Rabbit Anti-TAC4 Polyclonal Antibody – Cat# MBS645855

TAC4 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TAC4 antibody detected the TAC4 protein (arrow).

TAC4 Antibody – Rabbit Polyclonal

Name: TAC4 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS645855
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645855

This gene is a member of the tachykinin family of neurotransmitter-encoding genes. Tachykinin proteins are cleaved into small, secreted peptides that activate members of a family of receptor proteins. The products of this gene preferentially activate… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TAC4, Polyclonal Antibody

Full Product Name

TAC4, CT (TAC4, Tachykinin-4, Preprotachykinin-C, Endokinin-A, Endokinin-A/B, Endokinin-C)

Product Gene Name

anti-TAC4 antibody

Product Synonym Names

Anti -TAC4, CT (TAC4, Tachykinin-4, Preprotachykinin-C, Endokinin-A, Endokinin-A/B, Endokinin-C)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

12,305 Da

Chromosome Location

Chromosome: 17; NC_000017.10 (47915671..47925379, complement). Location: 17q21.33

OMIM

607833

3D Structure

ModBase 3D Structure for Q86UU9

Immunogen

TAC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-113 amino acids from the C-terminal region of human TAC4.

Product Categories/Family for anti-TAC4 antibody

Antibodies; Abs to Proteins

Applications Tested/Suitable for anti-TAC4 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-TAC4 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-TAC4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TAC4 purchase

MBS645855 is an antibody targeting TAC4. Also known as TAC4, CT (TAC4, Tachykinin-4, Preprotachykinin-C, Endokinin-A, Endokinin-A/B, Endokinin-C). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TAC4. It may not necessarily be applicable to this product.

NCBI GI #

133777256

NCBI GeneID

255061

NCBI Accession #

AAI00843.1

UniProt Primary Accession #

Q86UU9

UniProt Secondary Accession #

Q2M2P1; Q6ECK8; Q86UU6; Q86UU7; Q86UU8; Q8IWZ7

UniProt Related Accession #

Q86UU9

NCBI Official Full Name

TAC4 protein

NCBI Official Synonym Full Names

tachykinin 4 (hemokinin)

NCBI Official Symbol

TAC4

NCBI Official Synonym Symbols

EK; HK1; HK-1; PPT-C

UniProt Protein Name

Tachykinin-4

UniProt Synonym Protein Names

Preprotachykinin-C

Protein Family

Tachykinin

UniProt Gene Name

TAC4

UniProt Synonym Gene Names

PPT-C; EKA; EKA/B; EKC

UniProt Entry Name

TKN4_HUMAN

NCBI Protein Information

tachykinin-4; endokinin; preprotachykinin-C

UniProt Comments for TAC4

Function: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin-C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility. Ref.1 Ref.7 Ref.8 Ref.9

Subcellular location: Secreted

Probable.

Tissue specificity: Expressed at low levels in the uterus of both pregnant and non-pregnant women. Isoform 1 is found only in the adrenal gland and fetal liver. Isoform 2 is found in heart, liver, bone marrow, prostate, adrenal gland and testis. Isoform 3 and isoform 4 are expressed predominantly in adrenal gland and placenta. Ref.1 Ref.6

Sequence similarities: Belongs to the tachykinin family.

Sequence caution: The sequence AAI00841.1 differs from that shown. Reason: Intron retention.The sequence AAI00843.1 differs from that shown. Reason: Intron retention.The sequence AAI00844.1 differs from that shown. Reason: Intron retention.The sequence AAN77128.1 differs from that shown. Reason: Intron retention.The sequence EAW94657.1 differs from that shown. Reason: Erroneous gene model prediction.

Research Articles on TAC4

1. HKs emerge as pivotal endogenous regulators of angiogenesis through neurokinin-1 receptor

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TAC4 antibody

Reference Product	PubMed Publications
TACR1 antibody	>25 publications with TAC4 and TACR1
TAC1 antibody	>16 publications with TAC4 and TAC1
TAC3 antibody	>4 publications with TAC4 and TAC3
EKB antibody	>4 publications with TAC4 and EKB
TACR2 antibody	>4 publications with TAC4 and TACR2
TACR3 antibody	>3 publications with TAC4 and TACR3

Pathways associated with anti-TAC4 antibody

Products by Pathway	Pathway Diagram
Peptide GPCRs Pathway antibodies	Peptide GPCRs Pathway Diagram

Diseases associated with anti-TAC4 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>11 publications with TAC4 and Inflammation
Nervous System Diseases Antibodies	>9 publications with TAC4 and Nervous System Diseases
Respiratory Tract Diseases Antibodies	>2 publications with TAC4 and Respiratory Tract Diseases
Hepatitis Antibodies	>1 publications with TAC4 and Hepatitis
Pneumonia Antibodies	>1 publications with TAC4 and Pneumonia
Necrosis Antibodies	>1 publications with TAC4 and Necrosis
Liver Diseases Antibodies	>1 publications with TAC4 and Liver Diseases
Neoplasms Antibodies	>1 publications with TAC4 and Neoplasms