• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

SLC2A10 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645962

MBS645962 is an antibody targeting SLC2A10. Also known as SLC2A10 (Solute Carrier Family 2, ATS, Facilitated Glucose Transporter Member 10, Glucose Transporter Type 10, GLUT10, GLUT-10). Reactive in Human. Host: Mouse. More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SLC2A10, Monoclonal Antibody
Full Product Name
SLC2A10 (Solute Carrier Family 2, ATS, Facilitated Glucose Transporter Member 10, Glucose Transporter Type 10, GLUT10, GLUT-10)
Product Gene Name
anti-SLC2A10 antibody
Product Synonym Names
Anti -SLC2A10 (Solute Carrier Family 2, ATS, Facilitated Glucose Transporter Member 10, Glucose Transporter Type 10, GLUT10, GLUT-10)
Immunogen Sequence
SGPSCLAVPN ATGQTGLPGD SGLLQDSSLP PIPRTNEDQR EPILSTAKKT KPHPRSGD
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
1E12
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human SLC2A10.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
56,911 Da
Chromosome Location
Chromosome: 20; NC_000020.10 (45338279..45364986). Location: 20q13.1
OMIM
208050
3D Structure
ModBase 3D Structure for O95528
Immunogen
Partial recombinant corresponding to aa325-383 from human SLC2A10 (NP_110404) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-SLC2A10 antibody

Antibodies; Abs to Ion Channel
Applications Tested/Suitable for anti-SLC2A10 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-SLC2A10 antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-SLC2A10 antibody

Western Blot detection against Immunogen (32.49kD).
Mouse Anti-SLC2A10 Monoclonal Antibody – Cat# MBS645962

Western Blot (WB) of anti-SLC2A10 antibody

SLC2A10 monoclonal antibody. Western Blot analysis of SLC2A10 expression in HepG2.
Mouse Anti-SLC2A10 Monoclonal Antibody, Western Blot (WB) – Cat# MBS645962

Testing Data of anti-SLC2A10 antibody

Detection limit for recombinant GST tagged SLC2A10 is 0.03ng/ml as a capture antibody.
Mouse Anti-SLC2A10 Monoclonal Antibody, Testing Data – Cat# MBS645962

Other Notes

Small volumes of anti-SLC2A10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC2A10. It may not necessarily be applicable to this product.

NCBI GI #
13540547
NCBI GeneID
81031
NCBI Accession #
NP_110404.1
UniProt Primary Accession #
O95528
UniProt Secondary Accession #
Q3MIX5; Q9H4I6; A8K4J6
UniProt Related Accession #
O95528
GenBank Nucleotide #
NM_030777.3
NCBI Official Full Name
solute carrier family 2, facilitated glucose transporter member 10
NCBI Official Synonym Full Names
solute carrier family 2 (facilitated glucose transporter), member 10
NCBI Official Symbol
SLC2A10
NCBI Official Synonym Symbols
ATS; GLUT10
UniProt Protein Name
Solute carrier family 2, facilitated glucose transporter member 10
UniProt Synonym Protein Names
Glucose transporter type 10
Protein Family
Solute carrier family
UniProt Gene Name
SLC2A10
UniProt Synonym Gene Names
GLUT10; GLUT-10
UniProt Entry Name
GTR10_HUMAN
NCBI Protein Information
solute carrier family 2, facilitated glucose transporter member 10; GLUT-10; glucose transporter type 10

NCBI Summary for SLC2A10

This gene encodes a member of the class III facilitative glucose transporter family. The encoded protein plays a role in regulation of glucose homeostasis. Mutations in this gene have been associated with arterial tortuosity syndrome.[provided by RefSeq, Dec 2009]

UniProt Comments for SLC2A10

Function: Facilitative glucose transporter.

Subcellular location: Endomembrane system; Multi-pass membrane protein. Cytoplasm › perinuclear region Ref.9.

Tissue specificity: Widely expressed; highest levels in liver and pancreas. Ref.2

Involvement in disease: Arterial tortuosity syndrome (ATS) [MIM:208050]: An autosomal recessive disorder characterized by tortuosity and elongation of major arteries, often resulting in death at young age. Other typical features include aneurysms of large arteries and stenosis of the pulmonary artery, in association with facial features and several connective tissue manifestations such as soft skin and joint laxity. Histopathological findings include fragmentation of elastic fibers in the tunica media of large arteries.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.9 Ref.10

Sequence similarities: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. [View classification]

Biophysicochemical propertiesKinetic parameters:KM=0.28 mM for 2-deoxy-D-glucose
Show more

Research Articles on SLC2A10

1. Data show that homozygous and compound heterozygous changes found in PLOD1 and SLC2A10 may confer autosomal recessive effects, and three MYH11, ACTA2 and COL3A1 heterozygous variants were considered as putative pathogenic gene alterations.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SLC2A10 antibody

 Products by Pathway  Pathway Diagram
 Facilitative Na+-independent Glucose Transporters Pathway antibodies  Facilitative Na+-independent Glucose Transporters Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies  Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram

Diseases associated with anti-SLC2A10 antibody

 Disease Name  Pubmed Publications
 Arterial Tortuosity Syndrome Antibodies  >21 publications with SLC2A10 and Arterial Tortuosity Syndrome
 Congenital Abnormalities Antibodies  >9 publications with SLC2A10 and Congenital Abnormalities
 Nervous System Diseases Antibodies  >1 publications with SLC2A10 and Nervous System Diseases
 Hypertension Antibodies  >1 publications with SLC2A10 and Hypertension
 Breast Neoplasms Antibodies  >1 publications with SLC2A10 and Breast Neoplasms
 Brain Diseases Antibodies  >1 publications with SLC2A10 and Brain Diseases
 Hyperplasia Antibodies  >1 publications with SLC2A10 and Hyperplasia
 Fibrosis Antibodies  >1 publications with SLC2A10 and Fibrosis
 Inflammation Antibodies  >1 publications with SLC2A10 and Inflammation
 Thyroid Diseases Antibodies  >1 publications with SLC2A10 and Thyroid Diseases

Organs/Tissues associated with anti-SLC2A10 antibody

 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >16 publications with SLC2A10 and Connective Tissue
 Skin Antibodies  >6 publications with SLC2A10 and Skin
 Pancreas Antibodies  >5 publications with SLC2A10 and Pancreas
 Brain Antibodies  >4 publications with SLC2A10 and Brain
 Liver Antibodies  >4 publications with SLC2A10 and Liver
 Heart Antibodies  >3 publications with SLC2A10 and Heart
 Lung Antibodies  >3 publications with SLC2A10 and Lung
 Embryonic Tissue Antibodies  >2 publications with SLC2A10 and Embryonic Tissue
 Placenta Antibodies  >2 publications with SLC2A10 and Placenta
 Trachea Antibodies  >1 publications with SLC2A10 and Trachea
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000