Rabbit Anti-PKD2L1 Polyclonal Antibody – Cat# MBS645824

PKD2L1 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PKD2L1 antibody detected the PKD2L1 protein (arrow).

PKD2L1 Antibody – Rabbit Polyclonal

Name: PKD2L1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS645824
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645824

PKD2L1 is a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PKD2L1, Polyclonal Antibody

Full Product Name

PKD2L1, NT (PKD2L1, PKD2L, PKDL, Polycystic kidney disease 2-like 1 protein, Polycystin-2 homolog, Polycystin-2L1, Polycystin-L, Polycystin-L1)

Product Gene Name

anti-PKD2L1 antibody

Product Synonym Names

Anti -PKD2L1, NT (PKD2L1, PKD2L, PKDL, Polycystic kidney disease 2-like 1 protein, Polycystin-2 homolog, Polycystin-2L1, Polycystin-L, Polycystin-L1)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

91,982 Da

Chromosome Location

Chromosome: 10; NC_000010.10 (102047903..102090243, complement). Location: 10q24

OMIM

604532

3D Structure

ModBase 3D Structure for Q9P0L9

Immunogen

PKD2L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human PKD2L1.

Product Categories/Family for anti-PKD2L1 antibody

Antibodies; Abs to Disease Markers

Applications Tested/Suitable for anti-PKD2L1 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-PKD2L1 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-PKD2L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PKD2L1 purchase

MBS645824 is an antibody targeting PKD2L1. Also known as PKD2L1, NT (PKD2L1, PKD2L, PKDL, Polycystic kidney disease 2-like 1 protein, Polycystin-2 homolog, Polycystin-2L1, Polycystin-L, Polycystin-L1). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PKD2L1. It may not necessarily be applicable to this product.

NCBI GI #

359465612

NCBI GeneID

9033

NCBI Accession #

NP_001240766.1

UniProt Primary Accession #

Q9P0L9

UniProt Secondary Accession #

O75972; Q5W039; Q9UP35; Q9UPA2

UniProt Related Accession #

Q9P0L9

GenBank Nucleotide #

NM_001253837.1

NCBI Official Full Name

polycystic kidney disease 2-like 1 protein isoform 2

NCBI Official Synonym Full Names

polycystic kidney disease 2-like 1

NCBI Official Symbol

PKD2L1

NCBI Official Synonym Symbols

PCL; PKDL; PKD2L; TRPP3

UniProt Protein Name

Polycystic kidney disease 2-like 1 protein

UniProt Synonym Protein Names

Polycystin-2 homolog; Polycystin-2L1; Polycystin-L; Polycystin-L1

Protein Family

Polycystic kidney disease 2-like 1 protein

UniProt Gene Name

PKD2L1

UniProt Synonym Gene Names

PKD2L; PKDL

UniProt Entry Name

PK2L1_HUMAN

NCBI Protein Information

polycystic kidney disease 2-like 1 protein; polycystin-L; polycystin-L1; polycystin-2L1; polycystin-2 homolog; transient receptor potential cation channel, subfamily P, member 3

NCBI Summary for PKD2L1

This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

UniProt Comments for PKD2L1

Function: May function as a subunit of an ion channel and act as a transducer of calcium-mediated signaling. Ref.8

Subcellular location: Membrane; Multi-pass membrane protein

Potential.

Tissue specificity: Expressed in adult heart, skeletal muscle, brain, spleen, testis, retina and liver. According to Ref.1, expressed at high levels in fetal tissues, including kidney and liver, and down-regulated in adult tissues. According to Ref.7, expressed in fetal brain, but not expressed in fetal lung, liver or kidney. Isoform 4 appears to be expressed only in transformed lymphoblasts. Ref.1 Ref.7

Sequence similarities: Belongs to the polycystin family.

Research Articles on PKD2L1

1. Trimerization may be important for both homo- and possibly heteromeric assemblies of PKD2L1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PKD2L1 antibody

Reference Product	PubMed Publications
PKD1L3 antibody	>20 publications with PKD2L1 and PKD1L3
TRPM5 antibody	>6 publications with PKD2L1 and TRPM5
GNB2L1 antibody	>1 publications with PKD2L1 and GNB2L1
RYR2 antibody	>1 publications with PKD2L1 and RYR2

Diseases associated with anti-PKD2L1 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>3 publications with PKD2L1 and Nervous System Diseases
Cardiovascular Diseases Antibodies	>1 publications with PKD2L1 and Cardiovascular Diseases

Organs/Tissues associated with anti-PKD2L1 antibody

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>8 publications with PKD2L1 and Testis
Brain Antibodies	>7 publications with PKD2L1 and Brain
Eye Antibodies	>4 publications with PKD2L1 and Eye
Lung Antibodies	>1 publications with PKD2L1 and Lung