• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

WDR36 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644702

MBS644702 is an antibody targeting WDR36. Also known as WDR36 (WD Repeat-containing Protein 36, T-cell Activation WD Repeat-containing Protein, TAWDRP, TA-WDRP, GLC1G, UTP21). Reactive in Human. Host: Mouse. More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
WDR36, Monoclonal Antibody
Full Product Name
WDR36 (WD Repeat-containing Protein 36, T-cell Activation WD Repeat-containing Protein, TAWDRP, TA-WDRP, GLC1G, UTP21)
Product Gene Name
anti-WDR36 antibody
Product Synonym Names
Anti -WDR36 (WD Repeat-containing Protein 36, T-cell Activation WD Repeat-containing Protein, TAWDRP, TA-WDRP, GLC1G, UTP21)
Immunogen Sequence
SGIETELRSL SPDCGGSIEV MQSFLKMIGM MLDRKRDFEL AQAYLALFLK LHLKMLPSEP VLLEEITNLS SQVEENWTHL QSLFNQSMCI LNYLKSALL
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
1D6
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human WDR36.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
105,322 Da
Chromosome Location
Chromosome: 5; NC_000005.9 (110427870..110466200). Location: 5q22.1
OMIM
609669
3D Structure
ModBase 3D Structure for Q8NI36
Immunogen
Partial recombinant protein corresponding to aa853-952 from human WDR36 (NP_644810) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-WDR36 antibody

Antibodies; Abs to WD Repeat Proteins
Applications Tested/Suitable for anti-WDR36 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-WDR36 antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-WDR36 antibody

Western Blot detection against Immunogen (37kD).
Mouse Anti-WDR36 Monoclonal Antibody – Cat# MBS644702

Testing Data of anti-WDR36 antibody

Detection limit for recombinant GST tagged WDR36 is ~0.3ng/ml as a capture antibody.
Mouse Anti-WDR36 Monoclonal Antibody, Testing Data – Cat# MBS644702

Other Notes

Small volumes of anti-WDR36 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for WDR36. It may not necessarily be applicable to this product.

NCBI GI #
21281677
NCBI GeneID
134430
NCBI Accession #
NP_644810.1
UniProt Primary Accession #
Q8NI36
UniProt Secondary Accession #
Q8N1Q2; A2RUS4
UniProt Related Accession #
Q8NI36
GenBank Nucleotide #
NM_139281.2
NCBI Official Full Name
WD repeat-containing protein 36
NCBI Official Synonym Full Names
WD repeat domain 36
NCBI Official Symbol
WDR36
NCBI Official Synonym Symbols
GLC1G; UTP21; TAWDRP; TA-WDRP
UniProt Protein Name
WD repeat-containing protein 36
UniProt Synonym Protein Names
T-cell activation WD repeat-containing protein
Protein Family
WD repeat-containing protein
UniProt Gene Name
WDR36
UniProt Synonym Gene Names
TA-WDRP
UniProt Entry Name
WDR36_HUMAN
NCBI Protein Information
WD repeat-containing protein 36; T-cell activation WD repeat protein; T-cell activation WD repeat-containing protein

NCBI Summary for WDR36

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG). [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for WDR36

WDR36: Involved in T-cell activation and highly co-regulated with IL2. Defects in WDR36 are the cause of primary open angle glaucoma type 1G (GLC1G). Primary open angle glaucoma (POAG) is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place.

Protein type: Nucleolus

Chromosomal Location of Human Ortholog: 5q22.1

Cellular Component: small subunit processome; nucleolus

Biological Process: retinal homeostasis; visual perception; response to stimulus; regulation of axon extension; rRNA processing

Disease: Glaucoma 1, Open Angle, G
Show more

Research Articles on WDR36

1. Single nucleotide polymorphism in the WDR36 gene, rs10038177 (c.710+30C>T), was found to be strongly associated with the high tension glaucoma cases, but not with controls in the East Indian population.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-WDR36 antibody

 Reference Product  PubMed Publications
 PWP2 antibody  >1 publications with WDR36 and PWP2
 STIP1 antibody  >1 publications with WDR36 and STIP1

Pathways associated with anti-WDR36 antibody

 Products by Pathway  Pathway Diagram
 Ribosome Biogenesis In Eukaryotes Pathway antibodies  Ribosome Biogenesis In Eukaryotes Pathway Diagram
 Ribosome Biogenesis In Eukaryotes Pathway antibodies  Ribosome Biogenesis In Eukaryotes Pathway Diagram

Diseases associated with anti-WDR36 antibody

 Disease Name  Pubmed Publications
 Hypertension Antibodies  >4 publications with WDR36 and Hypertension
 Asthma Antibodies  >3 publications with WDR36 and Asthma
 Cardiovascular Diseases Antibodies  >1 publications with WDR36 and Cardiovascular Diseases
 Inflammation Antibodies  >1 publications with WDR36 and Inflammation

Organs/Tissues associated with anti-WDR36 antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >42 publications with WDR36 and Eye
 Blood Antibodies  >7 publications with WDR36 and Blood
 Brain Antibodies  >2 publications with WDR36 and Brain
 Heart Antibodies  >1 publications with WDR36 and Heart
 Liver Antibodies  >1 publications with WDR36 and Liver
 Muscle Antibodies  >1 publications with WDR36 and Muscle
 Pancreas Antibodies  >1 publications with WDR36 and Pancreas
 Placenta Antibodies  >1 publications with WDR36 and Placenta
 Lung Antibodies  >1 publications with WDR36 and Lung
 Kidney Antibodies  >1 publications with WDR36 and Kidney
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000