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SUDS3 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644543

MBS644543 is an antibody targeting SUDS3. Also known as SUDS3 (Suppressor of Defective Silencing 3 Protein Homolog, SDS3, Sin3 Histone Deacetylase Corepressor Complex Component SDS3, 45 kDa Sin3-associated Polypeptide, SAP45). Reactive in Human. Host: Mouse. More details

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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SUDS3, Polyclonal Antibody
Full Product Name
SUDS3 (Suppressor of Defective Silencing 3 Protein Homolog, SDS3, Sin3 Histone Deacetylase Corepressor Complex Component SDS3, 45 kDa Sin3-associated Polypeptide, SAP45)
Product Gene Name
anti-SUDS3 antibody
Product Synonym Names
Anti -SUDS3 (Suppressor of Defective Silencing 3 Protein Homolog, SDS3, Sin3 Histone Deacetylase Corepressor Complex Component SDS3, 45 kDa Sin3-associated Polypeptide, SAP45)
Immunogen Sequence
MSAAGLLAPA PAQAGAPPAP EYYPEEDEEL ESAEDDERSC RGRESDEDTE DASETDLAKH DEEDYVEMKE QMYQDKLASL KRQLQQLQEG TLQEYQKRMK KLDQQYKERI RNAELFLQLE TEQVERNYIK EKKAAVKEFE DKKVELKENL IAELEEKKKM IENEKLTMEL TGDSMEVKPI MTRKLRRRPN DPVPIPDKRR KPAPAQLNYL LTDEQIMEDL RTLNKLKSPK RPASPSSPEH LPATPAESPA QRFEARIEDG KLYYDKRWYH KSQAIYLESK DNQKLSCVIS SVGANEIWVR KTSDSTKMRI YLGQLQRGLF VIRRRSAA
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human SUDS3.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
38,136 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (118814358..118855840). Location: 12q24.23
OMIM
608250
3D Structure
ModBase 3D Structure for Q9H7L9
Immunogen
Full length human SUDS3, aa1-328 (NP_071936.2).

Product Categories/Family for anti-SUDS3 antibody

Antibodies; Abs to Transcription Factors
Applications Tested/Suitable for anti-SUDS3 antibody
Western Blot (WB)
Application Notes for anti-SUDS3 antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-SUDS3 antibody

SUDS3 polyclonal antibody. Western Blot analysis of SUDS3 expression in Hela NE.
Mouse Anti-SUDS3 Polyclonal Antibody – Cat# MBS644543

Western Blot (WB) of anti-SUDS3 antibody

Western Blot analysis of SUDS3 expression in transfected 293T cell line by SUDS3 polyclonal antibody. Lane 1: SUDS3 transfected lysate (36.08kD). Lane 2: Non-transfected lysate.
Mouse Anti-SUDS3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS644543

Other Notes

Small volumes of anti-SUDS3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SUDS3. It may not necessarily be applicable to this product.

NCBI GI #
75677351
NCBI GeneID
64426
NCBI Accession #
NP_071936.2
UniProt Primary Accession #
Q9H7L9
UniProt Secondary Accession #
Q4KMQ5; Q8N6H0; Q9H8D2
UniProt Related Accession #
Q9H7L9
GenBank Nucleotide #
NM_022491.2
NCBI Official Full Name
sin3 histone deacetylase corepressor complex component SDS3
NCBI Official Synonym Full Names
suppressor of defective silencing 3 homolog (S. cerevisiae)
NCBI Official Symbol
SUDS3
NCBI Official Synonym Symbols
SDS3; SAP45
UniProt Protein Name
Sin3 histone deacetylase corepressor complex component SDS3
UniProt Synonym Protein Names
45 kDa Sin3-associated polypeptide; Suppressor of defective silencing 3 protein homolog
Protein Family
Sin3 histone deacetylase corepressor complex component
UniProt Gene Name
SUDS3
UniProt Synonym Gene Names
SAP45; SDS3
UniProt Entry Name
SDS3_HUMAN
NCBI Protein Information
sin3 histone deacetylase corepressor complex component SDS3; sin3A-associated protein, 45kDa; 45 kDa Sin3-associated polypeptide; suppressor of defective silencing 3 protein homolog

NCBI Summary for SUDS3

SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008]

UniProt Comments for SUDS3

SDS3: component of the Sin3/histone deacetylase corepressor complex. Essential for pericentric heterochromatin formation and chromosome segregation in mammalian cells.

Protein type: Helicase

Chromosomal Location of Human Ortholog: 12q24.23

Cellular Component: nucleoplasm; Sin3 complex; cytoplasm; nucleus

Molecular Function: protein binding; enzyme binding; protein homodimerization activity; histone deacetylase binding; histone deacetylase activity

Biological Process: establishment and/or maintenance of chromatin architecture; substantia nigra development; transcription, DNA-dependent; negative regulation of gene expression, epigenetic; positive regulation of apoptosis; apoptosis; histone deacetylation; gene expression; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; regulation of gene expression, epigenetic
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Research Articles on SUDS3

1. studies reveal that loss of FAM60A or another component of the Sin3 complex, SDS3, leads to a change in cell morphology and an increase in cell migration

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SUDS3 antibody

 Reference Product  PubMed Publications
 HDAC1 antibody  >1 publications with SUDS3 and HDAC1

Diseases associated with anti-SUDS3 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1 publications with SUDS3 and Neoplasms
 Anemia Antibodies  >1 publications with SUDS3 and Anemia
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