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ALOX5AP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6462512

MBS6462512 is an antibody targeting ALOX5AP. Also known as ALOX5AP, ID (Arachidonate 5-lipoxygenase-activating protein, FLAP, MK-886-binding Protein) (AP). Reactive in Human. Host: Rabbit. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ALOX5AP, Polyclonal Antibody
Full Product Name
ALOX5AP, ID (Arachidonate 5-lipoxygenase-activating protein, FLAP, MK-886-binding Protein) (AP)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase.
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Specificity
Recognizes human ALOX5AP.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
18.157
OMIM
601367
3D Structure
ModBase 3D Structure for P20292
Immunogen
Synthetic peptide selected from the center region of human ALOX5AP (KLH).
Conjugate
AP
Note
Preservative Free

Product Categories/Family for anti-ALOX5AP antibody

Applications Tested/Suitable for anti-ALOX5AP antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
Application Notes for anti-ALOX5AP antibody
IHC: 1:50-1:100
ELISA: 1:1,000
WB: 1:50-1:100
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-ALOX5AP antibody

Western blot analysis of anti-ALOX5AP Antibody (Center) in K562 cell line lysates (35ug/lane). ALOX5AP(arrow) was detected using the purified Pab.
Rabbit Anti-ALOX5AP Polyclonal Antibody – Cat# MBS6462512

Immunohistochemistry (IHC) of anti-ALOX5AP antibody

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ALOX5AP antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-ALOX5AP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6462512

Product References and Citations for anti-ALOX5AP antibody

1. Zintzaras, E., Am. J. Epidemiol. 169(5), 523-532 (2009). 2. Crosslin, D.R., Hum. Genet. 125(2), 217-229 (2009). 3. Steinhilber, D., Pharm Acta Helv 69(1), 3-14 (1994).

Other Notes

Small volumes of anti-ALOX5AP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ALOX5AP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
arachidonate 5-lipoxygenase-activating protein isoform 1
NCBI Official Synonym Full Names
arachidonate 5-lipoxygenase activating protein
NCBI Official Symbol
ALOX5AP
NCBI Official Synonym Symbols
FLAP
UniProt Protein Name
Arachidonate 5-lipoxygenase-activating protein
UniProt Synonym Protein Names
FLAP; MK-886-binding protein
UniProt Gene Name
ALOX5AP
UniProt Synonym Gene Names
FLAP
UniProt Entry Name
AL5AP_HUMAN
NCBI Protein Information
arachidonate 5-lipoxygenase-activating protein

NCBI Summary for ALOX5AP

This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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