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USP49 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644552

MBS644552 is an antibody targeting USP49. Also known as USP49, NT (USP49, Ubiquitin carboxyl-terminal hydrolase 49, Deubiquitinating enzyme 49, Ubiquitin thioesterase 49, Ubiquitin-specific-processing protease 49). Reactive in Human, Mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
USP49, Polyclonal Antibody
Full Product Name
USP49, NT (USP49, Ubiquitin carboxyl-terminal hydrolase 49, Deubiquitinating enzyme 49, Ubiquitin thioesterase 49, Ubiquitin-specific-processing protease 49)
Product Gene Name
Product Synonym Names
Anti -USP49, NT (USP49, Ubiquitin carboxyl-terminal hydrolase 49, Deubiquitinating enzyme 49, Ubiquitin thioesterase 49, Ubiquitin-specific-processing protease 49)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human, mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
79,198 Da
Chromosome Location
Chromosome: 6; NC_000006.11 (41757634..41863099, complement). Location: 6p21
3D Structure
ModBase 3D Structure for Q70CQ1
Immunogen
USP49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human USP49.

Product Categories/Family for anti-USP49 antibody

Applications Tested/Suitable for anti-USP49 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-USP49 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-USP49 antibody

USP49 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the USP49 antibody detected the USP49 protein (arrow).
Rabbit Anti-USP49 Polyclonal Antibody – Cat# MBS644552

Western Blot (WB) of anti-USP49 antibody

USP49 Antibody (N-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the USP49 antibody detected USP49 protein (arrow).
Rabbit Anti-USP49 Polyclonal Antibody, Western Blot (WB) – Cat# MBS644552

Other Notes

Small volumes of anti-USP49 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for USP49. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ubiquitin carboxyl-terminal hydrolase 49
NCBI Official Synonym Full Names
ubiquitin specific peptidase 49
NCBI Official Symbol
USP49
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 49
UniProt Synonym Protein Names
Deubiquitinating enzyme 49; Ubiquitin thioesterase 49; Ubiquitin-specific-processing protease 49
UniProt Gene Name
USP49
UniProt Entry Name
UBP49_HUMAN
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase 49; ubiquitin thioesterase 49; deubiquitinating enzyme 49; ubiquitin thiolesterase 49; ubiquitin specific protease 49; ubiquitin-specific-processing protease 49

UniProt Comments for USP49

USP49: Belongs to the peptidase C19 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.19.12; Ubiquitin-specific protease; Protease

Chromosomal Location of Human Ortholog: 6p21

Cellular Component: nucleus

Molecular Function: protein binding; zinc ion binding; histone binding; cysteine-type endopeptidase activity; ubiquitin-specific protease activity

Biological Process: nuclear mRNA splicing, via spliceosome; proteasomal ubiquitin-dependent protein catabolic process; protein deubiquitination
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-USP49 antibody

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