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CSRP2 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645996

Cysteine and glycine-rich protein 2 (CSRP2) is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the… More details

$835 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CSRP2, Polyclonal Antibody
Full Product Name
CSRP2 (Cysteine and Glycine-rich Protein 2, Cysteine-rich Protein 2, CRP2, LIM Domain Only Protein 5, LMO-5, Smooth Muscle Cell LIM Protein, SmLIM, LMO5, SMLIM)
Product Gene Name
Product Synonym Names
Anti -CSRP2 (Cysteine and Glycine-rich Protein 2, Cysteine-rich Protein 2, CRP2, LIM Domain Only Protein 5, LMO-5, Smooth Muscle Cell LIM Protein, SmLIM, LMO5, SMLIM)
Clonality
Polyclonal
Host
Goat
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human CSRP2. Species Crossreactivity
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
20,954 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (77252495..77272814, complement). Location: 12q21.1
OMIM
601871
3D Structure
ModBase 3D Structure for Q16527
Immunogen
Synthetic peptide corresponding to C-ERLGIKPESVQP, from CSRP2, at the internal region of the protein (NP_001312.1).
Applications Tested/Suitable for anti-CSRP2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-CSRP2 antibody
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: ELISA: 1:64,000
Western Blot: 0.1-0.3ug/ml, observed in human heart and in human, mouse and rat kidney lysates on ~26kD bands
Immunohistochemistry (Paraffin): 3-6ug/ml

Chemiluminescence of anti-CSRP2 antibody

(0.1ug/ml) staining of mouse kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-CSRP2 Polyclonal Antibody – Cat# MBS645996

Testing Data of anti-CSRP2 antibody

HEK293 overexpressing CRP2 and probed with(mock transfection in first lane), tested by Origene.
Goat Anti-CSRP2 Polyclonal Antibody, Testing Data – Cat# MBS645996

Other Notes

Small volumes of anti-CSRP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CSRP2 purchase

MBS645996 is an antibody targeting CSRP2. Also known as CSRP2 (Cysteine and Glycine-rich Protein 2, Cysteine-rich Protein 2, CRP2, LIM Domain Only Protein 5, LMO-5, Smooth Muscle Cell LIM Protein, SmLIM, LMO5, SMLIM). Reactive in Human, Mouse, Rat. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for CSRP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cysteine and glycine-rich protein 2
NCBI Official Synonym Full Names
cysteine and glycine-rich protein 2
NCBI Official Symbol
CSRP2
NCBI Official Synonym Symbols
CRP2; LMO5; SmLIM
UniProt Protein Name
Cysteine and glycine-rich protein 2
UniProt Synonym Protein Names
Cysteine-rich protein 2; CRP2; LIM domain only protein 5; LMO-5; Smooth muscle cell LIM protein
UniProt Gene Name
CSRP2
UniProt Synonym Gene Names
LMO5; SMLIM; CRP2; LMO-5; SmLIM
UniProt Entry Name
CSRP2_HUMAN
NCBI Protein Information
cysteine and glycine-rich protein 2; LMO-5; cysteine-rich protein 2; LIM domain only protein 5; smooth muscle cell LIM protein; LIM domain only 5, smooth muscle

NCBI Summary for CSRP2

CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3. [provided by RefSeq, Jul 2008]
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UniProt Comments for CSRP2

Function: Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system.

Subunit structure: Interacts with CSRP2BP. The LIM domain 1 is necessary and sufficient for this interaction. Interacts with GLRX3

By similarity. Ref.5

Subcellular location: Nucleus

By similarity.

Tissue specificity: Highly expressed in the aorta, but not in heart and skeletal muscle.

Sequence similarities: Contains 2 LIM zinc-binding domains.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CSRP2 antibody

Pathways associated with anti-CSRP2 antibody

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