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AKAP3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6461959

MBS6461959 is an antibody targeting AKAP3. Also known as AKAP3, ID (A-kinase Anchor Protein 3, AKAP-3, Protein Kinase A-anchoring Protein 3, PRKA3, A-kinase Anchor Protein 110kD, AKAP 110, Sperm Oocyte-binding Protein, Fibrousheathin-1, Fibrousheathin I,… More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AKAP3, Polyclonal Antibody
Full Product Name
AKAP3, ID (A-kinase Anchor Protein 3, AKAP-3, Protein Kinase A-anchoring Protein 3, PRKA3, A-kinase Anchor Protein 110kD, AKAP 110, Sperm Oocyte-binding Protein, Fibrousheathin-1, Fibrousheathin I, Fibrous Sheath Protein Of 95kD, FSP95, Cancer/Testis Anti
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Purity/Purification
Purified by Immunoaffinity chromatography.
Specificity
Recognizes human AKAP3.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
94,751 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (4724676..4754343, complement). Location: 12p13.3
OMIM
604689
3D Structure
ModBase 3D Structure for O75969
Immunogen
Synthetic peptide selected from the center region of human AKAP3 (KLH).
Conjugate
MaxLight650
Note
Preservative Free

Product Categories/Family for anti-AKAP3 antibody

Applications Tested/Suitable for anti-AKAP3 antibody
Western Blot (WB), FLISA
Application Notes for anti-AKAP3 antibody
WB: 1:100-1:500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-AKAP3 antibody

1. Lefevre, A., et.al., Biochem. Biophys. Res. Commun. 259(1), 60-66 (1999).

Other Notes

Small volumes of anti-AKAP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AKAP3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
A-kinase anchor protein 3
NCBI Official Synonym Full Names
A kinase (PRKA) anchor protein 3
NCBI Official Symbol
AKAP3
NCBI Official Synonym Symbols
CT82; SOB1; FSP95; PRKA3; AKAP110; AKAP 110
UniProt Protein Name
A-kinase anchor protein 3
UniProt Synonym Protein Names
A-kinase anchor protein 110 kDa; AKAP 110; Cancer/testis antigen 82; CT82; Fibrous sheath protein of 95 kDa; FSP95; Fibrousheathin I; Fibrousheathin-1; Protein kinase A-anchoring protein 3; PRKA3; Sperm oocyte-binding protein
UniProt Gene Name
AKAP3
UniProt Synonym Gene Names
AKAP110; SOB1; AKAP-3; AKAP 110; CT82; FSP95; PRKA3
UniProt Entry Name
AKAP3_HUMAN
NCBI Protein Information
A-kinase anchor protein 3; fibrousheathin I; fibrousheathin-1; cancer/testis antigen 82; sperm oocyte-binding protein 1; A-kinase anchor protein, 110kDa; Fibrous Sheath Protein of 95 kDa; protein kinase A-anchoring protein 3; protein kinase A binding prot

NCBI Summary for AKAP3

This gene encodes a member of A-kinase anchoring proteins (AKAPs), a family of functionally related proteins that target protein kinase A to discrete locations within the cell. The encoded protein is reported to participate in protein-protein interactions with the R-subunit of the protein kinase A as well as sperm-associated proteins. This protein is expressed in spermatozoa and localized to the acrosomal region of the sperm head as well as the length of the principal piece. It may function as a regulator of motility, capacitation, and the acrosome reaction. [provided by RefSeq, May 2013]
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UniProt Comments for AKAP3

AKAP3: May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Belongs to the AKAP110 family.

Protein type: Adaptor/scaffold; Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: 12p13.3

Cellular Component: cytoplasm; acrosome; nucleus

Molecular Function: protein binding; protein kinase A binding

Biological Process: protein localization; single fertilization; acrosome reaction; transmembrane receptor protein serine/threonine kinase signaling pathway; cell motility
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-AKAP3 antibody

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