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TCHHL1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645284

S100A1 has been suggested to be a regulator of myocardial contractility. S100A1 improves cardiac contractile performance both by regulating sarcoplasmic reticulum calcium ion handling and myofibrillar calcium ion responsiveness. S100 is an astrocyte marker. More details

$940 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TCHHL1, Polyclonal Antibody
Full Product Name
TCHHL1, NT (S100A1, S-100, S100 calcium-binding protein A1)
Product Gene Name
Product Synonym Names
Anti -TCHHL1, NT (S100A1, S-100, S100 calcium-binding protein A1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in PBS, (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography
Specificity
Recognizes human S100A1/S100. Species Crossreactivity: Mouse, rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
99,275 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (152056620..152061540, complement). Location: 1q21.3
3D Structure
ModBase 3D Structure for Q5QJ38
Immunogen
Synthetic peptide corresponding to human S100A1/S100 at N-Terminal.
Applications Tested/Suitable for anti-TCHHL1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-TCHHL1 antibody
Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunohistochemistry.
Dilution: Immunofluorescence: 1:100-1:500
ELISA: 1:20,000
Western Blot: 1:500-1:1000
Immunohistochemistry (Paraffin): 10ug/ml

Immunohistochemistry (IHC) of anti-TCHHL1 antibody

Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-TCHHL1 Polyclonal Antibody – Cat# MBS645284

Western Blot (WB) of anti-TCHHL1 antibody

Western blot analysis of extracts from A549 cells, using S100 A1. The lane on the right is treated with the synthesized peptide.
Rabbit Anti-TCHHL1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS645284

Immunofluorescence (IF) of anti-TCHHL1 antibody

Immunofluorescence analysis of A549 cells, using S100 A1.The picture on the right is treated with the synthesized peptide.
Rabbit Anti-TCHHL1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS645284

Other Notes

Small volumes of anti-TCHHL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TCHHL1 purchase

MBS645284 is an antibody targeting TCHHL1. Also known as TCHHL1, NT (S100A1, S-100, S100 calcium-binding protein A1). Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TCHHL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
trichohyalin-like protein 1
NCBI Official Synonym Full Names
trichohyalin-like 1
NCBI Official Symbol
TCHHL1
NCBI Official Synonym Symbols
THHL1; S100A17
UniProt Protein Name
Trichohyalin-like protein 1
UniProt Synonym Protein Names
Basalin; Protein S100-A17; S100 calcium-binding protein A17
UniProt Gene Name
TCHHL1
UniProt Synonym Gene Names
S100A17; THHL1
UniProt Entry Name
TCHL1_HUMAN
NCBI Protein Information
trichohyalin-like protein 1; basalin; S100 calcium binding protein A17; S100 calcium-binding protein A17; intermediate filament-associated protein

NCBI Summary for TCHHL1

This gene belongs to the S100 fused-type protein (SFTP) gene family, and is located in a cluster of SFTP genes on chromosome 1q21. Several members of this family have been implicated in the development of complex skin disorders. This gene is evolutionarily conserved; its expression appears to be hair-specific and spatially restricted within the distal inner root sheath of the hair follicle. It thus may have an important role in hair morphogenesis. [provided by RefSeq, Aug 2013]
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UniProt Comments for TCHHL1

TCHHL1: Belongs to the S-100 family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 1q21.3

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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