Rabbit Anti-RAB39B Polyclonal Antibody – Cat# MBS645647

RAB39B Antibody (N-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the RAB39B antibody detected the RAB39B protein (arrow).

RAB39B Antibody – Rabbit Polyclonal

Name: RAB39B Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS645647
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645647

This gene encodes a member of the Rab family of proteins. Rab proteins are small GTPases that are involved in vesicular trafficking. More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RAB39B, Polyclonal Antibody

Full Product Name

RAB39B, NT (RAB39B, Ras-related protein Rab-39B)

Product Gene Name

anti-RAB39B antibody

Product Synonym Names

Anti -RAB39B, NT (RAB39B, Ras-related protein Rab-39B)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human, mouse

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

24,622 Da

Chromosome Location

Chromosome: X; NC_000023.10 (154487526..154493852, complement). Location: Xq28

OMIM

300271

3D Structure

ModBase 3D Structure for Q96DA2

Immunogen

RAB39B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-40 amino acids from the N-terminal region of human RAB39B.

Product Categories/Family for anti-RAB39B antibody

Antibodies; Abs to GTPase; Rab; Ras; Rho Proteins

Applications Tested/Suitable for anti-RAB39B antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-RAB39B antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-RAB39B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB39B purchase

MBS645647 is an antibody targeting RAB39B. Also known as RAB39B, NT (RAB39B, Ras-related protein Rab-39B). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB39B. It may not necessarily be applicable to this product.

NCBI GI #

25188193

NCBI GeneID

116442

NCBI Accession #

NP_741995.1

UniProt Primary Accession #

Q96DA2

UniProt Secondary Accession #

Q5JT79; Q8NEX3

UniProt Related Accession #

Q96DA2

GenBank Nucleotide #

NM_171998.3

NCBI Official Full Name

ras-related protein Rab-39B

NCBI Official Synonym Full Names

RAB39B, member RAS oncogene family

NCBI Official Symbol

RAB39B

NCBI Official Synonym Symbols

MRX72

UniProt Protein Name

Ras-related protein Rab-39B

Protein Family

Ras-related protein

UniProt Gene Name

RAB39B

UniProt Entry Name

RB39B_HUMAN

NCBI Protein Information

ras-related protein Rab-39B

NCBI Summary for RAB39B

This gene encodes a member of the Rab family of proteins. Rab proteins are small GTPases that are involved in vesicular trafficking. Mutations in this gene are associated with X-linked mental retardation. [provided by RefSeq, Aug 2013]

UniProt Comments for RAB39B

Function: May be involved in vesicular trafficking. Plays a role in synapse formation

By similarity.

Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side

Potential. Golgi apparatus. Note: Partial colocalization with markers that cycle from the cell surface to the trans-Golgi network

By similarity. Ref.5

Tissue specificity: Highly expressed in the brain. Ref.5

Involvement in disease: Mental retardation, X-linked 72 (MRX72) [MIM:300271]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Intellectual deficiency is the only primary symptom of non-syndromic X-linked mental retardation, while syndromic mental retardation presents with associated physical, neurological and/or psychiatric manifestations. MRX72 patients can manifest autism spectrum disorder, seizures and macrocephaly as additional features.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.5

Sequence similarities: Belongs to the small GTPase superfamily. Rab family.

Research Articles on RAB39B

1. These results demonstrate developmental and functional neuronal alteration as a consequence of downregulation of RAB39B and emphasize the critical role of vesicular trafficking in the development of neurons and human intellectual abilities.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RAB39B antibody

Reference Product	PubMed Publications
CLIC2 antibody	>1 publications with RAB39B and CLIC2
VBP1 antibody	>1 publications with RAB39B and VBP1
TMLHE antibody	>1 publications with RAB39B and TMLHE
FUNDC2 antibody	>1 publications with RAB39B and FUNDC2

Diseases associated with anti-RAB39B antibody

Disease Name	Pubmed Publications
Gonadal Disorders Antibodies	>1 publications with RAB39B and Gonadal Disorders
Congenital Abnormalities Antibodies	>1 publications with RAB39B and Congenital Abnormalities
Mental Retardation, X-Linked Antibodies	>1 publications with RAB39B and Mental Retardation, X-Linked
Intellectual Disability Antibodies	>1 publications with RAB39B and Intellectual Disability
Epilepsy Antibodies	>1 publications with RAB39B and Epilepsy
Autistic Disorder Antibodies	>1 publications with RAB39B and Autistic Disorder
Craniofacial Abnormalities Antibodies	>1 publications with RAB39B and Craniofacial Abnormalities

Organs/Tissues associated with anti-RAB39B antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>2 publications with RAB39B and Brain
Eye Antibodies	>1 publications with RAB39B and Eye