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SUOX Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646167

Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the… More details

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Product Overview

Online Datasheet in PDF
Product Name
SUOX, Polyclonal Antibody
Full Product Name
SUOX (Sulfite Oxidase, Mitochondrial)
Product Gene Name
anti-SUOX antibody
Product Synonym Names
Anti -SUOX (Sulfite Oxidase, Mitochondrial)
Immunogen Sequence
MGTLLGLGAV LAYQDHRCRA AQESTHIYTK EEVSSHTSPE TGIWVTLGSE VFDVTEFVDL HPGGPSKLML AAGGPLEPFW ALYAVHNQSH VRELLAQYKI GELNPEDKVA PTVETSDPYA DDPVRHPALK VNSQRPFNAE PPPELLTENY ITPNPIFFTR NHLPVPNLDP DTYRLHVVGA PGGQSLSLSL DDLHNFPRYE ITVTLQCAGN RRSEMTQVKE VKGLEWRTGA ISTARWAGAR LCDVLAQAGH QLCETEAHVC FEGLDSDPTG TAYGASIPLA RAMDPEAEVL LAYEMNGQPL PRDHGFPVRV VVPGVVGARH VKWLGRVSVQ PEESYSHWQR RDYKGFSPSV DWETVDFDSA PSIQELPVQS AITEPRDGET VESGEVTIKG YAWSGGGRAV IRVDVSLDGG LTWQVAKLDG EEQRPRKAWA WRLWQLKAPV PAGQKELNIV CKAVDDGYNV QPDTVAPIWN LRGVLSNAWH RVHVYVSP
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid.
Purity/Purification
Serum
Serum
Specificity
Recognizes human SUOX. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
60,283 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (56391043..56399309). Location: 12q13.2
OMIM
272300
3D Structure
ModBase 3D Structure for P51687
Immunogen
Full length human SUOX, aa1-488 (ENSP00000348440).

Product Categories/Family for anti-SUOX antibody

Antibodies; Abs to Enzymes; Oxidase
Applications Tested/Suitable for anti-SUOX antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-SUOX antibody
Suitable for use in Western Blot and Immunoprecipitation.

Western Blot (WB) of anti-SUOX antibody

SUOX rabbit polyclonal antibody. Western Blot analysis of SUOX expression in human liver.
Rabbit Anti-SUOX Polyclonal Antibody – Cat# MBS646167

Western Blot (WB) of anti-SUOX antibody

SUOX rabbit polyclonal antibody. Western Blot analysis of SUOX expression in mouse liver.
Rabbit Anti-SUOX Polyclonal Antibody, Western Blot (WB) – Cat# MBS646167

Western Blot (WB) of anti-SUOX antibody

Western Blot analysis of SUOX expression in transfected 293T cell line by SUOX polyclonal antibody. Lane 1: SUOX transfected lysate (53.9kD). Lane 2: Non-transfected lysate.
Rabbit Anti-SUOX Polyclonal Antibody, Western Blot (WB) – Cat# MBS646167

Immunoprecipitation (IP) of anti-SUOX antibody

Immunoprecipitation of SUOX transfected lysate using SUOX rabbit polyclonal antibody and Protein A Magnetic Bead and immunoblotted with SUOX purified mouse polyclonal antibody.
Rabbit Anti-SUOX Polyclonal Antibody, Immunoprecipitation (IP) – Cat# MBS646167

Other Notes

Small volumes of anti-SUOX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SUOX purchase

MBS646167 is an antibody targeting SUOX. Also known as SUOX (Sulfite Oxidase, Mitochondrial). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SUOX. It may not necessarily be applicable to this product.

NCBI GI #
74099704
NCBI GeneID
6821
NCBI Accession #
NP_001027559.1
UniProt Primary Accession #
P51687
UniProt Related Accession #
P51687
GenBank Nucleotide #
NM_001032387.1
NCBI Official Full Name
sulfite oxidase, mitochondrial
NCBI Official Synonym Full Names
sulfite oxidase
NCBI Official Symbol
SUOX
UniProt Protein Name
Sulfite oxidase, mitochondrial
Protein Family
Sulfite oxidase
UniProt Gene Name
SUOX
UniProt Entry Name
SUOX_HUMAN
NCBI Protein Information
sulfite oxidase, mitochondrial

UniProt Comments for SUOX

Catalytic activity: Sulfite + O2 + H2O = sulfate + H2O2.

Cofactor: Binds 1 heme B (iron-protoporphyrin IX) group non-covalently per subunit. Ref.4Binds 1 molybdenum-molybdopterin (Mo-MPT) cofactor per subunit

By similarity. Ref.4

Pathway: Energy metabolism; sulfur metabolism.

Subunit structure: Homodimer

By similarity.

Subcellular location: Mitochondrion intermembrane space.

Involvement in disease: Isolated sulfite oxidase deficiency (ISOD) [MIM:272300]: Characterized by neurological abnormalities including multicystic leukoencephalopathy with brain atrophy. Patients often suffer from seizures. Often leads to death at an early age.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.5 Ref.6 Ref.7 Ref.8 Ref.9

Sequence similarities: Contains 1 cytochrome b5 heme-binding domain.

Sequence caution: The sequence AAA74886.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAL08048.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
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Research Articles on SUOX

1. effect of mutation of surface residues on the heme domain on intramolecular electron transfer, and steady-state kinetics

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SUOX antibody

 Reference Product  PubMed Publications
 MOCS1 antibody  >4 publications with SUOX and MOCS1
 XDH antibody  >2 publications with SUOX and XDH
 MOCS2 antibody  >2 publications with SUOX and MOCS2

Pathways associated with anti-SUOX antibody

 Products by Pathway  Pathway Diagram
 Degradation Of Cysteine And Homocysteine Pathway antibodies  Degradation Of Cysteine And Homocysteine Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Sulfide Oxidation To Sulfate Pathway antibodies  Sulfide Oxidation To Sulfate Pathway Diagram
 Sulfur Amino Acid Metabolism Pathway antibodies  Sulfur Amino Acid Metabolism Pathway Diagram
 Sulfur Metabolism Pathway antibodies  Sulfur Metabolism Pathway Diagram
 Sulfur Metabolism Pathway antibodies  Sulfur Metabolism Pathway Diagram
 Sulfite Oxidation IV Pathway antibodies  Sulfite Oxidation IV Pathway Diagram
 Sulfite Oxidation IV Pathway antibodies  Sulfite Oxidation IV Pathway Diagram
 Superpathway Of Methionine Degradation antibodies  Superpathway Of Methionine Degradation Diagram

Diseases associated with anti-SUOX antibody

 Disease Name  Pubmed Publications
 Sulfite oxidase deficiency Antibodies  >12 publications with SUOX and Sulfite oxidase deficiency
 Brain Diseases Antibodies  >6 publications with SUOX and Brain Diseases
 Congenital Abnormalities Antibodies  >2 publications with SUOX and Congenital Abnormalities
 Neoplasms Antibodies  >2 publications with SUOX and Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with SUOX and Carcinoma, Hepatocellular
 Poisoning Antibodies  >1 publications with SUOX and Poisoning
 Liver Diseases Antibodies  >1 publications with SUOX and Liver Diseases
 Inflammation Antibodies  >1 publications with SUOX and Inflammation
 Drug-Induced Liver Injury Antibodies  >1 publications with SUOX and Drug-Induced Liver Injury
 Hypertension Antibodies  >1 publications with SUOX and Hypertension

Organs/Tissues associated with anti-SUOX antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7 publications with SUOX and Brain
 Blood Antibodies  >5 publications with SUOX and Blood
 Embryonic Tissue Antibodies  >2 publications with SUOX and Embryonic Tissue
 Placenta Antibodies  >2 publications with SUOX and Placenta
 Liver Antibodies  >1 publications with SUOX and Liver
 Ovary Antibodies  >1 publications with SUOX and Ovary
 Heart Antibodies  >1 publications with SUOX and Heart
 Ear Antibodies  >1 publications with SUOX and Ear
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