Rabbit Anti-STK24 Polyclonal Antibody – Cat# MBS645254

Mouse Stk24 Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the Stk24 antibody detected the Stk24 protein (arrow).

STK24 Antibody – Rabbit Polyclonal

Name: STK24 Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS645254
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645254

MBS645254 is an antibody targeting STK24. Also known as Stk24, ID (Stk24, Mst3, Stk3, Serine/threonine-protein kinase 24, Mammalian STE20-like protein kinase 3, STE20-like kinase MST3, Serine/threonine-protein kinase 24 35kD subunit, Mammalian STE20-like… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Stk24, Polyclonal Antibody

Full Product Name

Stk24, ID (Stk24, Mst3, Stk3, Serine/threonine-protein kinase 24, Mammalian STE20-like protein kinase 3, STE20-like kinase MST3, Serine/threonine-protein kinase 24 35kD subunit, Mammalian STE20-like protein kinase 3 N-terminal, Serine/threonine-protein ki

Product Gene Name

anti-STK24 antibody

Product Synonym Names

Anti -Stk24, ID (Stk24, Mst3, Stk3, Serine/threonine-protein kinase 24, Mammalian STE20-like protein kinase 3, STE20-like kinase MST3, Serine/threonine-protein kinase 24 35kD subunit, Mammalian STE20-like protein kinase 3 N-terminal, Serine/threonine-protein ki

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human, mouse

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

49,308 Da

Chromosome Location

Chromosome: 13; NC_000013.10 (99102455..99229396, complement). Location: 13q31.2-q32.3

OMIM

604984

3D Structure

ModBase 3D Structure for Q9Y6E0

Immunogen

Mouse Stk24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-249 amino acids from the Central region of mouse Stk24.

Product Categories/Family for anti-STK24 antibody

Antibodies; Abs to Protein Kinases

Applications Tested/Suitable for anti-STK24 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-STK24 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-STK24 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for STK24. It may not necessarily be applicable to this product.

NCBI GI #

110349738

NCBI GeneID

8428

NCBI Accession #

NP_001027467.2

UniProt Primary Accession #

Q9Y6E0

UniProt Secondary Accession #

O14840; Q5JV92

UniProt Related Accession #

Q9Y6E0

GenBank Nucleotide #

NM_001032296.2

NCBI Official Full Name

serine/threonine-protein kinase 24 isoform b

NCBI Official Synonym Full Names

serine/threonine kinase 24

NCBI Official Symbol

STK24

NCBI Official Synonym Symbols

MST3; STK3; MST3B; STE20

UniProt Protein Name

Serine/threonine-protein kinase 24

UniProt Synonym Protein Names

Mammalian STE20-like protein kinase 3; MST-3; STE20-like kinase MST3Cleaved into the following 2 chains:Serine/threonine-protein kinase 24 36 kDa subunit; Alternative name(s):; Mammalian STE20-like protein kinase 3 N-terminal; MST3/NSerine/threonine-protein kinase 24 12 kDa subunit; Alternative name(s):; Mammalian STE20-like protein kinase 3 C-terminal

Protein Family

Serine/threonine-protein kinase

UniProt Gene Name

STK24

UniProt Synonym Gene Names

MST3; STK3; MST-3; MST3/N; MST3/C

UniProt Entry Name

STK24_HUMAN

NCBI Protein Information

serine/threonine-protein kinase 24; STE20-like kinase 3; STE20-like kinase MST3; sterile 20-like kinase 3; mammalian STE20-like protein kinase 3; serine/threonine kinase 24 (STE20 homolog, yeast)

NCBI Summary for STK24

The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000 [PubMed 10644707]).[supplied by OMIM, Mar 2008]

UniProt Comments for STK24

MST3: a protein kinase of the STE20 family. Activated by caspase-mediated cleavage

Protein type: Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.1; STE group; STE20 family; YSK subfamily

Chromosomal Location of Human Ortholog: 13q31.2-q32.3

Cellular Component: nucleoplasm; membrane; cytoplasm; nucleolus; cytosol; nucleus

Molecular Function: protein serine/threonine kinase activity; protein binding; metal ion binding; ATP binding; protein kinase activity; receptor signaling protein serine/threonine kinase activity

Biological Process: regulation of axon regeneration; response to hydrogen peroxide; apoptosis; protein amino acid autophosphorylation; signal transduction; negative regulation of cell migration; induction of apoptosis by oxidative stress; protein amino acid phosphorylation; cell structure disassembly during apoptosis

Research Articles on STK24

1. These data provide molecular understanding of the mechanism by which MO25 isoforms regulates the activity of STE20 family protein kinases.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-STK24 antibody

Reference Product	PubMed Publications
PDCD10 antibody	>4 publications with STK24 and PDCD10
STRN antibody	>1 publications with STK24 and STRN

Pathways associated with anti-STK24 antibody

Products by Pathway	Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptotic Cleavage Of Cellular Proteins Pathway antibodies	Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
Apoptotic Execution Phase Pathway antibodies	Apoptotic Execution Phase Pathway Diagram

Diseases associated with anti-STK24 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>5 publications with STK24 and Neoplasms
Nervous System Diseases Antibodies	>4 publications with STK24 and Nervous System Diseases
Congenital Abnormalities Antibodies	>2 publications with STK24 and Congenital Abnormalities
Cardiovascular Diseases Antibodies	>2 publications with STK24 and Cardiovascular Diseases
Disease Models, Animal Antibodies	>1 publications with STK24 and Disease Models, Animal
Brain Diseases Antibodies	>1 publications with STK24 and Brain Diseases
Inflammation Antibodies	>1 publications with STK24 and Inflammation

Organs/Tissues associated with anti-STK24 antibody

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>4 publications with STK24 and Nerve
Vascular Antibodies	>2 publications with STK24 and Vascular
Eye Antibodies	>2 publications with STK24 and Eye
Placenta Antibodies	>2 publications with STK24 and Placenta
Ganglia Antibodies	>1 publications with STK24 and Ganglia
Brain Antibodies	>1 publications with STK24 and Brain