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TAF1L Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644650

May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced. More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TAF1L, Monoclonal Antibody
Full Product Name
TAF1L (Transcription Initiation Factor TFIID Subunit 1-like, Transcription Initiation Factor TFIID 210kD Subunit, TAF(II)210, TBP-associated Factor 210kD, TBP-associated Factor 1-like, MGC134910)
Product Gene Name
anti-TAF1L antibody
Product Synonym Names
Anti -TAF1L (Transcription Initiation Factor TFIID Subunit 1-like, Transcription Initiation Factor TFIID 210kD Subunit, TAF(II)210, TBP-associated Factor 210kD, TBP-associated Factor 1-like, MGC134910)
Immunogen Sequence
NIVTQKMMAV PDSWPFHHPV NKKFVPDYYK MIVNPVDLET IRKNISKHKY QSRESFLDDV NLILANSVKY NGPESQYTKT AQEIVNICYQ TITEYDEHLT QLEKDICTAK
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
1E12
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human TAF1L.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
207,302 Da
Chromosome Location
Chromosome: 9; NC_000009.11 (32629452..32635667, complement). Location: 9p21.1
OMIM
607798
3D Structure
ModBase 3D Structure for Q8IZX4
Immunogen
Partial recombinant protein corresponding to aa1532-1642 from human TAF1L (NP_722516) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-TAF1L antibody

Antibodies; Abs to Binding Proteins
Applications Tested/Suitable for anti-TAF1L antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TAF1L antibody
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 1ug/ml

Western Blot (WB) of anti-TAF1L antibody

Western Blot detection against Immunogen (38.21kD).
Mouse Anti-TAF1L Monoclonal Antibody – Cat# MBS644650

Immunohistochemistry (IHC) of anti-TAF1L antibody

Immunoperoxidase of monoclonal antibody to TAF1L on formalin-fixed paraffin-embedded human testis. [antibody concentration 1ug/ml].
Mouse Anti-TAF1L Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS644650

Testing Data of anti-TAF1L antibody

Detection limit for recombinant GST tagged TAF1L is ~0.03ng/ml as a capture antibody.
Mouse Anti-TAF1L Monoclonal Antibody, Testing Data – Cat# MBS644650

Other Notes

Small volumes of anti-TAF1L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TAF1L purchase

MBS644650 is an antibody targeting TAF1L. Also known as TAF1L (Transcription Initiation Factor TFIID Subunit 1-like, Transcription Initiation Factor TFIID 210kD Subunit, TAF(II)210, TBP-associated Factor 210kD, TBP-associated Factor 1-like, MGC134910). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for TAF1L. It may not necessarily be applicable to this product.

NCBI GI #
24429572
NCBI GeneID
138474
NCBI Accession #
NP_722516.1
UniProt Primary Accession #
Q8IZX4
UniProt Secondary Accession #
Q0VG57
UniProt Related Accession #
Q8IZX4
GenBank Nucleotide #
NM_153809.2
NCBI Official Full Name
transcription initiation factor TFIID subunit 1-like
NCBI Official Synonym Full Names
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
NCBI Official Symbol
TAF1L
NCBI Official Synonym Symbols
TAF2A2
UniProt Protein Name
Transcription initiation factor TFIID subunit 1-like
UniProt Synonym Protein Names
TAF(II)210; TBP-associated factor 1-like; TBP-associated factor 210 kDa; Transcription initiation factor TFIID 210 kDa subunit
Protein Family
Transcription initiation factor
UniProt Gene Name
TAF1L
UniProt Entry Name
TAF1L_HUMAN
NCBI Protein Information
transcription initiation factor TFIID subunit 1-like; TAF(II)210; TBP-associated factor 1-like; TBP-associated factor 210 kDa; TBP-associated factor RNA polymerase 1-like; transcription initiation factor TFIID 210 kDa subunit

NCBI Summary for TAF1L

This locus is intronless, and apparently arose in the primate lineage from retrotransposition of the transcript from the multi-exon TAF1 locus on the X chromosome. The gene is expressed in male germ cells, and the product has been shown to function interchangeably with the TAF1 product. [provided by RefSeq, Aug 2009]
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UniProt Comments for TAF1L

TAF1L: May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced. Belongs to the TAF1 family.

Protein type: Transcription initiation complex; Kinase, protein; Protein kinase, atypical; DNA-binding; ATYPICAL group; TAF1 family

Chromosomal Location of Human Ortholog: 9p21.1

Cellular Component: nucleoplasm; transcription factor TFIID complex

Molecular Function: protein serine/threonine kinase activity; histone acetyltransferase activity; DNA binding; TATA-binding protein binding

Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; viral reproduction; positive regulation of transcription, DNA-dependent; RNA elongation from RNA polymerase II promoter; gene expression; histone acetylation; male meiosis; protein amino acid phosphorylation
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Research Articles on TAF1L

1. Arose by retroposition of a processed TAF(II)250 mRNA during primate evolution, replaces its function only in male meiosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-TAF1L antibody

 Products by Pathway  Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
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