Mouse Anti-UCK2 Monoclonal Antibody – Cat# MBS645098

Immunoprecipitation of UCK2 transfected lysate using UCK2 monoclonal antibody and Protein A Magnetic Bead and immunoblotted with UCK2 rabbit polyclonal antibody.

UCK2 Antibody – Mouse Monoclonal

Name: UCK2 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS645098
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645098

MBS645098 is an antibody targeting UCK2. Also known as UCK2 (Uridine-cytidine Kinase 2, UCK 2, Cytidine Monophosphokinase 2, Testis-specific Protein TSA903, Uridine Monophosphokinase 2, UMPK). Reactive in Human. Host: Mouse. More details

$880 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

UCK2, Monoclonal Antibody

Full Product Name

UCK2 (Uridine-cytidine Kinase 2, UCK 2, Cytidine Monophosphokinase 2, Testis-specific Protein TSA903, Uridine Monophosphokinase 2, UMPK)

Product Gene Name

anti-UCK2 antibody

Product Synonym Names

Anti -UCK2 (Uridine-cytidine Kinase 2, UCK 2, Cytidine Monophosphokinase 2, Testis-specific Protein TSA903, Uridine Monophosphokinase 2, UMPK)

Immunogen Sequence

MAGDSEQTLQ NHQQPNGGEP FLIGVSGGTA SGKSSVCAKI VQLLGQNEVD YRQKQVVILS QDSFYRVLTS EQKAKALKGQ FNFDHPDAFD NELILKTPKE ITEGKTVQIP VYDFVSHSRK EETVTVYPAD VVLFEGILAF YSQEVRDLFQ MKLFVDTDAD TRLSRRVLRD ISERGRDLEQ ILSQYITFVK PAFEEFCLPT KKYADVIIPR GADNLVAINL IVQHIQDILN GGPSKRQTNG CLNGYTPSRK R*ASESSSRP H

Clonality

Monoclonal

Isotype

IgG2a,k

Clone Number

1G12

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human UCK2.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

29,299 Da

Chromosome Location

Chromosome: 1; NC_000001.10 (165796732..165880855). Location: 1q23

OMIM

609329

3D Structure

ModBase 3D Structure for Q9BZX2

Immunogen

Full length recombinant corresponding to aa1-261 from human UCK2 (AAH02906) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-UCK2 antibody

Antibodies; Abs to Protein Kinases

Applications Tested/Suitable for anti-UCK2 antibody

ELISA (EL/EIA), Immunoprecipitation (IP)

Application Notes for anti-UCK2 antibody

Suitable for use in ELISA and Immunoprecipitation.

Other Notes

Small volumes of anti-UCK2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UCK2. It may not necessarily be applicable to this product.

NCBI GI #

18699734

NCBI GeneID

7371

NCBI Accession #

NP_036606.2

UniProt Primary Accession #

Q9BZX2

UniProt Secondary Accession #

Q5VV91; Q7KZV3; Q92528; Q96KG5; Q9BU42

UniProt Related Accession #

Q9BZX2

GenBank Nucleotide #

NM_012474.4

NCBI Official Full Name

uridine-cytidine kinase 2

NCBI Official Synonym Full Names

uridine-cytidine kinase 2

NCBI Official Symbol

UCK2

NCBI Official Synonym Symbols

UK; UMPK; TSA903

UniProt Protein Name

Uridine-cytidine kinase 2

UniProt Synonym Protein Names

Cytidine monophosphokinase 2; Testis-specific protein TSA903; Uridine monophosphokinase 2

Protein Family

Uridine-cytidine kinase

UniProt Gene Name

UCK2

UniProt Synonym Gene Names

UMPK; UCK 2

UniProt Entry Name

UCK2_HUMAN

NCBI Protein Information

uridine-cytidine kinase 2; uridine kinase; uridine monophosphokinase 2; cytidine monophosphokinase 2; uridine monophosphate kinase; testis-specific protein TSA903

NCBI Summary for UCK2

This gene encodes a pyrimidine ribonucleoside kinase. The encoded protein (EC 2.7.1.48) catalyzes phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively.[provided by RefSeq, Oct 2010]

UniProt Comments for UCK2

UCK2: Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4- thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)- benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5- methylcytidine, and N(4)-anisoylcytidine. Belongs to the uridine kinase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Kinase, other; EC 2.7.1.48; Xenobiotic Metabolism - drug metabolism - other enzymes; Nucleotide Metabolism - pyrimidine

Chromosomal Location of Human Ortholog: 1q23

Cellular Component: intracellular membrane-bound organelle; cytosol

Molecular Function: uridine kinase activity; nucleoside kinase activity; ATP binding

Biological Process: pyrimidine base metabolic process; nucleobase, nucleoside and nucleotide metabolic process; CMP salvage; feeding behavior; pyrimidine nucleoside salvage; response to axon injury; phosphorylation

Research Articles on UCK2

1. The mechanism of phosphate transfer in UCK2 is shown to be concerted, and is accompanied by concerted proton transfer from the 5'-hydroxyl to a conserved active site aspartic acid that serves as a catalytic base

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-UCK2 antibody

Reference Product	PubMed Publications
UMPS antibody	>1 publications with UCK2 and UMPS

Pathways associated with anti-UCK2 antibody

Products by Pathway	Pathway Diagram
Drug Metabolism - Other Enzymes Pathway antibodies	Drug Metabolism - Other Enzymes Pathway Diagram
Drug Metabolism - Other Enzymes Pathway antibodies	Drug Metabolism - Other Enzymes Pathway Diagram
Fluoropyrimidine Activity Pathway antibodies	Fluoropyrimidine Activity Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Nucleotides Pathway antibodies	Metabolism Of Nucleotides Pathway Diagram
Pyrimidine Metabolism Pathway antibodies	Pyrimidine Metabolism Pathway Diagram
Pyrimidine Metabolism Pathway antibodies	Pyrimidine Metabolism Pathway Diagram
Pyrimidine Metabolism Pathway antibodies	Pyrimidine Metabolism Pathway Diagram
Pyrimidine Salvage Reactions Pathway antibodies	Pyrimidine Salvage Reactions Pathway Diagram
Pyrimidine Ribonucleosides Salvage I Pathway antibodies	Pyrimidine Ribonucleosides Salvage I Pathway Diagram

Diseases associated with anti-UCK2 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>5 publications with UCK2 and Neoplasms
Carcinoma Antibodies	>2 publications with UCK2 and Carcinoma
Neoplasms, Experimental Antibodies	>2 publications with UCK2 and Neoplasms, Experimental
Neoplasm Metastasis Antibodies	>1 publications with UCK2 and Neoplasm Metastasis
Disease Models, Animal Antibodies	>1 publications with UCK2 and Disease Models, Animal
Adenocarcinoma Antibodies	>1 publications with UCK2 and Adenocarcinoma
Breast Neoplasms Antibodies	>1 publications with UCK2 and Breast Neoplasms
Cell Transformation, Neoplastic Antibodies	>1 publications with UCK2 and Cell Transformation, Neoplastic
Liver Neoplasms Antibodies	>1 publications with UCK2 and Liver Neoplasms

Organs/Tissues associated with anti-UCK2 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>4 publications with UCK2 and Blood
Placenta Antibodies	>4 publications with UCK2 and Placenta
Liver Antibodies	>3 publications with UCK2 and Liver
Testis Antibodies	>3 publications with UCK2 and Testis
Stomach Antibodies	>1 publications with UCK2 and Stomach
Kidney Antibodies	>1 publications with UCK2 and Kidney
Skin Antibodies	>1 publications with UCK2 and Skin
Intestine Antibodies	>1 publications with UCK2 and Intestine
Eye Antibodies	>1 publications with UCK2 and Eye
Heart Antibodies	>1 publications with UCK2 and Heart