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FHOD3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644790

FHOD3 is a novel member of the formin homology family playing an important role in regulation of the actin cytoskeleton. It contains aDD (diaphanous auto regulatory) domain, an FH1 (formin homology 1) domain, an FH2 (formin homology 2) domain and a GBD/FH3… More details

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Product Overview

Online Datasheet in PDF
Product Name
FHOD3, Polyclonal Antibody
Full Product Name
FHOD3 (FH1/FH2 Domain-containing Protein 3, Formactin-2, Formin Homolog Overexpressed in Spleen 2, hFHOS2, FHOS2, KIAA1695)
Product Gene Name
Product Synonym Names
Anti -FHOD3 (FH1/FH2 Domain-containing Protein 3, Formactin-2, Formin Homolog Overexpressed in Spleen 2, hFHOS2, FHOS2, KIAA1695)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Bovine, Canine, Chicken, Equine, Human, Mouse
Form/Format
Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human FHOD3. Species Crossreactivity: chicken, canine, equine, bovine, mouse, opossum.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
158,613 Da
Chromosome Location
Chromosome: 18; NC_000018.9 (33877677..34360019). Location: 18q12
OMIM
609691
3D Structure
ModBase 3D Structure for Q2V2M9
Immunogen
Synthetic peptide corresponding to aa1250-1300 of human FHOD3 (CRA_d).
Applications Tested/Suitable for anti-FHOD3 antibody
Immunohistochemistry (IHC)
Application Notes for anti-FHOD3 antibody
Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry (formalin fixed paraffin embedded): 15ug/ml

Immunohistochemistry (IHC) of anti-FHOD3 antibody

Immunohistochemical analysis of FHOD3 in formalin-fixed, paraffin-embedded mouse brain tissue using an isotype control (top left) and MBS644790(bottom, right) at 15ug/ml.
Rabbit Anti-FHOD3 Polyclonal Antibody – Cat# MBS644790

Other Notes

Small volumes of anti-FHOD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FHOD3 purchase

MBS644790 is an antibody targeting FHOD3. Also known as FHOD3 (FH1/FH2 Domain-containing Protein 3, Formactin-2, Formin Homolog Overexpressed in Spleen 2, hFHOS2, FHOS2, KIAA1695). Reactive in Bovine, Canine, Chicken, Equine, Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FHOD3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
FH1/FH2 domain-containing protein 3 isoform 1
NCBI Official Synonym Full Names
formin homology 2 domain containing 3
NCBI Official Symbol
FHOD3
NCBI Official Synonym Symbols
FHOS2; Formactin2
UniProt Protein Name
FH1/FH2 domain-containing protein 3
UniProt Synonym Protein Names
Formactin-2; Formin homolog overexpressed in spleen 2
UniProt Gene Name
FHOD3
UniProt Synonym Gene Names
FHOS2; KIAA1695; hFHOS2
UniProt Entry Name
FHOD3_HUMAN
NCBI Protein Information
FH1/FH2 domain-containing protein 3; hFHOS2; formactin-2; formin homolog overexpressed in spleen 2

NCBI Summary for FHOD3

Proteins that contain formin (FMN1; MIM 136535) homology (FH) domains, such as FHOD3, play a role in regulation of the actin cytoskeleton (Kanaya et al., 2005 [PubMed 15966898]).[supplied by OMIM, Apr 2010]

UniProt Comments for FHOD3

FHOD3: Actin-organizing protein that may cause stress fiber formation together with cell elongation. Belongs to the formin homology family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 18q12

Cellular Component: Z disc; striated muscle thin filament

Molecular Function: protein binding; actin binding

Biological Process: negative regulation of actin filament polymerization; actin filament network formation; cardiac myofibril assembly; sarcomere organization
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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