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RAB5C Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644822

Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
RAB5C, Polyclonal Antibody
Full Product Name
RAB5C, CT (RAB5C, RABL, Ras-related protein Rab-5C, L1880, RAB5L)
Product Gene Name
Product Synonym Names
Anti -RAB5C, CT (RAB5C, RABL, Ras-related protein Rab-5C, L1880, RAB5L)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
23,483 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (40276994..40307062, complement). Location: 17q21.2
OMIM
604037
3D Structure
ModBase 3D Structure for P51148
Immunogen
RAB5C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-207 amino acids from the C-terminal region of human RAB5C.
Applications Tested/Suitable for anti-RAB5C antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-RAB5C antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Western Blot (WB) of anti-RAB5C antibody

RAB5C Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the RAB5C antibody detected the RAB5C protein (arrow).
Rabbit Anti-RAB5C Polyclonal Antibody – Cat# MBS644822

Immunohistochemistry (IHC) of anti-RAB5C antibody

RAB5C Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RAB5C Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-RAB5C Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS644822

Other Notes

Small volumes of anti-RAB5C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB5C purchase

MBS644822 is an antibody targeting RAB5C. Also known as RAB5C, CT (RAB5C, RABL, Ras-related protein Rab-5C, L1880, RAB5L). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB5C. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
RAB5C
NCBI Official Synonym Full Names
RAB5C, member RAS oncogene family
NCBI Official Symbol
RAB5C
NCBI Official Synonym Symbols
RABL; L1880; RAB5L; RAB5CL
UniProt Protein Name
Ras-related protein Rab-5C
UniProt Synonym Protein Names
L1880; RAB5L
Protein Family
UniProt Gene Name
RAB5C
UniProt Synonym Gene Names
RABL
UniProt Entry Name
RAB5C_HUMAN
NCBI Protein Information
ras-related protein Rab-5C; RAB5C, member of RAS oncogene family

UniProt Comments for RAB5C

RAB5C: Protein transport. Probably involved in vesicular traffic. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein, monomeric, Rab; G protein; Motility/polarity/chemotaxis; G protein, monomeric

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: intracellular membrane-bound organelle; lysosomal membrane; early endosome membrane; endocytic vesicle; early endosome; plasma membrane; melanosome; lipid particle

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding

Biological Process: intracellular protein transport; metabolic process; regulation of endocytosis; plasma membrane to endosome transport; Rab protein signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RAB5C antibody

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