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Cortistatin-29 (CORT) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645245

MBS645245 is an antibody targeting CORT. Also known as Cortistatin-29 (Cortistatin, CORT, UNQ307/PRO350). Reactive in Rat. Host: Rabbit. More details

$1195 / 0.4 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cortistatin-29, Polyclonal Antibody
Full Product Name
Cortistatin-29 (Cortistatin, CORT, UNQ307/PRO350)
Product Gene Name
Product Synonym Names
Anti -Cortistatin-29 (Cortistatin, CORT, UNQ307/PRO350)
Immunogen Sequence
pGlu-Glu-A rg-Pro-Pro -Leu-Gln-G ln-Pro-Pro -His-Arg-A sp-Lys-Lys -Pro-Cys-L ys-Asn-Phe -Phe-Trp-L ys-Thr-Phe -Ser-Ser-C ys-Lys
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Rat
Form/Format
Supplied as a lyophilized powder. Reconstitute with sterile dH2O.
Purity/Purification
Purified
Purified
Specificity
Recognizes rat Cortistatin-29.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
11,532 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (10509776..10512060). Location: 1p36.22
OMIM
602784
3D Structure
ModBase 3D Structure for O00230
Immunogen
Synthetic peptide corresponding to rat Cortistatin-29.

Product Categories/Family for anti-CORT antibody

Applications Tested/Suitable for anti-CORT antibody
ELISA (EL/EIA)
Application Notes for anti-CORT antibody
Suitable for use in ELISA.

Other Notes

Small volumes of anti-CORT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CORT. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cortistatin preproprotein
NCBI Official Synonym Full Names
cortistatin
NCBI Official Symbol
CORT
NCBI Official Synonym Symbols
CST-14; CST-17; CST-29
UniProt Protein Name
Cortistatin
Protein Family
UniProt Gene Name
CORT
UniProt Entry Name
CORT_HUMAN
NCBI Protein Information
cortistatin; cortistatin-14; cortistatin-17; cortistatin-29; preprocortistatin; prepro-cortistatin

NCBI Summary for CORT

This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739. [provided by RefSeq, Nov 2010]
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UniProt Comments for CORT

CORT: Binds to all human somatostatin receptor (SSTR) subtypes. It also inhibits cAMP production induced by forskolin through SSTRs. Belongs to the somatostatin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1p36.22

Cellular Component: extracellular space

Molecular Function: neuropeptide hormone activity; G-protein-coupled receptor binding

Biological Process: synaptic transmission; G-protein signaling, adenylate cyclase inhibiting pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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