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IL22RA1 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645209

The interleukin-22 receptor A1 (IL-22 Ra1), also known as CRF2-9, is a 557aa, ~65kD type I transmembrane protein of the type II cytokine receptor family (CRF). IL-22 RA1 forms an IL-22 signaling complex with IL-10 RB/CRF2-4 on epithelial and stromal cells.… More details

$880 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL22RA1, Polyclonal Antibody
Full Product Name
IL22RA1 (Interleukin-22 Receptor Subunit alpha-1, IL-22 Receptor Subunit alpha-1, IL-22R-alpha-1, IL-22RA1, Cytokine Receptor Class-II Member 9, Cytokine Receptor Family 2 Member 9, CRF2-9, ZcytoR11, IL22R)
Product Gene Name
Product Synonym Names
Anti -IL22RA1 (Interleukin-22 Receptor Subunit alpha-1, IL-22 Receptor Subunit alpha-1, IL-22R-alpha-1, IL-22RA1, Cytokine Receptor Class-II Member 9, Cytokine Receptor Family 2 Member 9, CRF2-9, ZcytoR11, IL22R)
Immunogen Sequence
MRTLLTILTV GSLAAHAPED PSDLLQHVKF QSSNFENILT WDSGPEGTPD TVYSIEYKTY GERDWVAKKG CQRITRKSCN LTVETGNLTE LYYARVTAVS AGGRSATKMT DRFSSLQHTT LKPPDVTCIS KVRSIQMIVH PTPTPIRAGD GHRLTLEDIF HDLFYHLELQ VNRTYQMHLG GKQREYEFFG LTPDTEFLGT IMICVPTWAK ESAPYMCRVK TLPDRTWTYS FSGAFLFSMG FLVAVLCYLS YRYVTKPPAP PNSLNVQRVL TFQPLRFIQE HVLIPVFDLS GPSSLAQPVQ YSQIRVSGPR EPAGAPQRHS LSEITYLGQP DISILQPSNV PPPQILSPLS YAPNAAPEVG PPSYAPQVTP EAQFPFYAPQ AISKVQPSSY APQATPDSWP PSYGVCMEGS GKDSPTGTLS SPKHLRPKGQ LQKEPPAGSC MLGGLSLQEV TSLAMEESQE AKSLHQPLGI CTDRTSDPNV LHSGEEGTPQ YLKGQLPLLS SVQIEGHPMS LPLQPPSRPC SPSDQGPSPW GLLESLVCPK DEAKSPAPET SDLEQPTELD SLFRGLALTV QWES
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human IL22RA1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
63,776 Da
Chromosome Location
Chromosome: 2; AC_000159.1 (129351698..129378160). Location: chromosome: 2
3D Structure
ModBase 3D Structure for Q3SYS8
Immunogen
Full length human IL22RA1, aa1-574 (NP_067081.2).
Applications Tested/Suitable for anti-IL22RA1 antibody
Western Blot (WB)
Application Notes for anti-IL22RA1 antibody
Suitable for use in Western Blot.

Flow Cytometry (FC/FACS) of anti-IL22RA1 antibody

FACS analysis of negative control 293 cells (Black) and IL22RA1 expressing 293 cells (Green) using IL22RA1 purified mouse polyclonal antibody.
Mouse Anti-IL22RA1 Polyclonal Antibody – Cat# MBS645209

Western Blot (WB) of anti-IL22RA1 antibody

Western Blot analysis of IL22RA1 expression in transfected 293T cell line by IL22RA1 polyclonal antibody. Lane 1: IL22RA1 transfected lysate (63.14kD). Lane 2: Non-transfected lysate.
Mouse Anti-IL22RA1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS645209

Other Notes

Small volumes of anti-IL22RA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL22RA1 purchase

MBS645209 is an antibody targeting IL22RA1. Also known as IL22RA1 (Interleukin-22 Receptor Subunit alpha-1, IL-22 Receptor Subunit alpha-1, IL-22R-alpha-1, IL-22RA1, Cytokine Receptor Class-II Member 9, Cytokine Receptor Family 2 Member 9, CRF2-9, ZcytoR11, IL22R). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for IL22RA1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-22 receptor subunit alpha-1
NCBI Official Synonym Full Names
interleukin 22 receptor, alpha 1<
NCBI Official Symbol
IL22RA1
UniProt Protein Name
Interleukin-22 receptor subunit alpha-1
UniProt Gene Name
IL22RA1
UniProt Synonym Gene Names
IL-22 receptor subunit alpha-1; IL-22R-alpha-1; IL-22RA1
UniProt Entry Name
I22R1_BOVIN
NCBI Protein Information
interleukin-22 receptor subunit alpha-1; IL-22RA1; IL-22R-alpha-1; IL-22 receptor subunit alpha-1

UniProt Comments for IL22RA1

Function: Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation

By similarity.

Subunit structure: Heterodimer with IL10RB and with IL20RB

By similarity.

Subcellular location: Membrane; Single-pass type I membrane protein.

Sequence similarities: Belongs to the type II cytokine receptor family.Contains 2 fibronectin type-III domains.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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