Rabbit Anti-TRAPPC9 Polyclonal Antibody – Cat# MBS645127

TRAPPC9 Antibody – Rabbit Polyclonal

Name: TRAPPC9 Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS645127
Price: 710 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645127

NIBP is a 1246aa intracellular regulatory protein. Reports suggest that NIBP physically interacts with NIK, IKK (beta), but not IKK (alpha) or IKK (gamma) and thus acts as a novel enhancer of cytokine-induced NF-(kappa) B signaling pathway. Due to its… More details

$710 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NIBP (TRAPPC9), Polyclonal Antibody

Full Product Name

NIBP (Trafficking Protein Particle Complex Subunit 9, NIK- and IKBKB-binding Protein, Tularik Gene 1 Protein, TRAPPC9, KIAA1882, T1)

Product Gene Name

anti-TRAPPC9 antibody

Product Synonym Names

Anti -NIBP (Trafficking Protein Particle Complex Subunit 9, NIK- and IKBKB-binding Protein, Tularik Gene 1 Protein, TRAPPC9, KIAA1882, T1)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Bovine, Canine, Chicken, Human, Monkey, Mouse

Form/Format

Supplied as a liquid, 0.025% sodium azide, 50% glycerol.

Purity/Purification

Serum
Serum

Specificity

Recognizes human NIBP. Species Crossreactivity

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

128,530 Da

Chromosome Location

Chromosome: 8; NC_000008.10 (140740324..141468678, complement). Location: 8q24.3

OMIM

611966

3D Structure

ModBase 3D Structure for Q96Q05

Immunogen

Synthetic peptide corresponding to aa282-299 (KKDFVGLDTDSRHYKKRC) of human NIBP.

Product Categories/Family for anti-TRAPPC9 antibody

Antibodies; Abs to Signal Transduction

Applications Tested/Suitable for anti-TRAPPC9 antibody

Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)

Application Notes for anti-TRAPPC9 antibody

Suitable for use in Immunofluorescence, Western Blot, Immunocytochemistry and Immunoprecipitation.

Other Notes

Small volumes of anti-TRAPPC9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRAPPC9 purchase

MBS645127 is an antibody targeting TRAPPC9. Also known as NIBP (Trafficking Protein Particle Complex Subunit 9, NIK- and IKBKB-binding Protein, Tularik Gene 1 Protein, TRAPPC9, KIAA1882, T1). Reactive in Bovine, Canine, Chicken, Human, Monkey, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TRAPPC9. It may not necessarily be applicable to this product.

NCBI GI #

34782807

NCBI GeneID

83696

NCBI Accession #

AAH06206.3

UniProt Primary Accession #

Q96Q05

UniProt Secondary Accession #

Q4VTT3; Q658K7; Q6P149; Q6ZQT3; Q7L5C4; Q86Y21; Q96SL2; Q9BQA2

UniProt Related Accession #

Q96Q05

NCBI Official Full Name

NIBP protein

NCBI Official Synonym Full Names

trafficking protein particle complex 9

NCBI Official Symbol

TRAPPC9

NCBI Official Synonym Symbols

T1; IBP; NIBP; MRT13; TRS120; IKBKBBP

UniProt Protein Name

Trafficking protein particle complex subunit 9

UniProt Synonym Protein Names

NIK- and IKBKB-binding protein; Tularik gene 1 protein

Protein Family

Trafficking protein particle complex

UniProt Gene Name

TRAPPC9

UniProt Synonym Gene Names

KIAA1882; NIBP

UniProt Entry Name

TPPC9_HUMAN

NCBI Protein Information

trafficking protein particle complex subunit 9; IKK2 binding protein; TRAPP 120 kDa subunit; tularik gene 1 protein; NIK- and IKBKB-binding protein; NIK and IKK-beta binding protein

NCBI Summary for TRAPPC9

This gene encodes a protein that likely plays a role in NF-kappa-B signaling. Mutations in this gene have been associated with autosomal-recessive mental retardation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]

UniProt Comments for TRAPPC9

NIBP: Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to Golgi. Defects in TRAPPC9 are the cause of mental retardation autosomal recessive type 13 (MRT13). Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Brain magnetic resonance imaging of MRT13 patients indicates the presence of mild cerebral white matter hypoplasia. Microcephaly is present in some but not all affected individuals. Belongs to the NIBP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Activator

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: Golgi apparatus; endoplasmic reticulum

Biological Process: cell differentiation

Disease: Mental Retardation, Autosomal Recessive 13

Research Articles on TRAPPC9

1. By detailed phenotypic analysis of our patients, and by critical literature review, we found that homozygous TRAPPC9 loss-of-function mutations cause a distinctive phenotype, characterized by peculiar facial appearance, obesity, hypotonia

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-TRAPPC9 antibody

Disease Name	Pubmed Publications
Neurobehavioral Manifestations Antibodies	>8 publications with TRAPPC9 and Neurobehavioral Manifestations
Congenital Abnormalities Antibodies	>3 publications with TRAPPC9 and Congenital Abnormalities
Necrosis Antibodies	>2 publications with TRAPPC9 and Necrosis
Immune System Diseases Antibodies	>1 publications with TRAPPC9 and Immune System Diseases
Breast Neoplasms Antibodies	>1 publications with TRAPPC9 and Breast Neoplasms
Neoplasms Antibodies	>1 publications with TRAPPC9 and Neoplasms

Organs/Tissues associated with anti-TRAPPC9 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>7 publications with TRAPPC9 and Brain