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ZNF274 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645256

This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes… More details

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Product Overview

Online Datasheet in PDF
Product Name
ZNF274, Polyclonal Antibody
Full Product Name
ZNF274, NT (ZNF274, ZKSCAN19, Neurotrophin receptor-interacting factor homolog, Zinc finger protein 274, Zinc finger protein HFB101, Zinc finger protein with KRAB and SCAN domains 19, Zinc finger protein zfp2)
Product Gene Name
Product Synonym Names
Anti -ZNF274, NT (ZNF274, ZKSCAN19, Neurotrophin receptor-interacting factor homolog, Zinc finger protein 274, Zinc finger protein HFB101, Zinc finger protein with KRAB and SCAN domains 19, Zinc finger protein zfp2)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
69,254 Da
Chromosome Location
Chromosome: 18; AC_000175.1 (65731933..65758296). Location: chromosome: 18
3D Structure
ModBase 3D Structure for A6QPT6
Immunogen
ZNF274 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-82 amino acids from the N-terminal region of human ZNF274.
Applications Tested/Suitable for anti-ZNF274 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-ZNF274 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-ZNF274 antibody

ZNF274 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ZNF274 antibody detected the ZNF274 protein (arrow).
Rabbit Anti-ZNF274 Polyclonal Antibody – Cat# MBS645256

Other Notes

Small volumes of anti-ZNF274 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZNF274 purchase

MBS645256 is an antibody targeting ZNF274. Also known as ZNF274, NT (ZNF274, ZKSCAN19, Neurotrophin receptor-interacting factor homolog, Zinc finger protein 274, Zinc finger protein HFB101, Zinc finger protein with KRAB and SCAN domains 19, Zinc finger protein zfp2). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ZNF274. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ZNF274 protein
NCBI Official Synonym Full Names
zinc finger protein 274<
NCBI Official Symbol
ZNF274
UniProt Protein Name
Neurotrophin receptor-interacting factor homolog
UniProt Synonym Protein Names
Zinc finger protein 274
UniProt Gene Name
ZNF274
UniProt Entry Name
ZN274_BOVIN
NCBI Protein Information
neurotrophin receptor-interacting factor homolog

UniProt Comments for ZNF274

Function: Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression

By similarity.

Subunit structure: Interacts with SETDB1 and TRIM28/KAP1

By similarity.

Subcellular location: Cytoplasm

By similarity. Nucleus › nucleolus

By similarity.

Sequence similarities: Belongs to the krueppel C2H2-type zinc-finger protein family.Contains 5 C2H2-type zinc fingers.Contains 2 KRAB domains.Contains 1 SCAN box domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-ZNF274 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1 publications with ZNF274 and Liver
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