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SFRS2B (SRSF8) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644664

The SR (serine/arginine-rich) family contains a number of phosphoproteins that function as essential and alternative splicing factors. The SR family of proteins is characterized by the presence of a ribonucleoprotein (RNP)-type RNA binding motif and a… More details

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Product Overview

Online Datasheet in PDF
Product Name
SFRS2B (SRSF8), Polyclonal Antibody
Full Product Name
SFRS2B, NT (SRSF8, SFRS2B, SRP46, Serine/arginine-rich splicing factor 8, Pre-mRNA-splicing factor SRP46, Splicing factor, arginine/serine-rich 2B)
Product Gene Name
Product Synonym Names
Anti -SFRS2B, NT (SRSF8, SFRS2B, SRP46, Serine/arginine-rich splicing factor 8, Pre-mRNA-splicing factor SRP46, Splicing factor, arginine/serine-rich 2B)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human, mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
32,288 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (94800041..94804387). Location: 11q22
OMIM
603269
3D Structure
ModBase 3D Structure for Q9BRL6
Immunogen
SFRS2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human SFRS2B.
Applications Tested/Suitable for anti-SRSF8 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-SRSF8 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-SRSF8 antibody

SFRS2B Antibody (N-term ) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the SFRS2B antibody detected the SFRS2B protein (arrow).
Rabbit Anti-SRSF8 Polyclonal Antibody – Cat# MBS644664

Western Blot (WB) of anti-SRSF8 antibody

SFRS2B Antibody (N-term ) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the SFRS2B antibody detected the SFRS2B protein (arrow).
Rabbit Anti-SRSF8 Polyclonal Antibody, Western Blot (WB) – Cat# MBS644664

Other Notes

Small volumes of anti-SRSF8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SRSF8 purchase

MBS644664 is an antibody targeting SRSF8. Also known as SFRS2B, NT (SRSF8, SFRS2B, SRP46, Serine/arginine-rich splicing factor 8, Pre-mRNA-splicing factor SRP46, Splicing factor, arginine/serine-rich 2B). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SRSF8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
serine/arginine-rich splicing factor 8
NCBI Official Synonym Full Names
serine/arginine-rich splicing factor 8
NCBI Official Symbol
SRSF8
NCBI Official Synonym Symbols
DSM-1; SRP46; SFRS2B
UniProt Protein Name
Serine/arginine-rich splicing factor 8
UniProt Synonym Protein Names
Pre-mRNA-splicing factor SRP46; Splicing factor SRp46; Splicing factor, arginine/serine-rich 2B
UniProt Gene Name
SRSF8
UniProt Synonym Gene Names
SFRS2B; SRP46; Splicing factor SRp46
UniProt Entry Name
SRSF8_HUMAN
NCBI Protein Information
serine/arginine-rich splicing factor 8; SR splicing factor 8; splicing factor SRp46; pre-mRNA-splicing factor SRP46; splicing factor, arginine/serine-rich 2B; splicing factor, arginine/serine-rich, 46kD

NCBI Summary for SRSF8

This gene encodes a member of a family of proteins containing a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. The encoded protein functions as a pre-mRNA splicing factor. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
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UniProt Comments for SRSF8

SRp46: Involved in pre-mRNA alternative splicing. Belongs to the splicing factor SR family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 11q22

Cellular Component: nucleus

Molecular Function: protein binding; nucleotide binding

Biological Process: RNA splicing; mRNA processing
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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