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SULT1A3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645976

The human Catecholamine-Sulfating Phenol Sulfotransferase (CSPS) is the only sulfotransferase that catalyses the sulfation of catecholamins, in particular the neurotransmitter dopamine, with high activity. CSPS is required for stimulation by Mn2+ of the… More details

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Product Overview

Online Datasheet in PDF
Product Name
SULT1A3, Polyclonal Antibody
Full Product Name
SULT1A3 (Sulfotransferase 1A3/1A4, ST1A3/ST1A4, Aryl Sulfotransferase 1A3/1A4, HAST3, M-PST, Sulfotransferase, TL-PST, STM)
Product Gene Name
Product Synonym Names
Anti -SULT1A3 (Sulfotransferase 1A3/1A4, ST1A3/ST1A4, Aryl Sulfotransferase 1A3/1A4, HAST3, M-PST, Sulfotransferase, TL-PST, STM)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Purity/Purification
Purified
Purified
Specificity
Recognizes human SULT1A33. Species Crossreactivity: Mouse, Rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
34,196 Da
Chromosome Location
Chromosome: 16; NC_000016.9 (30210549..30215650). Location: 16p11.2
OMIM
600641
3D Structure
ModBase 3D Structure for P50224
Immunogen
Recombinant corresponding to human SULT1A3 expressed in E.coli.
Applications Tested/Suitable for anti-SULT1A3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SULT1A3 antibody
Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot: 1:2000
Immunohistochemistry (Paraffin): 1:400

Immunohistochemistry (IHC) of anti-SULT1A3 antibody

SULT1A3(1:400) was used in IHC to stain formalin-fixed, paraffin- embedded human lung, respiratory epithelium, followed by biotinylated goat, rabbit IgG, alkaline phosphatase-streptavidin and chromogen
Rabbit Anti-SULT1A3 Polyclonal Antibody – Cat# MBS645976

Other Notes

Small volumes of anti-SULT1A3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SULT1A3 purchase

MBS645976 is an antibody targeting SULT1A3. Also known as SULT1A3 (Sulfotransferase 1A3/1A4, ST1A3/ST1A4, Aryl Sulfotransferase 1A3/1A4, HAST3, M-PST, Sulfotransferase, TL-PST, STM). Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SULT1A3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sulfotransferase 1A3/1A4
NCBI Official Synonym Full Names
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
NCBI Official Symbol
SULT1A3
NCBI Official Synonym Symbols
STM; HAST; HAST3; M-PST; ST1A5; TL-PST; ST1A3/ST1A4
UniProt Protein Name
Sulfotransferase 1A3/1A4
UniProt Synonym Protein Names
Aryl sulfotransferase 1A3/1A4; Catecholamine-sulfating phenol sulfotransferase; HAST3; M-PST; Monoamine-sulfating phenol sulfotransferase; Placental estrogen sulfotransferase; Sulfotransferase, monoamine-preferring; Thermolabile phenol sulfotransferase
Protein Family
UniProt Gene Name
SULT1A3
UniProt Synonym Gene Names
STM; ST1A3/ST1A4; TL-PST
UniProt Entry Name
ST1A3_HUMAN
NCBI Protein Information
sulfotransferase 1A3/1A4; sulfokinase; phenol sulfotransferase 1A5; aryl sulfotransferase 1A3/1A4; dopamine-specific sulfotransferase; placental estrogen sulfotransferase; monoamine-sulfating phenosulfotransferase; catecholamine-sulfating phenol sulfotransferase; thermolabile (monoamine, M form) phenol sulfotransferase

NCBI Summary for SULT1A3

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16; this gene and SULT1A4 arose from a segmental duplication. This gene is the most centromeric of the four sulfotransferase genes. Read-through transcription exists between this gene and the upstream SLX1A (SLX1 structure-specific endonuclease subunit homolog A) gene that encodes a protein containing GIY-YIG domains. [provided by RefSeq, Nov 2010]
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UniProt Comments for SULT1A3

Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs.

Catalytic activity: 3'-phosphoadenylyl sulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate.

Subunit structure: Homodimer.

Subcellular location: Cytoplasm.

Tissue specificity: Liver, colon, kidney, lung, brain, spleen, small intestine, placenta and leukocyte.

Post-translational modification: The N-terminus is blocked.

Sequence similarities: Belongs to the sulfotransferase 1 family.

Sequence caution: Isoform 2: The sequence BAC85507.1 differs from that shown. Reason: Frameshift at position 101.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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