Goat Anti-HMG20A Polyclonal Antibody – Cat# MBS645317

Human Spleen (formalin-fixed, paraffin-embedded) stained with HMG20A antibody at 2.5ug/ml followed by biotinylated goat IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.

HMG20A Antibody – Goat Polyclonal

Name: HMG20A Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS645317
Price: 785 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645317

Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the… More details

$785 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HMG20A, Polyclonal Antibody

Full Product Name

HMG20A, CT (High Mobility Group Protein 20A, HMG Box-containing Protein 20A, HMG Domain-containing Protein 1, HMG Domain-containing Protein HMGX1, HMGX1, HMGXB1)

Product Gene Name

anti-HMG20A antibody

Product Synonym Names

Anti -HMG20A, CT (High Mobility Group Protein 20A, HMG Box-containing Protein 20A, HMG Domain-containing Protein 1, HMG Domain-containing Protein HMGX1, HMGX1, HMGXB1)

Clonality

Polyclonal

Host

Goat

Species Reactivity

Human

Form/Format

Supplied as a liquid in TBS, pH 7.3, 0.5% BSA, 0.02% sodium azide.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes human HMG20A. Species sequence homology: mouse

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

40,144 Da

OMIM

605534

3D Structure

ModBase 3D Structure for Q9NP66

Immunogen

Synthetic peptide corresponding to C-ATVREVVNRLDR from the C-terminal of human HMG20A.

Product Categories/Family for anti-HMG20A antibody

Antibodies; Abs to Binding Proteins

Applications Tested/Suitable for anti-HMG20A antibody

ELISA (EL/EIA), Immunohistochemistry (IHC)

Application Notes for anti-HMG20A antibody

Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA: 1:32,000
Immunohistochemistry (Formalin fixed paraffin embedded): 2.5ug/ml

Other Notes

Small volumes of anti-HMG20A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HMG20A purchase

MBS645317 is an antibody targeting HMG20A. Also known as HMG20A, CT (High Mobility Group Protein 20A, HMG Box-containing Protein 20A, HMG Domain-containing Protein 1, HMG Domain-containing Protein HMGX1, HMGX1, HMGXB1). Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for HMG20A. It may not necessarily be applicable to this product.

NCBI GI #

7799124

NCBI Accession #

CAB90815.1

UniProt Primary Accession #

Q9NP66

UniProt Secondary Accession #

Q53G31; Q9NSF6; A6NHY3; D3DW78

NCBI Official Full Name

HMG20A

UniProt Protein Name

High mobility group protein 20A

UniProt Synonym Protein Names

HMG box-containing protein 20A; HMG domain-containing protein 1; HMG domain-containing protein HMGX1

Protein Family

High mobility group protein

UniProt Gene Name

HMG20A

UniProt Synonym Gene Names

HMGX1; HMGXB1

UniProt Entry Name

HM20A_HUMAN

UniProt Comments for HMG20A

HMG20A: Plays a role in neuronal differentiation as chromatin- associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 15q24

Cellular Component: nucleus

Molecular Function: protein binding; DNA binding; protein heterodimerization activity; chromatin binding; transcription factor activity

Biological Process: chromatin remodeling; negative regulation of neuron differentiation; establishment and/or maintenance of chromatin architecture; regulation of transcription, DNA-dependent; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-HMG20A antibody

Disease Name	Pubmed Publications
Diabetes Mellitus, Type 2 Antibodies	>5 publications with HMG20A and Diabetes Mellitus, Type 2
Muscular Diseases Antibodies	>1 publications with HMG20A and Muscular Diseases
Musculoskeletal Diseases Antibodies	>1 publications with HMG20A and Musculoskeletal Diseases

Organs/Tissues associated with anti-HMG20A antibody

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>1 publications with HMG20A and Nerve
Heart Antibodies	>1 publications with HMG20A and Heart
Muscle Antibodies	>1 publications with HMG20A and Muscle
Lung Antibodies	>1 publications with HMG20A and Lung
Embryonic Tissue Antibodies	>1 publications with HMG20A and Embryonic Tissue
Ovary Antibodies	>1 publications with HMG20A and Ovary
Pancreas Antibodies	>1 publications with HMG20A and Pancreas
Testis Antibodies	>1 publications with HMG20A and Testis
Brain Antibodies	>1 publications with HMG20A and Brain