Rabbit Anti-TUBB8 Polyclonal Antibody – Cat# MBS645792

TUBB8 Antibody (N-term) western blot analysis in 293,A549,HepG2,K562 cell line lysates (35ug/lane).This demonstrates the TUBB8 antibody detected the TUBB8 protein (arrow).

TUBB8 Antibody – Rabbit Polyclonal

Name: TUBB8 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS645792
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645792

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain (By similarity). More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TUBB8, Polyclonal Antibody

Full Product Name

TUBB8, NT (TUBB8, Tubulin beta-8 chain)

Product Gene Name

anti-TUBB8 antibody

Product Synonym Names

Anti -TUBB8, NT (TUBB8, Tubulin beta-8 chain)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

49,776 Da

Chromosome Location

Chromosome: 10; NC_000010.10 (92828..95178, complement). Location: 10p15.3

3D Structure

ModBase 3D Structure for Q3ZCM7

Immunogen

TUBB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human TUBB8.

Product Categories/Family for anti-TUBB8 antibody

Antibodies; Abs to Tubulin

Applications Tested/Suitable for anti-TUBB8 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-TUBB8 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-TUBB8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TUBB8 purchase

MBS645792 is an antibody targeting TUBB8. Also known as TUBB8, NT (TUBB8, Tubulin beta-8 chain). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TUBB8. It may not necessarily be applicable to this product.

NCBI GI #

42558279

NCBI GeneID

347688

NCBI Accession #

NP_817124.1

UniProt Primary Accession #

Q3ZCM7

UniProt Secondary Accession #

Q5SQX9; Q8WZ78

UniProt Related Accession #

Q3ZCM7

GenBank Nucleotide #

NM_177987.2

NCBI Official Full Name

tubulin beta-8 chain isoform 1

NCBI Official Synonym Full Names

tubulin, beta 8 class VIII

NCBI Official Symbol

TUBB8

NCBI Official Synonym Symbols

bA631M21.2; RP11-631M21.2

UniProt Protein Name

Tubulin beta-8 chain

Protein Family

Tubulin

UniProt Gene Name

TUBB8

UniProt Entry Name

TBB8_HUMAN

NCBI Protein Information

tubulin beta-8 chain; class VIII beta-tubulin; HSA10p15 beta-tubulin 4Q

UniProt Comments for TUBB8

Function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain

By similarity.

Subunit structure: Dimer of alpha and beta chains

By similarity.

Subcellular location: Cytoplasm › cytoskeleton

By similarity.

Post-translational modification: Some glutamate residues at the C-terminus are polyglutamylated. This modification occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Also monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human. Monoglycylation is mainly limited to tubulin incorporated into axonemes (cilia and flagella) whereas glutamylation is prevalent in neuronal cells, centrioles, axonemes, and the mitotic spindle. Both modifications can coexist on the same protein on adjacent residues, and lowering glycylation levels increases polyglutamylation, and reciprocally. The precise function of such modifications is still unclear but they regulate the assembly and dynamics of axonemal microtubules

Probable.

Sequence similarities: Belongs to the tubulin family.

Sequence caution: The sequence CAI16221.1 differs from that shown. Reason: Erroneous gene model prediction.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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