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GSTK1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644556

GSTK1 encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of… More details

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Product Overview

Online Datasheet in PDF
Product Name
GSTK1, Polyclonal Antibody
Full Product Name
GSTK1, ID (GSTK1, Glutathione S-transferase kappa 1, GST 13-13, GST class-kappa, GSTK1-1, Glutathione S-transferase subunit 13)
Product Gene Name
anti-GSTK1 antibody
Product Synonym Names
Anti -GSTK1, ID (GSTK1, Glutathione S-transferase kappa 1, GST 13-13, GST class-kappa, GSTK1-1, Glutathione S-transferase subunit 13)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human, mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
25,497 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (142960506..142966222). Location: 7q34
OMIM
602321
3D Structure
ModBase 3D Structure for Q9Y2Q3
Immunogen
GSTK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99~128 amino acids from the Central region of human GSTK1.

Product Categories/Family for anti-GSTK1 antibody

Antibodies; Abs to GST
Applications Tested/Suitable for anti-GSTK1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-GSTK1 antibody
Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Flow Cytometry: 1:10-50

Western Blot (WB) of anti-GSTK1 antibody

Western blot analysis of GSTK1 Antibody (Center) in mouse liver tissue lysates (35ug/lane). GSTK1 (arrow) was detected using the purified Pab.
Rabbit Anti-GSTK1 Polyclonal Antibody – Cat# MBS644556

Immunohistochemistry (IHC) of anti-GSTK1 antibody

GSTK1 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GSTK1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-GSTK1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS644556

Flow Cytometry (FC/FACS) of anti-GSTK1 antibody

GSTK1 Antibody (Center) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-GSTK1 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS644556

Other Notes

Small volumes of anti-GSTK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSTK1 purchase

MBS644556 is an antibody targeting GSTK1. Also known as GSTK1, ID (GSTK1, Glutathione S-transferase kappa 1, GST 13-13, GST class-kappa, GSTK1-1, Glutathione S-transferase subunit 13). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GSTK1. It may not necessarily be applicable to this product.

NCBI GI #
219842335
NCBI GeneID
373156
NCBI Accession #
NP_001137153.1
UniProt Primary Accession #
Q9Y2Q3
UniProt Secondary Accession #
Q6P4H0; Q7Z520; Q9P1S4; B4DIH1; B4DSY2
UniProt Related Accession #
Q9Y2Q3
GenBank Nucleotide #
NM_001143681.1
NCBI Official Full Name
glutathione S-transferase kappa 1 isoform d
NCBI Official Synonym Full Names
glutathione S-transferase kappa 1
NCBI Official Symbol
GSTK1
NCBI Official Synonym Symbols
GST; GST13; hGSTK1; GSTK1-1; GST13-13; GST 13-13
UniProt Protein Name
Glutathione S-transferase kappa 1
UniProt Synonym Protein Names
GST 13-13; GST class-kappa; GSTK1-1; hGSTK1; Glutathione S-transferase subunit 13
Protein Family
Glutathione S-transferase
UniProt Gene Name
GSTK1
UniProt Synonym Gene Names
hGSTK1
UniProt Entry Name
GSTK1_HUMAN
NCBI Protein Information
glutathione S-transferase kappa 1; GST class-kappa; glutathione S-transferase k1; glutathione S-transferase subunit 13 homolog

NCBI Summary for GSTK1

This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]
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UniProt Comments for GSTK1

GSTK1: Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB). Belongs to the GST superfamily. Kappa family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Xenobiotic Metabolism - metabolism by cytochrome P450; Xenobiotic Metabolism - drug metabolism - cytochrome P450; EC 2.5.1.18; Mitochondrial; Transferase; Other Amino Acids Metabolism - glutathione

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: membrane; intracellular membrane-bound organelle; mitochondrial matrix; mitochondrial inner membrane; peroxisome; intracellular

Molecular Function: glutathione transferase activity; protein disulfide oxidoreductase activity; glutathione peroxidase activity; receptor binding

Biological Process: glutathione metabolic process; epithelial cell differentiation
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Research Articles on GSTK1

1. drug resistance in three strains of tumor cells is associated with significant increase in hGSTP1 and hGSTA4 gene expression, whereas increased hGSTK1 gene expression was detected only in resistant erythroleukemia and mammary adenocarcinoma cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GSTK1 antibody

 Reference Product  PubMed Publications
 GSTO1 antibody  >3 publications with GSTK1 and GSTO1
 GSTM2 antibody  >2 publications with GSTK1 and GSTM2
 GSTM5 antibody  >2 publications with GSTK1 and GSTM5
 GSTA1 antibody  >2 publications with GSTK1 and GSTA1
 GSTA3 antibody  >2 publications with GSTK1 and GSTA3
 GSTA4 antibody  >2 publications with GSTK1 and GSTA4
 GSTZ1 antibody  >2 publications with GSTK1 and GSTZ1
 MGST3 antibody  >1 publications with GSTK1 and MGST3

Pathways associated with anti-GSTK1 antibody

 Products by Pathway  Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Metabolism Of Xenobiotics By Cytochrome P450 Pathway antibodies  Metabolism Of Xenobiotics By Cytochrome P450 Pathway Diagram
 Metabolism Of Xenobiotics By Cytochrome P450 Pathway antibodies  Metabolism Of Xenobiotics By Cytochrome P450 Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram

Diseases associated with anti-GSTK1 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >3 publications with GSTK1 and Inflammation
 Neoplasms Antibodies  >2 publications with GSTK1 and Neoplasms
 Kidney Diseases Antibodies  >2 publications with GSTK1 and Kidney Diseases
 Breast Neoplasms Antibodies  >1 publications with GSTK1 and Breast Neoplasms
 Ovarian Neoplasms Antibodies  >1 publications with GSTK1 and Ovarian Neoplasms
 Brain Diseases Antibodies  >1 publications with GSTK1 and Brain Diseases
 Poisoning Antibodies  >1 publications with GSTK1 and Poisoning
 Liver Diseases Antibodies  >1 publications with GSTK1 and Liver Diseases
 Nervous System Diseases Antibodies  >1 publications with GSTK1 and Nervous System Diseases
 Lung Diseases Antibodies  >1 publications with GSTK1 and Lung Diseases

Organs/Tissues associated with anti-GSTK1 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >10 publications with GSTK1 and Liver
 Blood Antibodies  >7 publications with GSTK1 and Blood
 Kidney Antibodies  >6 publications with GSTK1 and Kidney
 Muscle Antibodies  >4 publications with GSTK1 and Muscle
 Heart Antibodies  >4 publications with GSTK1 and Heart
 Lung Antibodies  >3 publications with GSTK1 and Lung
 Brain Antibodies  >3 publications with GSTK1 and Brain
 Intestine Antibodies  >3 publications with GSTK1 and Intestine
 Stomach Antibodies  >2 publications with GSTK1 and Stomach
 Vascular Antibodies  >2 publications with GSTK1 and Vascular
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