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Fucokinase (FUK) Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644647

Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides. More details

$880 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Fucokinase (FUK), Polyclonal Antibody
Full Product Name
Fucokinase (L-fucose Kinase, FUK, 1110046B12Rik, FLJ39408)
Product Gene Name
anti-FUK antibody
Product Synonym Names
Anti -Fucokinase (L-fucose Kinase, FUK, 1110046B12Rik, FLJ39408)
Immunogen Sequence
MEQPKGVDWT VIILTCQYKD SVQVFQRELE VRQKREQIPA GTLLLAVEDP EKRVGSGGAT LNALLVAAEH LSARAGFTVV TSDVLHSAWI LILHMGRDFP FDDCGRAFTC LPVENPEAPV EALVCNLDCL LDIMTYRLGP GSPPGVWVCS TDMLLSVPAN PGISWDSFRG ARVIALPGSP AYAQNHGVYL TDPQGLVLDI YYQGTEAEIQ RCVRPDGRVP LVSGVVFFSV ETAERLLATH VSPPLDACTY LGLDSGARPV QLSLFFDILH CMAENVTRED FLVGRPPELG QGDADVAGYL QSARAQLWRE LRDQPLTMAY VSSGSYSYMT SSASEFLLSL TLPGAPGAQI VHSQVEEQQL LAAGSSVVSC LLEGPVQLGP GSVLQHCHLQ GPIHIGAGCL VTGLDTAHSK ALHGRELRDL VLQGHHTRLH GSPGHAFTLV GRLDSWERQG AGTYLNVPWS EFFKRTGVRA WDLWDPETLP AEYCLPSARL FPVLHPSREL GPQDLLWMLD HQEDGGEALR AWRASWRLSW EQLQPCLDRA ATLASRRDLF FRQALHKARH VLEARQDLSL RPLIWAAVRE GCPGPLLATL DQVAAGAGDP GVAARALACV ADVLGCMAEG RGGLRSGPAA NPEWMRPFSY LECGDLAAGV EALAQERDKW LSRPALLVRA ARHYEGAGQI LIRQAVMSAQ HFVSTEQVEL PGPGQWVVAE CPARVDFSGG WSDTPPLAYE LGGAVLGLAV RVDGRRPIGA RARRIPEPEL WLAVGPRQDE MTVKIVCRCL ADLRDYCQPH APGALLKAAF ICAGIVHVHS ELQLSEQLLR TFGGGFELHT WSELPHGSGL GTSSILAGTA LAALQRAAGR VVGTEALIHA VLHLEQVLTT GGGWQDQVGG LMPGIKVGRS RAQLPLKVEV EEVTVPEGFV QKLNDHLLLV YTGKTRLARN LLQDVLRSWY ARLPAVVQNA HSLVRQTEEC AEGFRQGSLP LLGQCLTSYW EQKKLMAPGC EPLTVRRMMD VLAPHVHGQS LAGAGGGGFL YLLTKEPQQK EALEAVLAKT EGLGNYSIHL VEVDTQGLSL KLLGTEASTC CPFP
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human FUK.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
117,623 Da
Chromosome Location
Chromosome: 16; NC_000016.9 (70488498..70514177). Location: 16q22.1
OMIM
608675
3D Structure
ModBase 3D Structure for Q8N0W3
Immunogen
Full length human FUK, aa1-1084 (NP_659496.2).

Product Categories/Family for anti-FUK antibody

Antibodies; Abs to Protein Kinases
Applications Tested/Suitable for anti-FUK antibody
Western Blot (WB)
Application Notes for anti-FUK antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-FUK antibody

Western Blot analysis of FUK expression in transfected 293T cell line by FUK polyclonal antibody. Lane1: FUK transfected lysate (119.24kD). Lane2: Non-transfected lysate.
Mouse Anti-FUK Polyclonal Antibody – Cat# MBS644647

Other Notes

Small volumes of anti-FUK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FUK purchase

MBS644647 is an antibody targeting FUK. Also known as Fucokinase (L-fucose Kinase, FUK, 1110046B12Rik, FLJ39408). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for FUK. It may not necessarily be applicable to this product.

NCBI GI #
66363704
NCBI GeneID
197258
NCBI Accession #
AAH32542.2
UniProt Primary Accession #
Q8N0W3
UniProt Secondary Accession #
Q5PSM3; Q5XKL6; Q6ZRA0; Q96MT9
UniProt Related Accession #
Q8N0W3
NCBI Official Full Name
Fucokinase
NCBI Official Synonym Full Names
fucokinase
NCBI Official Symbol
FUK
NCBI Official Synonym Symbols
1110046B12Rik
UniProt Protein Name
L-fucose kinase
Protein Family
L-fucose kinase
UniProt Gene Name
FUK
UniProt Synonym Gene Names
Fucokinase
UniProt Entry Name
FUK_HUMAN
NCBI Protein Information
L-fucose kinase

NCBI Summary for FUK

The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq, Jul 2008]
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UniProt Comments for FUK

FUK: Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides. Belongs to the GHMP kinase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Kinase, other; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - fructose and mannose; EC 2.7.1.52

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: cytoplasm

Molecular Function: fucokinase activity; ATP binding

Biological Process: phosphorylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FUK antibody

 Reference Product  PubMed Publications
 FPGT antibody  >1 publications with FUK and FPGT

Pathways associated with anti-FUK antibody

 Products by Pathway  Pathway Diagram
 Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies  Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
 Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies  Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
 GDP-L-fucose Biosynthesis II (from L-fucose) Pathway antibodies  GDP-L-fucose Biosynthesis II (from L-fucose) Pathway Diagram

Diseases associated with anti-FUK antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with FUK and Neoplasms
 Disease Models, Animal Antibodies  >2 publications with FUK and Disease Models, Animal
 Inflammation Antibodies  >2 publications with FUK and Inflammation
 Immune System Diseases Antibodies  >1 publications with FUK and Immune System Diseases
 Immunologic Deficiency Syndromes Antibodies  >1 publications with FUK and Immunologic Deficiency Syndromes
 Cardiovascular Diseases Antibodies  >1 publications with FUK and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >1 publications with FUK and Neoplasms, Experimental
 Skin Neoplasms Antibodies  >1 publications with FUK and Skin Neoplasms

Organs/Tissues associated with anti-FUK antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with FUK and Blood
 Eye Antibodies  >2 publications with FUK and Eye
 Kidney Antibodies  >2 publications with FUK and Kidney
 Brain Antibodies  >2 publications with FUK and Brain
 Lymph Antibodies  >1 publications with FUK and Lymph
 Skin Antibodies  >1 publications with FUK and Skin
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