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CRHBP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645698

Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CRHBP, Polyclonal Antibody
Full Product Name
CRHBP, NT (CRHBP, CRFBP, Corticotropin-releasing factor-binding protein, Corticotropin-releasing hormone-binding protein)
Product Gene Name
Product Synonym Names
Anti -CRHBP, NT (CRHBP, CRFBP, Corticotropin-releasing factor-binding protein, Corticotropin-releasing hormone-binding protein)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Purified
Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
36,144 Da
Chromosome Location
Chromosome: 5; NC_000005.9 (76248680..76265299). Location: 5q11.2-q13.3
OMIM
122559
3D Structure
ModBase 3D Structure for P24387
Immunogen
CRHBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-36 amino acids from the N-terminal region of human CRHBP.
Applications Tested/Suitable for anti-CRHBP antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-CRHBP antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:50-100

Western Blot (WB) of anti-CRHBP antibody

Western blot analysis of CRHBP (arrow) using rabbit polyclonal CRHBP Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CRHBP gene.
Rabbit Anti-CRHBP Polyclonal Antibody – Cat# MBS645698

Other Notes

Small volumes of anti-CRHBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CRHBP purchase

MBS645698 is an antibody targeting CRHBP. Also known as CRHBP, NT (CRHBP, CRFBP, Corticotropin-releasing factor-binding protein, Corticotropin-releasing hormone-binding protein). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CRHBP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
corticotropin-releasing factor-binding protein
NCBI Official Synonym Full Names
corticotropin releasing hormone binding protein
NCBI Official Symbol
CRHBP
NCBI Official Synonym Symbols
CRFBP; CRF-BP
UniProt Protein Name
Corticotropin-releasing factor-binding protein
UniProt Synonym Protein Names
Corticotropin-releasing hormone-binding protein
UniProt Gene Name
CRHBP
UniProt Synonym Gene Names
CRFBP; CRF-BP; CRF-binding protein; CRH-BP
UniProt Entry Name
CRHBP_HUMAN
NCBI Protein Information
corticotropin-releasing factor-binding protein; CRH-BP; CRF-binding protein; corticotropin releasing hormone-binding protein; corticotropin-releasing hormone-binding protein

UniProt Comments for CRHBP

Function: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.

Subcellular location: Secreted.

Sequence similarities: Belongs to the CRF-binding protein family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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