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SFTPD Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645588

Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. More details

$860 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SFTPD, Monoclonal Antibody
Full Product Name
SFTPD (Pulmonary Surfactant-associated Protein D, PSP-D, SP-D, Collectin-7, Lung Surfactant Protein D, COLEC7, PSPD, SFTP4)
Product Gene Name
anti-SFTPD antibody
Product Synonym Names
Anti -SFTPD (Pulmonary Surfactant-associated Protein D, PSP-D, SP-D, Collectin-7, Lung Surfactant Protein D, COLEC7, PSPD, SFTP4)
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
2A10
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human SFTPD.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
37,728 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (81697496..81708861, complement). Location: 10q22.2-q23.1
OMIM
178635
3D Structure
ModBase 3D Structure for P35247
Immunogen
Recombinant corresponding to aa21-376 from human SFTPD with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-SFTPD antibody

Antibodies; Abs to Pulmonary Proteins
Applications Tested/Suitable for anti-SFTPD antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SFTPD antibody
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml

Immunohistochemistry (IHC) of anti-SFTPD antibody

Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
Mouse Anti-SFTPD Monoclonal Antibody – Cat# MBS645588

Other Notes

Small volumes of anti-SFTPD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SFTPD purchase

MBS645588 is an antibody targeting SFTPD. Also known as SFTPD (Pulmonary Surfactant-associated Protein D, PSP-D, SP-D, Collectin-7, Lung Surfactant Protein D, COLEC7, PSPD, SFTP4). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for SFTPD. It may not necessarily be applicable to this product.

NCBI GI #
49456851
NCBI GeneID
6441
NCBI Accession #
CAG46746.1
UniProt Primary Accession #
P35247
UniProt Secondary Accession #
Q5T0M3; Q6FH08; Q86YK9; Q8TCD8; Q9UCJ2; Q9UCJ3
UniProt Related Accession #
P35247
NCBI Official Full Name
SFTPD
NCBI Official Synonym Full Names
surfactant protein D
NCBI Official Symbol
SFTPD
NCBI Official Synonym Symbols
SP-D; PSP-D; SFTP4; COLEC7
UniProt Protein Name
Pulmonary surfactant-associated protein D
UniProt Synonym Protein Names
Collectin-7; Lung surfactant protein D
Protein Family
Pulmonary surfactant-associated protein
UniProt Gene Name
SFTPD
UniProt Synonym Gene Names
COLEC7; PSPD; SFTP4; PSP-D; SP-D
UniProt Entry Name
SFTPD_HUMAN
NCBI Protein Information
pulmonary surfactant-associated protein D; collectin 7; collectin-7; lung surfactant protein D; pulmonary surfactant apoprotein; surfactant, pulmonary-associated protein D; surfactant-associated protein, pulmonary 4

NCBI Summary for SFTPD

The protein encoded by this gene is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The encoded protein may also be involved in surfactant metabolism. [provided by RefSeq, Jul 2015]

UniProt Comments for SFTPD

Function: Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

Subunit structure: Oligomeric complex of 4 set of homotrimers.

Subcellular location: Secreted › extracellular space › extracellular matrix. Secreted › extracellular space › surface film.

Post-translational modification: The N-terminus is blocked.Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates

By similarity.

Miscellaneous: Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C).

Sequence similarities: Belongs to the SFTPD family.Contains 1 C-type lectin domain.Contains 1 collagen-like domain.
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Research Articles on SFTPD

1. elevated expression in nasal mucosa in chronic rhinosinusitis with polyps

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SFTPD antibody

 Reference Product  PubMed Publications
 SFTPB antibody  >6 publications with SFTPD and SFTPB
 SFTPC antibody  >4 publications with SFTPD and SFTPC
 TLR4 antibody  >2 publications with SFTPD and TLR4

Pathways associated with anti-SFTPD antibody

 Products by Pathway  Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Regulation Of Retinoblastoma Protein Pathway antibodies  Regulation Of Retinoblastoma Protein Pathway Diagram

Diseases associated with anti-SFTPD antibody

 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >16 publications with SFTPD and Lung Diseases
 Inflammation Antibodies  >12 publications with SFTPD and Inflammation
 Lung Injury Antibodies  >7 publications with SFTPD and Lung Injury
 Pneumonia Antibodies  >4 publications with SFTPD and Pneumonia
 Acute Lung Injury Antibodies  >2 publications with SFTPD and Acute Lung Injury
 Respiratory Distress Syndrome, Adult Antibodies  >2 publications with SFTPD and Respiratory Distress Syndrome, Adult
 Neoplasms Antibodies  >2 publications with SFTPD and Neoplasms
 Necrosis Antibodies  >2 publications with SFTPD and Necrosis
 Asthma Antibodies  >2 publications with SFTPD and Asthma
 Premature Birth Antibodies  >2 publications with SFTPD and Premature Birth

Organs/Tissues associated with anti-SFTPD antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >28 publications with SFTPD and Lung
 Connective Tissue Antibodies  >1 publications with SFTPD and Connective Tissue
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