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ZNF281 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6460552

MBS6460552 is an antibody targeting ZNF281. Also known as ZNF281 (Zinc Finger Protein 281, GC-box-Binding Zinc Finger Protein 1, Transcription Factor ZBP-99, Zinc Finger DNA-Binding Protein 99, ZNF281, GZP1, ZBP99) (APC). Reactive in Human, Mouse. Host:… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ZNF281, Polyclonal Antibody
Full Product Name
ZNF281 (Zinc Finger Protein 281, GC-box-Binding Zinc Finger Protein 1, Transcription Factor ZBP-99, Zinc Finger DNA-Binding Protein 99, ZNF281, GZP1, ZBP99) (APC)
Product Gene Name
anti-ZNF281 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes ZNF281. Species Crossreactivity: human, mouse
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
93,232 Da
3D Structure
ModBase 3D Structure for Q9Y2X9
Immunogen
KLH conjugated synthetic peptide corresponding to aa416-450 at the Central region of human ZNF281.
Conjugate
APC
Note
Preservative Free

Product Categories/Family for anti-ZNF281 antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger
Applications Tested/Suitable for anti-ZNF281 antibody
Western Blot (WB)
Application Notes for anti-ZNF281 antibody
WB: 1:1000
Applications are based on unconjugated antibody.

Product References and Citations for anti-ZNF281 antibody

Law D.J., et al. Biochem. Biophys. Res. Commun. 262:113-120(1999). Lisowsky T., et al. FEBS Lett. 453:369-374(1999). Ota T., et al. Nat. Genet. 36:40-45(2004). Gregory S.G., et al. Nature 441:315-321(2006). Zhang X., et al. Nucleic Acids Res. 31:2900-2914(2003).

Other Notes

Small volumes of anti-ZNF281 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ZNF281. It may not necessarily be applicable to this product.

NCBI GI #
6912752
NCBI GeneID
23528
NCBI Accession #
AAH51905
UniProt Primary Accession #
Q9Y2X9
UniProt Secondary Accession #
Q5RKW5; Q9NY92; A6NF48; B3KMX2
UniProt Related Accession #
Q9Y2X9
GenBank Nucleotide #
NM_012482.4
NCBI Official Full Name
zinc finger protein 281 isoform 1
NCBI Official Synonym Full Names
zinc finger protein 281
NCBI Official Symbol
ZNF281
NCBI Official Synonym Symbols
ZBP-99; ZNP-99
UniProt Protein Name
Zinc finger protein 281
UniProt Synonym Protein Names
GC-box-binding zinc finger protein 1; Transcription factor ZBP-99; Zinc finger DNA-binding protein 99
Protein Family
Zinc finger protein
UniProt Gene Name
ZNF281
UniProt Synonym Gene Names
GZP1; ZBP99
UniProt Entry Name
ZN281_HUMAN
NCBI Protein Information
zinc finger protein 281; ZNP-99 transcription factor; transcription factor ZBP-99; zinc finger DNA-binding protein 99; GC-box-binding zinc finger protein 1

UniProt Comments for ZNF281

ZNF281: Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin and ornithine decarboxylase. Binds to the G-rich box in the enhancer region of these genes. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: DNA-binding; C2H2-type zinc finger protein; Transcription factor

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; sequence-specific DNA binding; metal ion binding; transcription factor activity; transcription corepressor activity

Biological Process: embryonic body morphogenesis; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; stem cell differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent
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Research Articles on ZNF281

1. High ZNF281 expression is associated with colon and breast cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ZNF281 antibody

 Reference Product  PubMed Publications
 NANOG antibody  >2 publications with ZNF281 and NANOG
 SOX2 antibody  >1 publications with ZNF281 and SOX2

Diseases associated with anti-ZNF281 antibody

 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >1 publications with ZNF281 and Adenocarcinoma
 Skin Diseases Antibodies  >1 publications with ZNF281 and Skin Diseases
 Lung Diseases Antibodies  >1 publications with ZNF281 and Lung Diseases

Organs/Tissues associated with anti-ZNF281 antibody

 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >1 publications with ZNF281 and Prostate
 Blood Antibodies  >1 publications with ZNF281 and Blood
 Placenta Antibodies  >1 publications with ZNF281 and Placenta
 Lung Antibodies  >1 publications with ZNF281 and Lung
 Liver Antibodies  >1 publications with ZNF281 and Liver
 Kidney Antibodies  >1 publications with ZNF281 and Kidney
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