Rabbit Anti-KANK2 Polyclonal Antibody – Cat# MBS645324

KANK2 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the KANK2 antibody detected the KANK2 protein (arrow).

KANK2 Antibody – Rabbit Polyclonal

Name: KANK2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS645324
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645324

ANKRD25 contains 5 ANK repeats. It is strongly expressed in cervix, colon, heart, kidney and lung. More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

KANK2, Polyclonal Antibody

Full Product Name

KANK2, ID (KANK2, ANKRD25, KIAA1518, MXRA3, SIP, KN motif and ankyrin repeat domain-containing protein 2, Ankyrin repeat domain-containing protein 25, Matrix-remodeling-associated protein 3, SRC-1-interacting protein)

Product Gene Name

anti-KANK2 antibody

Product Synonym Names

Anti -KANK2, ID (KANK2, ANKRD25, KIAA1518, MXRA3, SIP, KN motif and ankyrin repeat domain-containing protein 2, Ankyrin repeat domain-containing protein 25, Matrix-remodeling-associated protein 3, SRC-1-interacting protein)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

91,174 Da

Chromosome Location

Chromosome: 19; NC_000019.9 (11274943..11308243, complement). Location: 19p13.2

OMIM

614610

3D Structure

ModBase 3D Structure for Q63ZY3

Immunogen

KANK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 464-493 amino acids from the Central region of human KANK2.

Product Categories/Family for anti-KANK2 antibody

Antibodies; Abs to KIAA; orf

Applications Tested/Suitable for anti-KANK2 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-KANK2 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-KANK2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KANK2 purchase

MBS645324 is an antibody targeting KANK2. Also known as KANK2, ID (KANK2, ANKRD25, KIAA1518, MXRA3, SIP, KN motif and ankyrin repeat domain-containing protein 2, Ankyrin repeat domain-containing protein 25, Matrix-remodeling-associated protein 3, SRC-1-interacting protein). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KANK2. It may not necessarily be applicable to this product.

NCBI GI #

209969812

NCBI GeneID

25959

NCBI Accession #

NP_001129663.1

UniProt Primary Accession #

Q63ZY3

UniProt Secondary Accession #

Q3KQZ3; Q6GUF5; Q9H8S4; Q9NUP0; Q9P210; B0I1P4

UniProt Related Accession #

Q63ZY3

GenBank Nucleotide #

NM_001136191.2

NCBI Official Full Name

KN motif and ankyrin repeat domain-containing protein 2 isoform 2

NCBI Official Synonym Full Names

KN motif and ankyrin repeat domains 2

NCBI Official Symbol

KANK2

NCBI Official Synonym Symbols

SIP; MXRA3; ANKRD25

UniProt Protein Name

KN motif and ankyrin repeat domain-containing protein 2

UniProt Synonym Protein Names

Ankyrin repeat domain-containing protein 25; Matrix-remodeling-associated protein 3; SRC-1-interacting protein

Protein Family

KN motif and ankyrin repeat domain-containing protein

UniProt Gene Name

KANK2

UniProt Synonym Gene Names

ANKRD25; KIAA1518; MXRA3; SIP; SIP; SRC-interacting protein

UniProt Entry Name

KANK2_HUMAN

NCBI Protein Information

KN motif and ankyrin repeat domain-containing protein 2; SRC-interacting protein; SRC1-interacting protein; ankyrin repeat domain 25; SRC-1 interacting protein; SRC-1-interacting protein; matrix-remodelling associated 3; matrix-remodeling-associated protein 3; kidney ankyrin repeat-containing protein 2; ankyrin repeat domain-containing protein 25

UniProt Comments for KANK2

ANKRD25: a mammalian growth regulatory protein containing five Ankyrin repeats, common protein-protein interaction motifs. Ankyrin repeats are found in proteins with diverse functions including transcriptional initiators, cell-cycle regulators, cytoskeletal, and ion transporters. Three alternatively spliced isoforms have been described.

Protein type: Transcription regulation

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: mitochondrion; cytoplasm

Molecular Function: protein binding

Biological Process: negative regulation of cell proliferation; transcription, DNA-dependent; apoptosis; negative regulation of programmed cell death; negative regulation of transcription from RNA polymerase II promoter; negative regulation of estrogen receptor signaling pathway

Disease: Palmoplantar Keratoderma And Woolly Hair

Research Articles on KANK2

1. SIP, a novel ankyrin repeat containing protein, sequesters steroid receptor coactivators in the cytoplasm.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-KANK2 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>1 publications with KANK2 and Kidney