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HSPH1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645124

HSPH1 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. This protein inhibits HSPA8/HSC70 ATPase and chaperone activities. More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HSPH1, Polyclonal Antibody
Full Product Name
HSPH1, ID (HSPH1, HSP105, HSP110, KIAA0201, Heat shock protein 105kD, Antigen NY-CO-25, Heat shock 110kD protein)
Product Gene Name
Product Synonym Names
Anti -HSPH1, ID (HSPH1, HSP105, HSP110, KIAA0201, Heat shock protein 105kD, Antigen NY-CO-25, Heat shock 110kD protein)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Purified
Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
96,726 Da
Chromosome Location
Chromosome: 12; AC_000169.1 (29820740..29844227). Location: chromosome: 12
3D Structure
ModBase 3D Structure for Q0IIM3
Immunogen
HSPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557~586 amino acids from the Center region of human HSPH1.
Applications Tested/Suitable for anti-HSPH1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-HSPH1 antibody
Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:50-100
Immunohistochemistry: 1:50-100
Flow Cytometry: 1:10-50

Western Blot (WB) of anti-HSPH1 antibody

Western blot analysis of HSPH1 Antibody (Center) in K562 cell line lysates (35ug/lane). HSPH1 (arrow) was detected using the purified Pab.
Rabbit Anti-HSPH1 Polyclonal Antibody – Cat# MBS645124

Immunohistochemistry (IHC) of anti-HSPH1 antibody

Formalin-fixed and paraffin-embedded human testis tissue reacted with HSPH1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-HSPH1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS645124

Flow Cytometry (FC/FACS) of anti-HSPH1 antibody

HSPH1 Antibody (Center) flow cytometric analysis of k562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-HSPH1 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS645124

Other Notes

Small volumes of anti-HSPH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HSPH1 purchase

MBS645124 is an antibody targeting HSPH1. Also known as HSPH1, ID (HSPH1, HSP105, HSP110, KIAA0201, Heat shock protein 105kD, Antigen NY-CO-25, Heat shock 110kD protein). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HSPH1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
heat shock protein 105 kDa
NCBI Official Synonym Full Names
heat shock 105kDa/110kDa protein 1<
NCBI Official Symbol
HSPH1
UniProt Protein Name
Heat shock protein 105 kDa
UniProt Synonym Protein Names
Heat shock 110 kDa protein
Protein Family
UniProt Gene Name
HSPH1
UniProt Entry Name
HS105_BOVIN
NCBI Protein Information
heat shock protein 105 kDa; heat shock 110 kDa protein

UniProt Comments for HSPH1

Function: Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities

By similarity.

Subunit structure: Interacts with HSPA8/HSC70

By similarity.

Subcellular location: Cytoplasm

By similarity.

Post-translational modification: Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity

By similarity.

Sequence similarities: Belongs to the heat shock protein 70 family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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