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IL34 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645819

Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]). More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL34, Polyclonal Antibody
Full Product Name
IL34, NT (IL34, C16orf77, Interleukin-34)
Product Gene Name
Product Synonym Names
Anti -IL34, NT (IL34, C16orf77, Interleukin-34)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
26,294 Da
Chromosome Location
Chromosome: 18; AC_000175.1 (1548295..1608706, complement). Location: chromosome: 18
3D Structure
ModBase 3D Structure for A6QL48
Immunogen
IL34 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-53 amino acids from the N-terminal region of human IL34.

Product Categories/Family for anti-IL34 antibody

Applications Tested/Suitable for anti-IL34 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-IL34 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-IL34 antibody

IL34 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the IL34 antibody detected the IL34 protein (arrow).
Rabbit Anti-IL34 Polyclonal Antibody – Cat# MBS645819

Other Notes

Small volumes of anti-IL34 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL34 purchase

MBS645819 is an antibody targeting IL34. Also known as IL34, NT (IL34, C16orf77, Interleukin-34). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IL34. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
IL34 protein
NCBI Official Synonym Full Names
interleukin 34<
NCBI Official Symbol
IL34
NCBI Official Synonym Symbols
IL-34; C18H16ORF77
UniProt Protein Name
Interleukin-34
Protein Family
UniProt Gene Name
IL34
UniProt Synonym Gene Names
IL-34
UniProt Entry Name
IL34_BOVIN
NCBI Protein Information
interleukin-34

UniProt Comments for IL34

Function: Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1

By similarity.

Subunit structure: Homodimer. Interacts with CSF1R

By similarity.

Subcellular location: Secreted

By similarity.

Sequence similarities: Belongs to the IL-34 family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IL34 antibody

 Reference Product  PubMed Publications
 CSF1R antibody  >4 publications with IL34 and CSF1R

Organs/Tissues associated with anti-IL34 antibody

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