLLLCEG ISVIFNVALG LLKTSKDDLL LTDFEGALKF FRVQLPKRYR SEENAKKLME LACNMKISQK KLKKYEKEYH TMREQQAQQE DPIERFEREN RRLQEANMRL EQENDDLAHE LVTSKIALRK DLDNAEEKAD ALNKELLMTK QKLIDAEEEK RRLEEESAQL KEMCRRELDK AESEIKKNSS IIGDYKQICS QLSERLEKQQ TANKVEIEKI RQKVDDCERC REFFNKEGRV KGISSTKEVL DEDTDEEKET LKNQLREMEL ELAQTKLQLV EAECKIQDLE HHLGLALNEV QAAKKTWFNR TLSSIKTATG VQGKETC
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human RABGAP1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
121,737 Da
Chromosome Location
Chromosome: 9; NC_000009.11 (125703288..125867147). Location: 9q34.11
3D Structure
ModBase 3D Structure for Q9Y3P9
Immunogen
Full length human RABGAP1, aa1-997 (NP_036329.2).

Product Categories/Family for anti-RABGAP1 antibody

Antibodies; Abs to GTPase; Rab; Ras; Rho Proteins
Applications Tested/Suitable for anti-RABGAP1 antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-RABGAP1 antibody
Suitable for use in Immunofluorescence and Western Blot.
Dilution: Immunofluorescence: 10ug/ml

Western Blot (WB) of anti-RABGAP1 antibody

Western Blot analysis of RABGAP1 expression in transfected 293T cell line by RABGAP1 polyclonal antibody. Lane 1: RABGAP1 transfected lysate (109.67kD). Lane 2: Non-transfected lysate.
Mouse Anti-RABGAP1 Polyclonal Antibody – Cat# MBS644454

Immunofluorescence (IF) of anti-RABGAP1 antibody

Immunofluorescence of purified antibody to RABGAP1 on HeLa cell. [antibody concentration 10ug/ml]
Mouse Anti-RABGAP1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS644454

Other Notes

Small volumes of anti-RABGAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RABGAP1 purchase

MBS644454 is an antibody targeting RABGAP1. Also known as RABGAP1 (Rab GTPase-activating Protein 1, GAP and Centrosome-associated Protein, Rab6 GTPase-activating Protein GAPCenA). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for RABGAP1. It may not necessarily be applicable to this product.

NCBI GI #
32451579
NCBI GeneID
23637
NCBI Accession #
AAH54492.1
UniProt Primary Accession #
Q9Y3P9
UniProt Secondary Accession #
Q05CW2; Q6ZMY1; Q9HA28; Q9P0E2; Q9UG67; B9A6L2
UniProt Related Accession #
Q9Y3P9
NCBI Official Full Name
RABGAP1 protein
NCBI Official Synonym Full Names
RAB GTPase activating protein 1
NCBI Official Symbol
RABGAP1
NCBI Official Synonym Symbols
GAPCENA; TBC1D11; RP11-123N4.2
UniProt Protein Name
Rab GTPase-activating protein 1
UniProt Synonym Protein Names
GAP and centrosome-associated protein; Rab6 GTPase-activating protein GAPCenA
Protein Family
Rab GTPase-activating protein
UniProt Gene Name
RABGAP1
UniProt Entry Name
RBGP1_HUMAN
NCBI Protein Information
rab GTPase-activating protein 1; TBC1 domain family, member 11; GAP and centrosome-associated protein; rab6 GTPase-activating protein GAPCenA; Rab6 GTPase activating protein, GAPCenA; rab6 GTPase activating protein (GAP and centrosome-associated)

UniProt Comments for RABGAP1

RABGAP1: May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase- anaphase transition. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Autophagy; GAPs, Rab; GAPs

Chromosomal Location of Human Ortholog: 9q34.11

Cellular Component: centrosome; microtubule associated complex; cytosol

Molecular Function: tubulin binding; protein binding; DNA binding; GTPase activator activity; Rab GTPase binding

Biological Process: cell cycle; positive regulation of GTPase activity
Show more

Research Articles on RABGAP1

1. suggest that EPI64A and B, which are ubiquitously expressed members of the EPI64 subfamily, inactivate Ras and certain Rabs at the periphery of cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RABGAP1 antibody

 Reference Product  PubMed Publications
 CARM1 antibody  >1 publications with RABGAP1 and CARM1
 RAB6A antibody  >1 publications with RABGAP1 and RAB6A

Diseases associated with anti-RABGAP1 antibody

 Disease Name  Pubmed Publications
 Death Antibodies  >1 publications with RABGAP1 and Death

Organs/Tissues associated with anti-RABGAP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >1 publications with RABGAP1 and Ovary
 Bone Antibodies  >1 publications with RABGAP1 and Bone
 Kidney Antibodies  >1 publications with RABGAP1 and Kidney
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