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NACA2 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644618

Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
NACAL (NACA2), Polyclonal Antibody
Full Product Name
NACAL (NACA2, Nascent Polypeptide-associated Complex Subunit alpha-2, Alpha-NAC-like, Hom s 2.01, Nascent Polypeptide-associated Complex Subunit alpha-like, NAC-alpha-like)
Product Gene Name
Product Synonym Names
Anti -NACAL (NACA2, Nascent Polypeptide-associated Complex Subunit alpha-2, Alpha-NAC-like, Hom s 2.01, Nascent Polypeptide-associated Complex Subunit alpha-like, NAC-alpha-like)
Immunogen Sequence
MPGEATETVP ATEQELPQSQ AETGSGTASD SGESVPGIEE QDSTQTTTQK AWLVAAAEID EEPVGKAKQS RSEKRARKAM SKLGLLQVTG VTRVTIWKSK NILFVITKLD VYKSPASDAY IVFGEAKIQD LSQQAQLAAA EKFRVQGEAV GNIQENTQTP TVQEESEEEE VDETGVEVKD VKLVMSQANV SRAKAVRALK NNSNDIVNAI MELTV
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human NACAL.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
23,223 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (59667794..59668563, complement). Location: 17q23.2
OMIM
609274
3D Structure
ModBase 3D Structure for Q9H009
Immunogen
Full length human NACAL, aa1-215 (NP_954984.1).

Product Categories/Family for anti-NACA2 antibody

Applications Tested/Suitable for anti-NACA2 antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-NACA2 antibody
Suitable for use in Immunofluorescence and Western Blot.
Dilution: Immunofluorescence: 10ug/ml

Western Blot (WB) of anti-NACA2 antibody

Western Blot analysis of NACA2 expression in transfected 293T cell line by NACA2 polyclonal antibody. Lane 1: NACAL transfected lysate (23.65kD). Lane 2: Non-transfected lysate.
Mouse Anti-NACA2 Polyclonal Antibody – Cat# MBS644618

Immunofluorescence (IF) of anti-NACA2 antibody

Immunofluorescence of purified antibody to NACAL on HepG2 cell. [antibody concentration 10ug/ml].
Mouse Anti-NACA2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS644618

Other Notes

Small volumes of anti-NACA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NACA2 purchase

MBS644618 is an antibody targeting NACA2. Also known as NACAL (NACA2, Nascent Polypeptide-associated Complex Subunit alpha-2, Alpha-NAC-like, Hom s 2.01, Nascent Polypeptide-associated Complex Subunit alpha-like, NAC-alpha-like). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for NACA2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nascent polypeptide-associated complex subunit alpha-2
NCBI Official Synonym Full Names
nascent polypeptide-associated complex alpha subunit 2
NCBI Official Symbol
NACA2
NCBI Official Synonym Symbols
ANAC; NACAL
UniProt Protein Name
Nascent polypeptide-associated complex subunit alpha-2
UniProt Synonym Protein Names
Alpha-NAC-like; Hom s 2.01; Nascent polypeptide-associated complex subunit alpha-like
UniProt Gene Name
NACA2
UniProt Synonym Gene Names
NACAL; NAC-alpha-like
UniProt Entry Name
NACA2_HUMAN
NCBI Protein Information
nascent polypeptide-associated complex subunit alpha-2; alpha-NAC protein; hom s 2.01 protein; IgE autoantigen alpha-nascent polypeptide-associated complex; nascent polypeptide-associated complex, alpha polypeptide, 2

UniProt Comments for NACA2

NACA2: Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). Belongs to the NAC-alpha family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 17q23.2

Cellular Component: cytoplasm; nucleus

Biological Process: protein transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-NACA2 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >4 publications with NACA2 and Kidney
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