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PLSCR4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645782

PLSCR4 may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot… More details

$895 / 0.2 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PLSCR4, Polyclonal Antibody
Full Product Name
PLSCR4, ID (PLSCR4, Phospholipid scramblase 4, Ca(2+)-dependent phospholipid scramblase 4, Cell growth-inhibiting gene 43 protein, TRA1)
Product Gene Name
anti-PLSCR4 antibody
Product Synonym Names
Anti -PLSCR4, ID (PLSCR4, Phospholipid scramblase 4, Ca(2+)-dependent phospholipid scramblase 4, Cell growth-inhibiting gene 43 protein, TRA1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human, mouse (predicted)
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
37,005 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (145910122..145968966, complement). Location: 3q24
OMIM
607612
3D Structure
ModBase 3D Structure for Q9NRQ2
Immunogen
PLSCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-151 amino acids from the Central region of human PLSCR4.

Product Categories/Family for anti-PLSCR4 antibody

Antibodies; Abs to Enzymes
Applications Tested/Suitable for anti-PLSCR4 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PLSCR4 antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Western Blot (WB) of anti-PLSCR4 antibody

PLSCR4 Antibody (Center) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the PLSCR4 antibody detected the PLSCR4 protein (arrow).
Rabbit Anti-PLSCR4 Polyclonal Antibody – Cat# MBS645782

Immunohistochemistry (IHC) of anti-PLSCR4 antibody

PLSCR4 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PLSCR4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-PLSCR4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS645782

Other Notes

Small volumes of anti-PLSCR4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLSCR4 purchase

MBS645782 is an antibody targeting PLSCR4. Also known as PLSCR4, ID (PLSCR4, Phospholipid scramblase 4, Ca(2+)-dependent phospholipid scramblase 4, Cell growth-inhibiting gene 43 protein, TRA1). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PLSCR4. It may not necessarily be applicable to this product.

NCBI GI #
190341019
NCBI GeneID
57088
NCBI Accession #
NP_001121777.1
UniProt Primary Accession #
Q9NRQ2
UniProt Secondary Accession #
Q2TTR3; Q658L3; Q6ZR73; Q7Z505; A8K2E9
UniProt Related Accession #
Q9NRQ2
GenBank Nucleotide #
NM_001128305.1
NCBI Official Full Name
phospholipid scramblase 4 isoform a
NCBI Official Synonym Full Names
phospholipid scramblase 4
NCBI Official Symbol
PLSCR4
NCBI Official Synonym Symbols
TRA1
UniProt Protein Name
Phospholipid scramblase 4
UniProt Synonym Protein Names
Ca(2+)-dependent phospholipid scramblase 4; Cell growth-inhibiting gene 43 protein; TRA1
Protein Family
Phospholipid scramblase
UniProt Gene Name
PLSCR4
UniProt Synonym Gene Names
PL scramblase 4
UniProt Entry Name
PLS4_HUMAN
NCBI Protein Information
phospholipid scramblase 4; PL scramblase 4; cell growth inhibiting protein 43; Ca(2+)-dependent phospholipid scramblase 4

UniProt Comments for PLSCR4

Function: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.

Cofactor: Calcium or magnesium. Ref.10

Subunit structure: Interacts with PDCD6. Ref.9

Subcellular location: Membrane; Single-pass type II membrane protein

By similarity.

Tissue specificity: Expressed in heart, brain, placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, uterus, small intestine and colon. Not detected in peripheral blood lymphocytes.

Sequence similarities: Belongs to the phospholipid scramblase family.

Sequence caution: The sequence AAP97186.1 differs from that shown. Reason: Frameshift at positions 152, 155, 163 and 325.
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Research Articles on PLSCR4

1. biochemical and functional characterization of human phospholipid scramblase 4

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PLSCR4 antibody

 Reference Product  PubMed Publications
 PLSCR1 antibody  >4 publications with PLSCR4 and PLSCR1
 PDCD6 antibody  >1 publications with PLSCR4 and PDCD6

Diseases associated with anti-PLSCR4 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2 publications with PLSCR4 and Inflammation
 Weight Loss Antibodies  >1 publications with PLSCR4 and Weight Loss

Organs/Tissues associated with anti-PLSCR4 antibody

 Organ/Tissue Name  Pubmed Publications
 Uterus Antibodies  >2 publications with PLSCR4 and Uterus
 Spleen Antibodies  >1 publications with PLSCR4 and Spleen
 Bone Marrow Antibodies  >1 publications with PLSCR4 and Bone Marrow
 Adipose Tissue Antibodies  >1 publications with PLSCR4 and Adipose Tissue
 Muscle Antibodies  >1 publications with PLSCR4 and Muscle
 Connective Tissue Antibodies  >1 publications with PLSCR4 and Connective Tissue
 Brain Antibodies  >1 publications with PLSCR4 and Brain
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