Mouse Anti-FCRL6 Monoclonal Antibody – Cat# MBS645585

Detection of FCRL6/FcRH6 in Human Peripheral Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Human FCRL6/FcRH6 Monoclonal Antibody followed by Allophycocyanin-conjugated Mouse IgG Secondary Antibody and Mouse Human NCAM-1/CD56 PE-conjugated Monoclonal Antibody. Quadrant markers were set based on control antibody staining.

FCRL6 Antibody – Mouse Monoclonal

Name: FCRL6 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS645585
Price: 1045 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645585

FCRL6 (Fc receptor-like protein 6; also FcRH6 and IFGP6) is a 66kD member of the Ig Superfamily. It is found on CD56dim CD16+ NK cells, CD56+ CD3+ NKT cells, gd T cells, and effector plus effector-memory CD8+ T cells. FCRL6 is not a receptor for… More details

$1045 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FcRL6, Monoclonal Antibody

Full Product Name

FcRL6 (Fc Receptor-like Protein 6, FcR-like Protein 6, Fc Receptor Homolog 6, IFGP6, FCRH6)

Product Gene Name

anti-FCRL6 antibody

Product Synonym Names

Anti -FcRL6 (Fc Receptor-like Protein 6, FcR-like Protein 6, Fc Receptor Homolog 6, IFGP6, FCRH6)

Clonality

Monoclonal

Isotype

IgG1

Clone Number

12K96

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a lyophilized powder in PBS, trehalose. Reconstitute with sterile PBS to 0.5mg/ml.

Purity/Purification

Affinity Purified
Purified by Protein A/G affinity chromatography.

Specificity

Recognizes human FCRL6. Does not react with recombinant human FCRL1, rhFCRL2, rhFCRL3, rhFCRL4, rhFCRL5, rhFcRN, or rhFCRLB/FCRY.

Preparation and Storage

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

47,748 Da

Chromosome Location

Chromosome: 1; NC_000001.10 (159770282..159786047). Location: 1q23.2

OMIM

613562

3D Structure

ModBase 3D Structure for Q6DN72

Immunogen

Recombinant corresponding to aa16-312 from human FCRL6 expressed in CHO cell line.

Product Categories/Family for anti-FCRL6 antibody

Antibodies; Abs to Receptors

Applications Tested/Suitable for anti-FCRL6 antibody

Flow Cytometry (FC/FACS)

Application Notes for anti-FCRL6 antibody

Suitable for use in Flow Cytometry.
Dilution: Flow Cytometry: 2.5ug labels 10e6 cells

Other Notes

Small volumes of anti-FCRL6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FCRL6 purchase

MBS645585 is an antibody targeting FCRL6. Also known as FcRL6 (Fc Receptor-like Protein 6, FcR-like Protein 6, Fc Receptor Homolog 6, IFGP6, FCRH6). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for FCRL6. It may not necessarily be applicable to this product.

NCBI GI #

545746369

NCBI GeneID

343413

NCBI Accession #

NP_001271146.1

UniProt Primary Accession #

Q6DN72

UniProt Secondary Accession #

Q6DN73; Q6XRC3; Q6ZNI1; A1KXW6; A2A4D6

UniProt Related Accession #

Q6DN72

GenBank Nucleotide #

NM_001284217.1

NCBI Official Full Name

Fc receptor-like protein 6 isoform 2

NCBI Official Synonym Full Names

Fc receptor-like 6

NCBI Official Symbol

FCRL6

NCBI Official Synonym Symbols

FcRH6

UniProt Protein Name

Fc receptor-like protein 6

UniProt Synonym Protein Names

Fc receptor homolog 6; FcRH6; IFGP6

Protein Family

Fc receptor-like protein

UniProt Gene Name

FCRL6

UniProt Synonym Gene Names

FCRH6; FcR-like protein 6; FcRL6; FcRH6

UniProt Entry Name

FCRL6_HUMAN

NCBI Protein Information

Fc receptor-like protein 6; IFGP6; fcR-like protein 6; leukocyte receptor; fc receptor homolog 6; Fc receptor-like protein 7; IgSF type I transmembrane receptor

UniProt Comments for FCRL6

Subunit structure: Interacts with PTPN11. Ref.1

Subcellular location: Membrane; Single-pass type I membrane protein

Potential.

Tissue specificity: Expressed by cytolytic cells including NK cells, effector and effector-memory CD8+ T-cells. Expression among T-cells is greatly expanded in HIV-1 infected individuals, and includes not only effector and effector-memory CD8+ T-cells but also populations of CD4+ T-cells. Ref.1

Domain: Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). The phosphorylated ITIM motif is involved in PTPN11 binding. Ref.1

Post-translational modification: Phosphorylated on Tyr residue, inducing association with PTPN11. Ref.1

Sequence similarities: Contains 3 Ig-like C2-type (immunoglobulin-like) domains.

Research Articles on FCRL6

1. Human FCRL6 receptor, selectively expressed by cytotoxic T and natural killer (NK) cells, directly binds the major histocompatibility complex (MHC) class II molecule HLA-DR.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-FCRL6 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>5 publications with FCRL6 and Blood
Spleen Antibodies	>1 publications with FCRL6 and Spleen