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PCGF5 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645719

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and… More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PCGF5, Monoclonal Antibody
Full Product Name
PCGF5 (Polycomb Group RING Finger Protein 5, RING Finger Protein 159, RNF159, MGC16202)
Product Gene Name
Product Synonym Names
Anti -PCGF5 (Polycomb Group RING Finger Protein 5, RING Finger Protein 159, RNF159, MGC16202)
Immunogen Sequence
NDCPRCGNQV HETNPLEMLR LDNTLEEIIF KLVPGLREQE LERESEFWKK NKPQENGQDD TSKADKPKVD EEGDENEDDK DYHRSDPQIA ICLDCLRN
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
3C10
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human PCGF5.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
29,714 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (92922769..93044088). Location: 10q23.32
3D Structure
ModBase 3D Structure for Q86SE9
Immunogen
Partial recombinant corresponding to aa51-149 from human PCGF5 (NP_115749) with GST tag. MW of the GST tag alone is 26kD.
Applications Tested/Suitable for anti-PCGF5 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-PCGF5 antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-PCGF5 antibody

Western Blot detection against Immunogen (36.89kD).
Mouse Anti-PCGF5 Monoclonal Antibody – Cat# MBS645719

Western Blot (WB) of anti-PCGF5 antibody

Western Blot analysis of PCGF5 expression in transfected 293T cell line by PCGF5 monoclonal antibody. Lane 1: PCGF5 transfected lysate (29.7kD).|Lane 2: Non-transfected lysate.
Mouse Anti-PCGF5 Monoclonal Antibody, Western Blot (WB) – Cat# MBS645719

Other Notes

Small volumes of anti-PCGF5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PCGF5 purchase

MBS645719 is an antibody targeting PCGF5. Also known as PCGF5 (Polycomb Group RING Finger Protein 5, RING Finger Protein 159, RNF159, MGC16202). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PCGF5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
PCGF5 protein
NCBI Official Synonym Full Names
polycomb group ring finger 5
NCBI Official Symbol
PCGF5
NCBI Official Synonym Symbols
RNF159
UniProt Protein Name
Polycomb group RING finger protein 5
UniProt Synonym Protein Names
RING finger protein 159
UniProt Gene Name
PCGF5
UniProt Synonym Gene Names
RNF159
UniProt Entry Name
PCGF5_HUMAN
NCBI Protein Information
polycomb group RING finger protein 5; RING finger protein 159; ring finger protein (C3HC4 type) 159

UniProt Comments for PCGF5

Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Subunit structure: Component of a PRC1-like complex. Interacts with CBX6, CBX7 and CBX8. Ref.5

Subcellular location: Nucleus Ref.5.

Sequence similarities: Contains 1 RING-type zinc finger.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PCGF5 antibody

 Reference Product  PubMed Publications
 PCGF1 antibody  >1 publications with PCGF5 and PCGF1

Organs/Tissues associated with anti-PCGF5 antibody

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